Healthcare provider profile · identity verified

Karl M Holmes, PAC

Physician Assistants & Advanced Practice Nursing Providers|Physician Assistant · KEYSTONE, IA · NPI 1124006887

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Karl M Holmes, PAC received $83.86 in general payments during 2025 across 3 reported records.

Lilly USA, LLC accounted for 53.7% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 1 associated product.

A separate comparison found the same explicitly named product in public Medicare Part D data: Ozempic.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported JARDIANCE as an associated drug or biological on 47708 records involving 23833 distinct recipient NPIs. Public Medicare Part D data also shows 22 claims for Jardiance by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRULICITY as an associated drug or biological on 71 records involving 57 distinct recipient NPIs. Public Medicare Part D data also shows 17 claims for Trulicity by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 77 claims for Ozempic by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$83.86

3 reported records · 2 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
Lilly USA, LLC Unresolved — no canonical attribution shown $45.0053.7%12025
Novo Nordisk Inc Unresolved — no canonical attribution shown $38.8646.3%22025

What were the payments for?

Payment categories

CategoryAmountRecords
Education$45.001
Food and Beverage$38.862

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
Ozempic
Normalized: ozempic
Drug Novo Nordisk Inc $38.86 2 2025
Source payment records

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
Ozempic
ozempic
2025 Ozempic 2024 77 exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 JARDIANCE
open payments reported associated product
CMS Open Payments — General Payments
47708 supporting records · 23833 recipient NPIs · example record 1186464557
Jardiance · 2024
Exact normalized brand match · 1 Part D row
22 suppressed by CMS
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 TRULICITY
open payments reported associated product
CMS Open Payments — General Payments
71 supporting records · 57 recipient NPIs · example record 1186464601
Trulicity · 2024
Exact normalized brand match · 1 Part D row
17 suppressed by CMS
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Ozempic
open payments reported associated product
CMS Open Payments — General Payments
261625 supporting records · 77793 recipient NPIs · example record 1188130076
Ozempic · 2024
Exact normalized brand match · 1 Part D row
77 13

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Levothyroxine SodiumLevothyroxine Sodium28873
Amlodipine BesylateAmlodipine Besylate23872
Atorvastatin CalciumAtorvastatin Calcium23871
LisinoprilLisinopril23566
Rosuvastatin CalciumRosuvastatin Calcium22766
Pantoprazole SodiumPantoprazole Sodium18250
Metoprolol SuccinateMetoprolol Succinate17951
HydrochlorothiazideHydrochlorothiazide14538
OmeprazoleOmeprazole14545
Potassium ChloridePotassium Chloride14336
FurosemideFurosemide13947
PrednisonePrednisone12973
Tramadol HclTramadol Hcl12731
MeloxicamMeloxicam12436
Losartan PotassiumLosartan Potassium12332
Hydrocodone-AcetaminophenHydrocodone/Acetaminophen12012
Metformin Hcl ErMetformin Hcl11735
SimvastatinSimvastatin10224
EzetimibeEzetimibe9722
Albuterol Sulfate HfaAlbuterol Sulfate9651
Bupropion XlBupropion Hcl9419
Ibandronate SodiumIbandronate Sodium9329
GabapentinGabapentin9227
Metformin HclMetformin Hcl9026
AtenololAtenolol8622
Trazodone HclTrazodone Hcl7917
OzempicSemaglutide7713
Zolpidem TartrateZolpidem Tartrate7214
Tresiba Flextouch U-200Insulin Degludec6712
AzithromycinAzithromycin6659
Duloxetine HclDuloxetine Hcl6515
LorazepamLorazepam6412
Sertraline HclSertraline Hcl6419
MethylprednisoloneMethylprednisolone6357
Fluticasone PropionateFluticasone Propionate6027
Cyclobenzaprine HclCyclobenzaprine Hcl5820
FarxigaDapagliflozin Propanediol5716
XareltoRivaroxaban55suppressed
EliquisApixaban5413
Ropinirole HclRopinirole Hcl5417
Venlafaxine Hcl ErVenlafaxine Hcl53suppressed
Montelukast SodiumMontelukast Sodium5216
LovastatinLovastatin5116
Pravastatin SodiumPravastatin Sodium5118
AllopurinolAllopurinol5018
CefadroxilCefadroxil4935
AlprazolamAlprazolam48suppressed
FamotidineFamotidine4814
Escitalopram OxalateEscitalopram Oxalate4612
Metoprolol TartrateMetoprolol Tartrate4616
Buspirone HclBuspirone Hcl4513
ClonazepamClonazepam45suppressed
Tamsulosin HclTamsulosin Hcl4515
Amoxicillin-Clavulanate PotassAmoxicillin/Potassium Clav4341
Paroxetine HclParoxetine Hcl43suppressed
RamiprilRamipril42suppressed
Nitrofurantoin Mono-MacroNitrofurantoin Monohyd/M-Cryst4132
PregabalinPregabalin4113
Repatha SureclickEvolocumab39suppressed
LoperamideLoperamide Hcl36suppressed
SynthroidLevothyroxine Sodium36suppressed
AmoxicillinAmoxicillin3426
Doxycycline MonohydrateDoxycycline Monohydrate3429
Sumatriptan SuccinateSumatriptan Succinate34suppressed
CefdinirCefdinir3125
ClopidogrelClopidogrel Bisulfate31suppressed
Alendronate SodiumAlendronate Sodium30suppressed
Verapamil ErVerapamil Hcl30suppressed
FenofibrateFenofibrate29suppressed
FenofibrateFenofibrate Nanocrystallized28suppressed
MirtazapineMirtazapine28suppressed
Tresiba Flextouch U-100Insulin Degludec28suppressed
CarvedilolCarvedilol27suppressed
Colesevelam HclColesevelam Hcl27suppressed
NystatinNystatin27suppressed
Bisoprolol-HydrochlorothiazideBisoprolol/Hydrochlorothiazide26suppressed
FluconazoleFluconazole2614
Lisinopril-HydrochlorothiazideLisinopril/Hydrochlorothiazide23suppressed
Tizanidine HclTizanidine Hcl2311
Ventolin HfaAlbuterol Sulfate2311
CholestyramineCholestyramine (With Sugar)22suppressed
JardianceEmpagliflozin22suppressed
Citalopram HbrCitalopram Hydrobromide21suppressed
FinasterideFinasteride21suppressed
Fluoxetine HclFluoxetine Hcl21suppressed
Glipizide ErGlipizide21suppressed
Clorazepate DipotassiumClorazepate Dipotassium20suppressed
Solifenacin SuccinateSolifenacin Succinate20suppressed
Lantus SolostarInsulin Glargine,hum.Rec.Anlog19suppressed
LevofloxacinLevofloxacin1916
NitroglycerinNitroglycerin1913
TopiramateTopiramate19suppressed
Breztri AerosphereBudesonide/Glycopyr/Formoterol18suppressed
Esomeprazole MagnesiumEsomeprazole Magnesium18suppressed
FentanylFentanyl18suppressed
Nifedipine ErNifedipine18suppressed
SpironolactoneSpironolactone18suppressed
Triamterene-HydrochlorothiazidTriamterene/Hydrochlorothiazid18suppressed
Amitriptyline HclAmitriptyline Hcl17suppressed
Budesonide-Formoterol FumarateBudesonide/Formoterol Fumarate17suppressed
TrulicityDulaglutide17suppressed
Donepezil HclDonepezil Hcl16suppressed
Losartan-HydrochlorothiazideLosartan/Hydrochlorothiazide16suppressed
Benazepril HclBenazepril Hcl15suppressed
Clotrimazole-BetamethasoneClotrimazole/Betamethasone Dip15suppressed
Testosterone CypionateTestosterone Cypionate15suppressed
CephalexinCephalexin14suppressed
Hydroxyzine HclHydroxyzine Hcl1411
MupirocinMupirocin1412
Oxybutynin Chloride ErOxybutynin Chloride14suppressed
Propranolol Hcl ErPropranolol Hcl14suppressed
Breo ElliptaFluticasone/Vilanterol13suppressed
Butalbital-Acetaminophen-CaffeButalb/Acetaminophen/Caffeine13suppressed
Ciprofloxacin HclCiprofloxacin Hcl13suppressed
HydrocortisoneHydrocortisone1311
Lithium CarbonateLithium Carbonate13suppressed
Oxybutynin ChlorideOxybutynin Chloride13suppressed
Triamcinolone AcetonideTriamcinolone Acetonide13suppressed
Ultra-Fine Nano Pen NeedlePen Needle, Diabetic13suppressed
Warfarin SodiumWarfarin Sodium13suppressed
Azelastine HclAzelastine Hcl12suppressed
CelecoxibCelecoxib12suppressed
Fluticasone-SalmeterolFluticasone Propion/Salmeterol12suppressed
GemfibrozilGemfibrozil12suppressed
Levocetirizine DihydrochlorideLevocetirizine Dihydrochloride12suppressed
TorsemideTorsemide12suppressed
Meclizine HclMeclizine Hcl11suppressed
Qvar RedihalerBeclomethasone Dipropionate11suppressed
Trelegy ElliptaFluticasone/Umeclidin/Vilanter11suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $83.86 · 3 records Lilly USA, LLC Ozempic 3
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error