Payment overview · 2025
General Payments
$14.38
1 reported records · 1 companies
Healthcare provider profile · identity verified
Adele R Sykes, MD
Allopathic & Osteopathic Physicians|Internal Medicine · DENVER, CO · NPI 1033272562
Verified facts
What the public records show
CMS Open Payments records show Adele R Sykes, MD received $14.38 in general payments during 2025 across 1 reported records.
VERTEX PHARMACEUTICALS INCORPORATED accounted for 100.0% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 1 associated product.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| VERTEX PHARMACEUTICALS INCORPORATED | Unresolved — no canonical attribution shown | $14.38 | 100.0% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $14.38 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| ALYFTREK Normalized: alyftrek |
Drug | VERTEX PHARMACEUTICALS INCORPORATED | $14.38 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
No exact normalized or approved-alias overlap was found in the loaded Part D year. This does not mean the doctor never prescribed the product.
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
No publishable same-company prescribing overlap was found in the loaded Part D year. This does not mean the doctor never prescribed a drug reported elsewhere by a paying company.
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Levothyroxine Sodium | Levothyroxine Sodium | 490 | 134 |
| Atorvastatin Calcium | Atorvastatin Calcium | 343 | 99 |
| Amlodipine Besylate | Amlodipine Besylate | 249 | 67 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 197 | 55 |
| Lisinopril | Lisinopril | 157 | 50 |
| Losartan Potassium | Losartan Potassium | 154 | 39 |
| Omeprazole | Omeprazole | 146 | 43 |
| Gabapentin | Gabapentin | 135 | 35 |
| Escitalopram Oxalate | Escitalopram Oxalate | 132 | 42 |
| Bupropion Xl | Bupropion Hcl | 113 | 39 |
| Pravastatin Sodium | Pravastatin Sodium | 110 | 36 |
| Trazodone Hcl | Trazodone Hcl | 105 | 37 |
| Metformin Hcl | Metformin Hcl | 92 | 28 |
| Citalopram Hbr | Citalopram Hydrobromide | 84 | 19 |
| Tramadol Hcl | Tramadol Hcl | 80 | 17 |
| Triamterene-Hydrochlorothiazid | Triamterene/Hydrochlorothiazid | 79 | 27 |
| Duloxetine Hcl | Duloxetine Hcl | 75 | 20 |
| Alprazolam | Alprazolam | 74 | 21 |
| Hydrochlorothiazide | Hydrochlorothiazide | 74 | 26 |
| Metformin Hcl Er | Metformin Hcl | 74 | 23 |
| Alendronate Sodium | Alendronate Sodium | 73 | 22 |
| Potassium Chloride | Potassium Chloride | 72 | 26 |
| Pantoprazole Sodium | Pantoprazole Sodium | 71 | 27 |
| Zolpidem Tartrate | Zolpidem Tartrate | 71 | 26 |
| Synthroid | Levothyroxine Sodium | 70 | 20 |
| Mirtazapine | Mirtazapine | 68 | 20 |
| Simvastatin | Simvastatin | 65 | 20 |
| Estradiol | Estradiol | 64 | 26 |
| Metoprolol Tartrate | Metoprolol Tartrate | 64 | 18 |
| Meloxicam | Meloxicam | 61 | 28 |
| Metoprolol Succinate | Metoprolol Succinate | 60 | 17 |
| Venlafaxine Hcl Er | Venlafaxine Hcl | 60 | 12 |
| Ozempic | Semaglutide | 59 | 11 |
| Tizanidine Hcl | Tizanidine Hcl | 56 | 18 |
| Allopurinol | Allopurinol | 55 | 17 |
| Lorazepam | Lorazepam | 52 | 16 |
| Montelukast Sodium | Montelukast Sodium | 52 | 14 |
| Eliquis | Apixaban | 51 | 12 |
| Clonazepam | Clonazepam | 49 | suppressed |
| Lisinopril-Hydrochlorothiazide | Lisinopril/Hydrochlorothiazide | 48 | 15 |
| Donepezil Hcl | Donepezil Hcl | 46 | suppressed |
| Sertraline Hcl | Sertraline Hcl | 46 | 16 |
| Celecoxib | Celecoxib | 43 | 13 |
| Sumatriptan Succinate | Sumatriptan Succinate | 43 | suppressed |
| Furosemide | Furosemide | 40 | 16 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 37 | 14 |
| Oxycodone Hcl | Oxycodone Hcl | 37 | suppressed |
| Carvedilol | Carvedilol | 35 | suppressed |
| Oxycodone-Acetaminophen | Oxycodone Hcl/Acetaminophen | 35 | suppressed |
| Diazepam | Diazepam | 34 | suppressed |
| Fluoxetine Hcl | Fluoxetine Hcl | 32 | suppressed |
| Tamsulosin Hcl | Tamsulosin Hcl | 31 | suppressed |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 30 | suppressed |
| Buspirone Hcl | Buspirone Hcl | 29 | suppressed |
| Vitamin D2 | Ergocalciferol (Vitamin D2) | 29 | 11 |
| Propranolol Hcl Er | Propranolol Hcl | 28 | suppressed |
| Valacyclovir | Valacyclovir Hcl | 28 | 15 |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 27 | suppressed |
| Quetiapine Fumarate | Quetiapine Fumarate | 27 | suppressed |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 25 | 16 |
| Famotidine | Famotidine | 23 | suppressed |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 23 | suppressed |
| Spironolactone | Spironolactone | 23 | suppressed |
| Acyclovir | Acyclovir | 22 | 11 |
| Dotti | Estradiol | 22 | suppressed |
| Losartan-Hydrochlorothiazide | Losartan/Hydrochlorothiazide | 22 | suppressed |
| Diclofenac Sodium | Diclofenac Sodium | 21 | suppressed |
| Desvenlafaxine Succinate Er | Desvenlafaxine Succinate | 20 | suppressed |
| Jardiance | Empagliflozin | 20 | suppressed |
| Mounjaro | Tirzepatide | 20 | suppressed |
| Topiramate | Topiramate | 20 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 19 | suppressed |
| Liothyronine Sodium | Liothyronine Sodium | 19 | suppressed |
| Pregabalin | Pregabalin | 19 | suppressed |
| Temazepam | Temazepam | 19 | suppressed |
| Valsartan-Hydrochlorothiazide | Valsartan/Hydrochlorothiazide | 19 | suppressed |
| Hydrocortisone | Hydrocortisone | 18 | suppressed |
| Olmesartan-Hydrochlorothiazide | Olmesartan/Hydrochlorothiazide | 18 | suppressed |
| Rybelsus | Semaglutide | 18 | suppressed |
| Oxybutynin Chloride | Oxybutynin Chloride | 17 | suppressed |
| Warfarin Sodium | Warfarin Sodium | 17 | suppressed |
| Cyclobenzaprine Hcl | Cyclobenzaprine Hcl | 16 | suppressed |
| Fluticasone Propionate | Fluticasone Propionate | 16 | suppressed |
| Hydroxyzine Pamoate | Hydroxyzine Pamoate | 16 | suppressed |
| Morphine Sulfate Er | Morphine Sulfate | 16 | suppressed |
| Premarin | Estrogens, Conjugated | 16 | suppressed |
| Valsartan | Valsartan | 16 | suppressed |
| Clopidogrel | Clopidogrel Bisulfate | 15 | suppressed |
| Ipratropium Bromide | Ipratropium Bromide | 15 | suppressed |
| Memantine Hcl | Memantine Hcl | 15 | suppressed |
| Progesterone | Progesterone, Micronized | 15 | suppressed |
| Cephalexin | Cephalexin | 14 | 13 |
| Dicyclomine Hcl | Dicyclomine Hcl | 14 | suppressed |
| Ezetimibe | Ezetimibe | 14 | suppressed |
| Butalbital-Aspirin-Caffeine | Butalbital/Aspirin/Caffeine | 13 | suppressed |
| Esomeprazole Magnesium | Esomeprazole Magnesium | 13 | suppressed |
| Irbesartan | Irbesartan | 13 | suppressed |
| Naratriptan Hcl | Naratriptan Hcl | 13 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 13 | suppressed |
| Lovastatin | Lovastatin | 12 | suppressed |
| Prednisone | Prednisone | 12 | suppressed |
| Spiriva Respimat | Tiotropium Bromide | 12 | suppressed |
| Sucralfate | Sucralfate | 12 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 11 | suppressed |
| Climara Pro | Estradiol/Levonorgestrel | 11 | suppressed |
| Estradiol (Twice Weekly) | Estradiol | 11 | suppressed |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 11 | suppressed |
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 11 | suppressed |
| Zolpidem Tartrate Er | Zolpidem Tartrate | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $14.38 · 1 records | VERTEX PHARMACEUTICALS INCORPORATED | ALYFTREK | — | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
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