Payment overview · 2025
General Payments
$4,327.77
140 reported records · 20 companies
Healthcare provider profile · identity verified
Mark Edwin Esterle, M.D.
Allopathic & Osteopathic Physicians|Internal Medicine|Pulmonary Disease · LOUISVILLE, KY · NPI 1003954876
Verified facts
What the public records show
CMS Open Payments records show Mark Edwin Esterle, M.D. received $4,327.77 in general payments during 2025 across 140 reported records.
INTUITIVE SURGICAL, INC. accounted for 33.2% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 32 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Eliquis, Ofev, Trelegy Ellipta, Uptravi.
Actelion Pharmaceuticals US, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported UPTRAVI as an associated drug or biological on 21562 records involving 9341 distinct recipient NPIs. Public Medicare Part D data also shows 12 claims for Uptravi by this doctor in 2024.
AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYMBICORT as an associated drug or biological on 71 records involving 51 distinct recipient NPIs. Public Medicare Part D data also shows 147 claims for Symbicort by this doctor in 2024.
Boehringer Ingelheim Pharmaceuticals, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported OFEV as an associated drug or biological on 14236 records involving 6873 distinct recipient NPIs. Public Medicare Part D data also shows 143 claims for Ofev by this doctor in 2024.
GlaxoSmithKline, LLC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRELEGY ELLIPTA as an associated drug or biological on 131532 records involving 37148 distinct recipient NPIs. Public Medicare Part D data also shows 698 claims for Trelegy Ellipta by this doctor in 2024.
PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 87112 records involving 36032 distinct recipient NPIs. Public Medicare Part D data also shows 26 claims for Eliquis by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| INTUITIVE SURGICAL, INC. | Unresolved — no canonical attribution shown | $1,438.37 | 33.2% | 4 | 2025 |
| GlaxoSmithKline, LLC. | Unresolved — no canonical attribution shown | $299.80 | 6.9% | 17 | 2025 |
| United Therapeutics Corporation | Unresolved — no canonical attribution shown | $278.62 | 6.4% | 5 | 2025 |
| Insmed, Inc. | Unresolved — no canonical attribution shown | $278.12 | 6.4% | 22 | 2025 |
| Actelion Pharmaceuticals US, Inc. | Unresolved — no canonical attribution shown | $270.76 | 6.3% | 8 | 2025 |
| Regeneron Healthcare Solutions, Inc. | Unresolved — no canonical attribution shown | $233.92 | 5.4% | 8 | 2025 |
| Merck Sharp & Dohme LLC | Unresolved — no canonical attribution shown | $219.74 | 5.1% | 8 | 2025 |
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $204.57 | 4.7% | 9 | 2025 |
| Grifols USA, LLC | Unresolved — no canonical attribution shown | $185.50 | 4.3% | 6 | 2025 |
| Verona Pharma, Inc. | Unresolved — no canonical attribution shown | $171.58 | 4.0% | 14 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $159.35 | 3.7% | 12 | 2025 |
| Boehringer Ingelheim Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $138.19 | 3.2% | 8 | 2025 |
| Mallinckrodt Hospital Products Inc. | Unresolved — no canonical attribution shown | $111.27 | 2.6% | 3 | 2025 |
| PFIZER INC. | Unresolved — no canonical attribution shown | $109.75 | 2.5% | 5 | 2025 |
| GENZYME CORPORATION | Unresolved — no canonical attribution shown | $86.13 | 2.0% | 4 | 2025 |
| Viatris Specialty LLC | Unresolved — no canonical attribution shown | $72.94 | 1.7% | 3 | 2025 |
| Breas Medical, Inc. | Unresolved — no canonical attribution shown | $22.44 | 0.5% | 1 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $16.37 | 0.4% | 1 | 2025 |
| CSL Behring | Unresolved — no canonical attribution shown | $15.86 | 0.4% | 1 | 2025 |
| Fisher & Paykel Healthcare Inc | Unresolved — no canonical attribution shown | $14.49 | 0.3% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $2,838.02 | 134 |
| Travel and Lodging | $1,438.37 | 4 |
| Education | $51.38 | 2 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| Da Vinci Surgical System Normalized: da vinci surgical system |
Device | INTUITIVE SURGICAL, INC. | $1,438.37 | 4 | 2025 |
Source payment records
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| UPTRAVI Normalized: uptravi |
Drug | Actelion Pharmaceuticals US, Inc. | $270.76 | 8 | 2025 |
Source payment records
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| Arikayce Normalized: arikayce |
Drug | Insmed, Inc. | $260.74 | 21 | 2025 |
Source payment records
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| DUPIXENT Normalized: dupixent |
Biological | GENZYME CORPORATION, Regeneron Healthcare Solutions, Inc. | $199.86 | 11 | 2025 |
Source payment records
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| NUCALA Normalized: nucala |
Biological | GlaxoSmithKline, LLC. | $186.07 | 10 | 2025 |
Source payment records
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| Prolastin-C Liquid Normalized: prolastin c liquid |
Biological | Grifols USA, LLC | $185.50 | 6 | 2025 |
Source payment records
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| WINREVAIR Normalized: winrevair |
Biological | Merck Sharp & Dohme LLC | $181.99 | 6 | 2025 |
Source payment records
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| Ohtuvayre Normalized: ohtuvayre |
Drug | Verona Pharma, Inc. | $171.58 | 14 | 2025 |
Source payment records
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| OPSUMIT Normalized: opsumit |
Drug | Actelion Pharmaceuticals US, Inc. | $140.92 | 2 | 2025 |
Source payment records
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| TEZSPIRE Normalized: tezspire |
Biological | Amgen Inc., AstraZeneca Pharmaceuticals LP | $128.33 | 11 | 2025 |
Source payment records
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| AIRSUPRA Normalized: airsupra |
Drug | AstraZeneca Pharmaceuticals LP | $118.82 | 4 | 2025 |
Source payment records
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| ACTHAR Normalized: acthar |
Biological | Mallinckrodt Hospital Products Inc. | $111.27 | 3 | 2025 |
Source payment records
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| BREZTRI Normalized: breztri |
Drug | AstraZeneca Pharmaceuticals LP | $100.73 | 3 | 2025 |
Source payment records
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| TRELEGY ELLIPTA Normalized: trelegy ellipta |
Drug | GlaxoSmithKline, LLC. | $98.77 | 6 | 2025 |
Source payment records
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| FASENRA Normalized: fasenra |
Biological | AstraZeneca Pharmaceuticals LP | $86.63 | 2 | 2025 |
Source payment records
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| YUPELRI Normalized: yupelri |
Drug | Viatris Specialty LLC | $72.94 | 3 | 2025 |
Source payment records
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| OFEV Normalized: ofev |
Drug | Boehringer Ingelheim Pharmaceuticals, Inc. | $62.01 | 3 | 2025 |
Source payment records
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| CUTAQUIG Normalized: cutaquig |
Biological | PFIZER INC. | $61.32 | 3 | 2025 |
Source payment records
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| JASCAYD Normalized: jascayd |
Drug | Boehringer Ingelheim Pharmaceuticals, Inc. | $49.85 | 3 | 2025 |
Source payment records
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| Tyvaso Normalized: tyvaso |
Drug | United Therapeutics Corporation | $49.65 | 3 | 2025 |
Source payment records
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| ELIQUIS Normalized: eliquis |
Drug | PFIZER INC. | $48.43 | 2 | 2025 |
Source payment records
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| NURTEC ODT Normalized: nurtec odt |
Drug | PFIZER INC. | $48.43 | 2 | 2025 |
Source payment records
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| PAXLOVID Normalized: paxlovid |
Drug | PFIZER INC. | $48.43 | 2 | 2025 |
Source payment records
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| TAVNEOS Normalized: tavneos |
Drug | Amgen Inc. | $41.31 | 2 | 2025 |
Source payment records
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| ZERBAXA Normalized: zerbaxa |
Drug | Merck Sharp & Dohme LLC | $37.75 | 2 | 2025 |
Source payment records
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| Brinsupri Normalized: brinsupri |
Drug | Insmed, Inc. | $37.72 | 4 | 2025 |
Source payment records
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| PANZYGA Normalized: panzyga |
Biological | PFIZER INC. | $35.92 | 2 | 2025 |
Source payment records
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| Vivo 45 LS Normalized: vivo 45 ls |
Device | Breas Medical, Inc. | $22.44 | 1 | 2025 |
Source payment records
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| Adempas Normalized: adempas |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $16.37 | 1 | 2025 |
Source payment records
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| Kcentra Normalized: kcentra |
Biological | CSL Behring | $15.86 | 1 | 2025 |
Source payment records
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| AREXVY Normalized: arexvy |
Biological | GlaxoSmithKline, LLC. | $14.96 | 1 | 2025 |
Source payment records
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| FISHER & PAYKEL HEALTHCARE Normalized: fisher paykel healthcare |
Device | Fisher & Paykel Healthcare Inc | $14.49 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| ELIQUIS eliquis |
2025 | Eliquis | 2024 | 26 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| OFEV ofev |
2025 | Ofev | 2024 | 143 | exact normalized | Medicare Part D |
| TRELEGY ELLIPTA trelegy ellipta |
2025 | Trelegy Ellipta | 2024 | 698 | exact normalized | Medicare Part D |
| UPTRAVI uptravi |
2025 | Uptravi | 2024 | 12 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Actelion Pharmaceuticals US, Inc. Exact reporting entity; no affiliate inference |
2025 | UPTRAVI open payments reported associated product |
CMS Open Payments — General Payments 21562 supporting records · 9341 recipient NPIs · example record 1174163984 |
Uptravi · 2024 Exact normalized brand match · 1 Part D row |
12 | suppressed by CMS |
| AstraZeneca Pharmaceuticals LP Exact reporting entity; no affiliate inference |
2025 | SYMBICORT open payments reported associated product |
CMS Open Payments — General Payments 71 supporting records · 51 recipient NPIs · example record 1206132610 |
Symbicort · 2024 Exact normalized brand match · 1 Part D row |
147 | 37 |
| Boehringer Ingelheim Pharmaceuticals, Inc. Exact reporting entity; no affiliate inference |
2025 | OFEV open payments reported associated product |
CMS Open Payments — General Payments 14236 supporting records · 6873 recipient NPIs · example record 1221811762 |
Ofev · 2024 Exact normalized brand match · 1 Part D row |
143 | 20 |
| GlaxoSmithKline, LLC. Exact reporting entity; no affiliate inference |
2025 | TRELEGY ELLIPTA open payments reported associated product |
CMS Open Payments — General Payments 131532 supporting records · 37148 recipient NPIs · example record 1190332369 |
Trelegy Ellipta · 2024 Exact normalized brand match · 1 Part D row |
698 | 141 |
| PFIZER INC. Exact reporting entity; no affiliate inference |
2025 | ELIQUIS open payments reported associated product |
CMS Open Payments — General Payments 87112 supporting records · 36032 recipient NPIs · example record 1228794063 |
Eliquis · 2024 Exact normalized brand match · 1 Part D row |
26 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 698 | 141 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 397 | 198 |
| Breo Ellipta | Fluticasone/Vilanterol | 230 | 58 |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 166 | 43 |
| Symbicort | Budesonide/Formoterol Fumarate | 147 | 37 |
| Prednisone | Prednisone | 145 | 63 |
| Ofev | Nintedanib Esylate | 143 | 20 |
| Breztri Aerosphere | Budesonide/Glycopyr/Formoterol | 123 | 30 |
| Anoro Ellipta | Umeclidinium Brm/Vilanterol Tr | 120 | 21 |
| Montelukast Sodium | Montelukast Sodium | 116 | 30 |
| Ventolin Hfa | Albuterol Sulfate | 116 | 58 |
| Theophylline Er | Theophylline Anhydrous | 100 | 18 |
| Azithromycin | Azithromycin | 94 | 25 |
| Budesonide-Formoterol Fumarate | Budesonide/Formoterol Fumarate | 94 | 32 |
| Spiriva Respimat | Tiotropium Bromide | 91 | 26 |
| Stiolto Respimat | Tiotropium Br/Olodaterol Hcl | 83 | 12 |
| Doxycycline Hyclate | Doxycycline Hyclate | 56 | 52 |
| Arnuity Ellipta | Fluticasone Furoate | 49 | suppressed |
| Wixela Inhub | Fluticasone Propion/Salmeterol | 47 | 15 |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 27 | 25 |
| Eliquis | Apixaban | 26 | suppressed |
| Mycophenolate Mofetil | Mycophenolate Mofetil | 26 | suppressed |
| Advair Hfa | Fluticasone Propion/Salmeterol | 25 | suppressed |
| Pirfenidone | Pirfenidone | 25 | suppressed |
| Furosemide | Furosemide | 23 | suppressed |
| Methotrexate | Methotrexate Sodium | 22 | suppressed |
| Clonazepam | Clonazepam | 19 | suppressed |
| Levofloxacin | Levofloxacin | 18 | 18 |
| Spiriva Handihaler | Tiotropium Bromide | 16 | suppressed |
| Advair Diskus | Fluticasone Propion/Salmeterol | 14 | suppressed |
| Pantoprazole Sodium | Pantoprazole Sodium | 14 | suppressed |
| Azathioprine | Azathioprine | 13 | suppressed |
| Combivent Respimat | Ipratropium/Albuterol Sulfate | 13 | suppressed |
| Tyvaso Dpi | Treprostinil | 13 | suppressed |
| Ambrisentan | Ambrisentan | 12 | suppressed |
| Ipratropium Bromide | Ipratropium Bromide | 12 | suppressed |
| Singulair | Montelukast Sodium | 12 | suppressed |
| Tadalafil | Tadalafil | 12 | suppressed |
| Uptravi | Selexipag | 12 | suppressed |
| Modafinil | Modafinil | 11 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $4,327.77 · 140 records | INTUITIVE SURGICAL, INC. | ACTHAR, AIRSUPRA, AREXVY, Adempas, Arikayce, BREZTRI, Brinsupri, CUTAQUIG, DUPIXENT, Da Vinci Surgical System, ELIQUIS, FASENRA, FISHER & PAYKEL HEALTHCARE, JASCAYD, Kcentra, NUCALA, NURTEC ODT, OFEV, OPSUMIT, Ohtuvayre, PANZYGA, PAXLOVID, Prolastin-C Liquid, TAVNEOS, TEZSPIRE, TRELEGY ELLIPTA, Tyvaso, UPTRAVI, Vivo 45 LS, WINREVAIR, YUPELRI, ZERBAXA | 5 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Eliquis play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Actelion Pharmaceuticals US, Inc.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error