Payment overview · 2025
General Payments
$390.78
16 reported records · 11 companies
Healthcare provider profile · identity verified
Kariappa Appachu, MD
Allopathic & Osteopathic Physicians|Internal Medicine|Nephrology · TEMPE, AZ · NPI 1942504683
Verified facts
What the public records show
CMS Open Payments records show Kariappa Appachu, MD received $390.78 in general payments during 2025 across 16 reported records.
Vantive US Healthcare LLC accounted for 26.8% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 12 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Jardiance, Lokelma, Rayaldee.
AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported FARXIGA as an associated drug or biological on 106133 records involving 42906 distinct recipient NPIs. Public Medicare Part D data also shows 32 claims for Farxiga by this doctor in 2024.
AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LOKELMA as an associated drug or biological on 6897 records involving 4326 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Lokelma by this doctor in 2024.
Boehringer Ingelheim Pharmaceuticals, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported JARDIANCE as an associated drug or biological on 123636 records involving 49438 distinct recipient NPIs. Public Medicare Part D data also shows 33 claims for Jardiance by this doctor in 2024.
OPKO Pharmaceuticals, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported RAYALDEE as an associated drug or biological on 5435 records involving 1739 distinct recipient NPIs. Public Medicare Part D data also shows 24 claims for Rayaldee by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Vantive US Healthcare LLC | Unresolved — no canonical attribution shown | $104.90 | 26.8% | 1 | 2025 |
| Travere Therapeutics, Inc. | Unresolved — no canonical attribution shown | $66.10 | 16.9% | 3 | 2025 |
| Boehringer Ingelheim Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $46.73 | 12.0% | 3 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $34.63 | 8.9% | 2 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $29.39 | 7.5% | 1 | 2025 |
| Renalytix AI, Inc. | Unresolved — no canonical attribution shown | $23.96 | 6.1% | 1 | 2025 |
| OPKO Pharmaceuticals, LLC | Unresolved — no canonical attribution shown | $20.59 | 5.3% | 1 | 2025 |
| Ardelyx, Inc. | Unresolved — no canonical attribution shown | $17.59 | 4.5% | 1 | 2025 |
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $16.52 | 4.2% | 1 | 2025 |
| GlaxoSmithKline, LLC. | Unresolved — no canonical attribution shown | $15.47 | 4.0% | 1 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $14.90 | 3.8% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $366.04 | 14 |
| Education | $24.74 | 2 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| JARDIANCE Normalized: jardiance |
Drug | Boehringer Ingelheim Pharmaceuticals, Inc. | $46.73 | 3 | 2025 |
Source payment records
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| Kerendia Normalized: kerendia |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $29.39 | 1 | 2025 |
Source payment records
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| KIDNEYINTELX BLOOD COLLECTION CONVENIENCE KIT Normalized: kidneyintelx blood collection convenience kit |
Device | Renalytix AI, Inc. | $23.96 | 1 | 2025 |
Source payment records
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| RAYALDEE Normalized: rayaldee |
Drug | OPKO Pharmaceuticals, LLC | $20.59 | 1 | 2025 |
Source payment records
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| KRYSTEXXA Normalized: krystexxa |
Biological | Amgen Inc. | $20.26 | 1 | 2025 |
Source payment records
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| IBSRELA Normalized: ibsrela |
Drug | Ardelyx, Inc. | $17.59 | 1 | 2025 |
Source payment records
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| LOKELMA Normalized: lokelma |
Drug | AstraZeneca Pharmaceuticals LP | $16.52 | 1 | 2025 |
Source payment records
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| BENLYSTA Normalized: benlysta |
Biological | GlaxoSmithKline, LLC. | $15.47 | 1 | 2025 |
Source payment records
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| Fabhalta Normalized: fabhalta |
Drug | Novartis Pharmaceuticals Corporation | $14.90 | 1 | 2025 |
Source payment records
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| Vanrafia Normalized: vanrafia |
Drug | Novartis Pharmaceuticals Corporation | $14.90 | 1 | 2025 |
Source payment records
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| TAVNEOS Normalized: tavneos |
Drug | Amgen Inc. | $14.37 | 1 | 2025 |
Source payment records
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| Filspari Normalized: filspari |
Drug | Travere Therapeutics, Inc. | $4.15 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| JARDIANCE jardiance |
2025 | Jardiance | 2024 | 33 | exact normalized | Medicare Part D |
| LOKELMA lokelma |
2025 | Lokelma | 2024 | 43 | exact normalized | Medicare Part D |
| RAYALDEE rayaldee |
2025 | Rayaldee | 2024 | 24 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| AstraZeneca Pharmaceuticals LP Exact reporting entity; no affiliate inference |
2025 | FARXIGA open payments reported associated product |
CMS Open Payments — General Payments 106133 supporting records · 42906 recipient NPIs · example record 1206131362 |
Farxiga · 2024 Exact normalized brand match · 1 Part D row |
32 | 11 |
| AstraZeneca Pharmaceuticals LP Exact reporting entity; no affiliate inference |
2025 | LOKELMA open payments reported associated product |
CMS Open Payments — General Payments 6897 supporting records · 4326 recipient NPIs · example record 1206131624 |
Lokelma · 2024 Exact normalized brand match · 1 Part D row |
43 | 15 |
| Boehringer Ingelheim Pharmaceuticals, Inc. Exact reporting entity; no affiliate inference |
2025 | JARDIANCE open payments reported associated product |
CMS Open Payments — General Payments 123636 supporting records · 49438 recipient NPIs · example record 1221811583 |
Jardiance · 2024 Exact normalized brand match · 1 Part D row |
33 | 13 |
| OPKO Pharmaceuticals, LLC Exact reporting entity; no affiliate inference |
2025 | RAYALDEE open payments reported associated product |
CMS Open Payments — General Payments 5435 supporting records · 1739 recipient NPIs · example record 1222072234 |
Rayaldee · 2024 Exact normalized brand match · 1 Part D row |
24 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Furosemide | Furosemide | 184 | 69 |
| Calcitriol | Calcitriol | 166 | 51 |
| Losartan Potassium | Losartan Potassium | 145 | 49 |
| Famotidine | Famotidine | 141 | 50 |
| Amlodipine Besylate | Amlodipine Besylate | 129 | 58 |
| Allopurinol | Allopurinol | 111 | 38 |
| Hydralazine Hcl | Hydralazine Hcl | 111 | 33 |
| Labetalol Hcl | Labetalol Hcl | 104 | 27 |
| Potassium Chloride | Potassium Chloride | 102 | 37 |
| Lisinopril | Lisinopril | 91 | 33 |
| Tamsulosin Hcl | Tamsulosin Hcl | 76 | 28 |
| Nifedipine Er | Nifedipine | 65 | 27 |
| Bumetanide | Bumetanide | 63 | 26 |
| Metolazone | Metolazone | 59 | 23 |
| Spironolactone | Spironolactone | 49 | 11 |
| Lokelma | Sodium Zirconium Cyclosilicate | 43 | 15 |
| Hydrochlorothiazide | Hydrochlorothiazide | 36 | 12 |
| Carvedilol | Carvedilol | 35 | 16 |
| Jardiance | Empagliflozin | 33 | 13 |
| Farxiga | Dapagliflozin Propanediol | 32 | 11 |
| Metoprolol Succinate | Metoprolol Succinate | 29 | suppressed |
| Sevelamer Carbonate | Sevelamer Carbonate | 26 | 13 |
| Vitamin D2 | Ergocalciferol (Vitamin D2) | 26 | 11 |
| Rayaldee | Calcifediol | 24 | suppressed |
| Finasteride | Finasteride | 21 | suppressed |
| Midodrine Hcl | Midodrine Hcl | 21 | suppressed |
| Folic Acid | Folic Acid | 15 | suppressed |
| Atorvastatin Calcium | Atorvastatin Calcium | 14 | suppressed |
| Lactulose | Lactulose | 14 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 13 | 13 |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 13 | 11 |
| Doxazosin Mesylate | Doxazosin Mesylate | 12 | suppressed |
| Ezetimibe | Ezetimibe | 12 | suppressed |
| Veltassa | Patiromer Calcium Sorbitex | 12 | suppressed |
| Clonidine Hcl | Clonidine Hcl | 11 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $390.78 · 16 records | Vantive US Healthcare LLC | BENLYSTA, Fabhalta, Filspari, IBSRELA, JARDIANCE, KIDNEYINTELX BLOOD COLLECTION CONVENIENCE KIT, KRYSTEXXA, Kerendia, LOKELMA, RAYALDEE, TAVNEOS, Vanrafia | 4 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Jardiance play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with AstraZeneca Pharmaceuticals LP?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error