Payment overview · 2025
General Payments
$723.96
28 reported records · 12 companies
Healthcare provider profile · identity verified
Constantine John Tsamasfyros, M.D.
Allopathic & Osteopathic Physicians|Internal Medicine · DENVER, CO · NPI 1114989332
Verified facts
What the public records show
CMS Open Payments records show Constantine John Tsamasfyros, M.D. received $723.96 in general payments during 2025 across 28 reported records.
AstraZeneca Pharmaceuticals LP accounted for 33.7% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 16 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Trelegy Ellipta.
AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYMBICORT as an associated drug or biological on 71 records involving 51 distinct recipient NPIs. Public Medicare Part D data also shows 15 claims for Symbicort by this doctor in 2024.
GlaxoSmithKline, LLC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRELEGY ELLIPTA as an associated drug or biological on 131532 records involving 37148 distinct recipient NPIs. Public Medicare Part D data also shows 30 claims for Trelegy Ellipta by this doctor in 2024.
Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 19 claims for Ozempic by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $244.01 | 33.7% | 7 | 2025 |
| GlaxoSmithKline, LLC. | Unresolved — no canonical attribution shown | $95.63 | 13.2% | 4 | 2025 |
| Neurocrine BioSciences, Inc. | Unresolved — no canonical attribution shown | $83.94 | 11.6% | 3 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $78.62 | 10.9% | 4 | 2025 |
| Teva Pharmaceuticals USA, Inc. | Unresolved — no canonical attribution shown | $56.33 | 7.8% | 2 | 2025 |
| ABBVIE INC. | Unresolved — no canonical attribution shown | $30.34 | 4.2% | 2 | 2025 |
| Electromed, Inc. | Unresolved — no canonical attribution shown | $28.97 | 4.0% | 1 | 2025 |
| Exact Sciences Corporation | Unresolved — no canonical attribution shown | $27.84 | 3.9% | 1 | 2025 |
| ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) | Unresolved — no canonical attribution shown | $26.00 | 3.6% | 1 | 2025 |
| ANI Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $18.49 | 2.5% | 1 | 2025 |
| Novo Nordisk Inc | Unresolved — no canonical attribution shown | $17.48 | 2.4% | 1 | 2025 |
| Paratek Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $16.31 | 2.2% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $723.96 | 28 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| AIRSUPRA Normalized: airsupra |
Drug | AstraZeneca Pharmaceuticals LP | $150.44 | 2 | 2025 |
Source payment records
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| TRELEGY ELLIPTA Normalized: trelegy ellipta |
Drug | GlaxoSmithKline, LLC. | $95.63 | 4 | 2025 |
Source payment records
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| INGREZZA Normalized: ingrezza |
Drug | Neurocrine BioSciences, Inc. | $83.94 | 3 | 2025 |
Source payment records
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| OTEZLA Normalized: otezla |
Drug | Amgen Inc. | $59.55 | 3 | 2025 |
Source payment records
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| REPATHA Normalized: repatha |
Biological | Amgen Inc. | $59.55 | 3 | 2025 |
Source payment records
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| AUSTEDO XR Normalized: austedo xr |
Drug | Teva Pharmaceuticals USA, Inc. | $56.33 | 2 | 2025 |
Source payment records
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| BREZTRI Normalized: breztri |
Drug | AstraZeneca Pharmaceuticals LP | $55.84 | 3 | 2025 |
Source payment records
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| VRAYLAR Normalized: vraylar |
Drug | ABBVIE INC. | $30.34 | 2 | 2025 |
Source payment records
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| SMARTVEST Normalized: smartvest |
Device | Electromed, Inc. | $28.97 | 1 | 2025 |
Source payment records
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| Cologuard Collection Kit Normalized: cologuard collection kit |
Device | Exact Sciences Corporation | $27.84 | 1 | 2025 |
Source payment records
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| CAPLYTA Normalized: caplyta |
Drug | ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) | $26.00 | 1 | 2025 |
Source payment records
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| EVENITY Normalized: evenity |
Biological | Amgen Inc. | $19.07 | 1 | 2025 |
Source payment records
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| PROLIA Normalized: prolia |
Biological | Amgen Inc. | $19.07 | 1 | 2025 |
Source payment records
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| PURIFIED CORTROPHIN GEL Normalized: purified cortrophin gel |
Drug | ANI Pharmaceuticals, Inc. | $18.49 | 1 | 2025 |
Source payment records
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| Wegovy Normalized: wegovy |
Drug | Novo Nordisk Inc | $17.48 | 1 | 2025 |
Source payment records
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| NUZYRA Normalized: nuzyra |
Drug | Paratek Pharmaceuticals, Inc. | $16.31 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| TRELEGY ELLIPTA trelegy ellipta |
2025 | Trelegy Ellipta | 2024 | 30 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| AstraZeneca Pharmaceuticals LP Exact reporting entity; no affiliate inference |
2025 | SYMBICORT open payments reported associated product |
CMS Open Payments — General Payments 71 supporting records · 51 recipient NPIs · example record 1206132610 |
Symbicort · 2024 Exact normalized brand match · 1 Part D row |
15 | suppressed by CMS |
| GlaxoSmithKline, LLC. Exact reporting entity; no affiliate inference |
2025 | TRELEGY ELLIPTA open payments reported associated product |
CMS Open Payments — General Payments 131532 supporting records · 37148 recipient NPIs · example record 1190332369 |
Trelegy Ellipta · 2024 Exact normalized brand match · 1 Part D row |
30 | suppressed by CMS |
| Novo Nordisk Inc Exact reporting entity; no affiliate inference |
2025 | Ozempic open payments reported associated product |
CMS Open Payments — General Payments 261625 supporting records · 77793 recipient NPIs · example record 1188130076 |
Ozempic · 2024 Exact normalized brand match · 1 Part D row |
19 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Atorvastatin Calcium | Atorvastatin Calcium | 283 | 93 |
| Amlodipine Besylate | Amlodipine Besylate | 187 | 59 |
| Potassium Chloride | Potassium Chloride | 171 | 62 |
| Famotidine | Famotidine | 163 | 65 |
| Oxycodone Hcl | Oxycodone Hcl | 163 | 25 |
| Lisinopril | Lisinopril | 140 | 45 |
| Losartan Potassium | Losartan Potassium | 134 | 40 |
| Metformin Hcl | Metformin Hcl | 111 | 36 |
| Zolpidem Tartrate | Zolpidem Tartrate | 104 | 18 |
| Levothyroxine Sodium | Levothyroxine Sodium | 86 | 28 |
| Oxycodone-Acetaminophen | Oxycodone Hcl/Acetaminophen | 86 | suppressed |
| Tamsulosin Hcl | Tamsulosin Hcl | 84 | 32 |
| Dextroamphetamine-Amphetamine | Dextroamphetamine/Amphetamine | 78 | 12 |
| Finasteride | Finasteride | 78 | 31 |
| Prednisone | Prednisone | 76 | 25 |
| Azithromycin | Azithromycin | 71 | 47 |
| Allopurinol | Allopurinol | 70 | 23 |
| Metoprolol Succinate | Metoprolol Succinate | 70 | 22 |
| Gabapentin | Gabapentin | 69 | 22 |
| Furosemide | Furosemide | 59 | 22 |
| Nebivolol Hcl | Nebivolol Hcl | 58 | 26 |
| Sertraline Hcl | Sertraline Hcl | 58 | 16 |
| Diazepam | Diazepam | 57 | 11 |
| Carvedilol | Carvedilol | 46 | 15 |
| Metoprolol Tartrate | Metoprolol Tartrate | 43 | suppressed |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 43 | 13 |
| Omeprazole | Omeprazole | 42 | 18 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 41 | 17 |
| Olmesartan-Hydrochlorothiazide | Olmesartan/Hydrochlorothiazide | 40 | 13 |
| Alprazolam | Alprazolam | 38 | suppressed |
| Hydrochlorothiazide | Hydrochlorothiazide | 38 | 15 |
| Breztri Aerosphere | Budesonide/Glycopyr/Formoterol | 37 | 16 |
| Mirtazapine | Mirtazapine | 36 | 13 |
| Pregabalin | Pregabalin | 36 | 12 |
| Clopidogrel | Clopidogrel Bisulfate | 34 | suppressed |
| Eliquis | Apixaban | 34 | suppressed |
| Temazepam | Temazepam | 32 | suppressed |
| Lisinopril-Hydrochlorothiazide | Lisinopril/Hydrochlorothiazide | 31 | 13 |
| Clotrimazole-Betamethasone | Clotrimazole/Betamethasone Dip | 30 | 17 |
| Escitalopram Oxalate | Escitalopram Oxalate | 30 | 12 |
| Liothyronine Sodium | Liothyronine Sodium | 30 | suppressed |
| Metformin Hcl Er | Metformin Hcl | 30 | 11 |
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 30 | suppressed |
| Lorazepam | Lorazepam | 29 | suppressed |
| Dexamethasone | Dexamethasone | 28 | 23 |
| Methotrexate | Methotrexate Sodium | 28 | suppressed |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 28 | suppressed |
| Pantoprazole Sodium | Pantoprazole Sodium | 28 | 12 |
| Valsartan | Valsartan | 26 | suppressed |
| Donepezil Hcl | Donepezil Hcl | 24 | suppressed |
| Ezetimibe | Ezetimibe | 24 | 12 |
| Warfarin Sodium | Warfarin Sodium | 24 | suppressed |
| Xarelto | Rivaroxaban | 24 | suppressed |
| Trazodone Hcl | Trazodone Hcl | 23 | suppressed |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 21 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 21 | suppressed |
| Jardiance | Empagliflozin | 20 | suppressed |
| Ozempic | Semaglutide | 19 | suppressed |
| Bupropion Xl | Bupropion Hcl | 18 | suppressed |
| Clonazepam | Clonazepam | 18 | suppressed |
| Alendronate Sodium | Alendronate Sodium | 17 | suppressed |
| Lamotrigine | Lamotrigine | 17 | suppressed |
| Losartan-Hydrochlorothiazide | Losartan/Hydrochlorothiazide | 17 | suppressed |
| Acyclovir | Acyclovir | 16 | suppressed |
| Carbidopa-Levodopa | Carbidopa/Levodopa | 16 | suppressed |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 15 | 12 |
| Duloxetine Hcl | Duloxetine Hcl | 15 | suppressed |
| Simvastatin | Simvastatin | 15 | suppressed |
| Symbicort | Budesonide/Formoterol Fumarate | 15 | suppressed |
| Amitriptyline Hcl | Amitriptyline Hcl | 14 | suppressed |
| Amlodipine Besylate-Benazepril | Amlodipine Besylate/Benazepril | 14 | suppressed |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 14 | suppressed |
| Oxybutynin Chloride | Oxybutynin Chloride | 14 | suppressed |
| Trulicity | Dulaglutide | 14 | suppressed |
| Baclofen | Baclofen | 13 | suppressed |
| Diclofenac Potassium | Diclofenac Potassium | 13 | suppressed |
| Meloxicam | Meloxicam | 13 | suppressed |
| Nano 2nd Gen Pen Needle | Pen Needle, Diabetic | 13 | suppressed |
| Acetaminophen-Codeine | Acetaminophen With Codeine | 12 | suppressed |
| Budesonide-Formoterol Fumarate | Budesonide/Formoterol Fumarate | 12 | suppressed |
| Diclofenac Sodium | Diclofenac Sodium | 12 | suppressed |
| Doxycycline Monohydrate | Doxycycline Monohydrate | 12 | suppressed |
| Insulin Lispro Kwikpen U-100 | Insulin Lispro | 11 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $723.96 · 28 records | AstraZeneca Pharmaceuticals LP | AIRSUPRA, AUSTEDO XR, BREZTRI, CAPLYTA, Cologuard Collection Kit, EVENITY, INGREZZA, NUZYRA, OTEZLA, PROLIA, PURIFIED CORTROPHIN GEL, REPATHA, SMARTVEST, TRELEGY ELLIPTA, VRAYLAR, Wegovy | 3 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Trelegy Ellipta play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with AstraZeneca Pharmaceuticals LP?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error