Payment overview · 2025
General Payments
$2,738.70
149 reported records · 14 companies
Healthcare provider profile · identity verified
Mark Allen Esche, M.D.
Allopathic & Osteopathic Physicians|Psychiatry & Neurology|Psychiatry · AUSTIN, TX · NPI 1174622740
Verified facts
What the public records show
CMS Open Payments records show Mark Allen Esche, M.D. received $2,738.70 in general payments during 2025 across 149 reported records.
Alkermes, Inc. accounted for 26.4% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 20 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Auvelity, Azstarys, Ingrezza, Lybalvi, Rexulti, Sunosi, Trintellix, Vraylar.
ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported VRAYLAR as an associated drug or biological on 377741 records involving 62704 distinct recipient NPIs. Public Medicare Part D data also shows 63 claims for Vraylar by this doctor in 2024.
Alkermes, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LYBALVI as an associated drug or biological on 93784 records involving 20135 distinct recipient NPIs. Public Medicare Part D data also shows 12 claims for Lybalvi by this doctor in 2024.
Axsome Therapeutics, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Auvelity as an associated drug or biological on 116023 records involving 35298 distinct recipient NPIs. Public Medicare Part D data also shows 20 claims for Auvelity by this doctor in 2024.
Axsome Therapeutics, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Sunosi as an associated drug or biological on 19758 records involving 6305 distinct recipient NPIs. Public Medicare Part D data also shows 22 claims for Sunosi by this doctor in 2024.
Corium, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Azstarys as an associated drug or biological on 54930 records involving 15827 distinct recipient NPIs. Public Medicare Part D data also shows 29 claims for Azstarys by this doctor in 2024.
Lundbeck LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported REXULTI as an associated drug or biological on 71829 records involving 25812 distinct recipient NPIs. Public Medicare Part D data also shows 64 claims for Rexulti by this doctor in 2024.
Neurocrine BioSciences, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported INGREZZA as an associated drug or biological on 126456 records involving 27390 distinct recipient NPIs. Public Medicare Part D data also shows 33 claims for Ingrezza by this doctor in 2024.
Otsuka America Pharmaceutical, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported REXULTI as an associated drug or biological on 160756 records involving 46288 distinct recipient NPIs. Public Medicare Part D data also shows 64 claims for Rexulti by this doctor in 2024.
Takeda Pharmaceuticals U.S.A., Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRINTELLIX as an associated drug or biological on 37075 records involving 14402 distinct recipient NPIs. Public Medicare Part D data also shows 82 claims for Trintellix by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Alkermes, Inc. | Unresolved — no canonical attribution shown | $722.22 | 26.4% | 42 | 2025 |
| ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) | Unresolved — no canonical attribution shown | $497.44 | 18.2% | 24 | 2025 |
| Otsuka America Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $356.99 | 13.0% | 18 | 2025 |
| ABBVIE INC. | Unresolved — no canonical attribution shown | $306.78 | 11.2% | 20 | 2025 |
| Takeda Pharmaceuticals U.S.A., Inc. | Unresolved — no canonical attribution shown | $186.74 | 6.8% | 12 | 2025 |
| Axsome Therapeutics, Inc. | Unresolved — no canonical attribution shown | $172.65 | 6.3% | 8 | 2025 |
| Lundbeck LLC | Unresolved — no canonical attribution shown | $132.61 | 4.8% | 7 | 2025 |
| Neurocrine BioSciences, Inc. | Unresolved — no canonical attribution shown | $94.76 | 3.5% | 5 | 2025 |
| Collegium Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $78.84 | 2.9% | 5 | 2025 |
| Teva Pharmaceuticals USA, Inc. | Unresolved — no canonical attribution shown | $78.02 | 2.9% | 3 | 2025 |
| Noven Therapeutics, LLC | Unresolved — no canonical attribution shown | $41.51 | 1.5% | 2 | 2025 |
| ACADIA Pharmaceuticals Inc | Unresolved — no canonical attribution shown | $27.18 | 1.0% | 1 | 2025 |
| Corium, LLC | Unresolved — no canonical attribution shown | $24.98 | 0.9% | 1 | 2025 |
| E.R. Squibb & Sons, L.L.C. | Unresolved — no canonical attribution shown | $17.98 | 0.7% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $2,737.30 | 148 |
| Education | $1.40 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| ARISTADA Normalized: aristada |
Drug | Alkermes, Inc. | $654.77 | 39 | 2025 |
Source payment records
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| LYBALVI Normalized: lybalvi |
Drug | Alkermes, Inc. | $648.24 | 38 | 2025 |
Source payment records
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| CAPLYTA Normalized: caplyta |
Drug | ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) | $497.44 | 24 | 2025 |
Source payment records
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| REXULTI Normalized: rexulti |
Drug | Lundbeck LLC, Otsuka America Pharmaceutical, Inc. | $338.05 | 17 | 2025 |
Source payment records
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| VRAYLAR Normalized: vraylar |
Drug | ABBVIE INC. | $306.78 | 20 | 2025 |
Source payment records
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| TRINTELLIX Normalized: trintellix |
Drug | Takeda Pharmaceuticals U.S.A., Inc. | $186.74 | 12 | 2025 |
Source payment records
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| Auvelity Normalized: auvelity |
Drug | Axsome Therapeutics, Inc. | $146.99 | 7 | 2025 |
Source payment records
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| ABILIFY ASIMTUFII Normalized: abilify asimtufii |
Drug | Otsuka America Pharmaceutical, Inc. | $131.79 | 7 | 2025 |
Source payment records
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| INGREZZA Normalized: ingrezza |
Drug | Neurocrine BioSciences, Inc. | $94.76 | 5 | 2025 |
Source payment records
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| Jornay PM Normalized: jornay pm |
Drug | Collegium Pharmaceutical, Inc. | $78.84 | 5 | 2025 |
Source payment records
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| ARISTADA INITIO Normalized: aristada initio |
Drug | Alkermes, Inc. | $73.98 | 4 | 2025 |
Source payment records
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| Secuado Normalized: secuado |
Drug | Noven Therapeutics, LLC | $41.51 | 2 | 2025 |
Source payment records
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| Xelstrym Normalized: xelstrym |
Drug | Noven Therapeutics, LLC | $41.51 | 2 | 2025 |
Source payment records
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| UZEDY Normalized: uzedy |
Drug | Teva Pharmaceuticals USA, Inc. | $39.81 | 1 | 2025 |
Source payment records
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| AUSTEDO XR Normalized: austedo xr |
Drug | Teva Pharmaceuticals USA, Inc. | $38.21 | 2 | 2025 |
Source payment records
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| NUPLAZID Normalized: nuplazid |
Drug | ACADIA Pharmaceuticals Inc | $27.18 | 1 | 2025 |
Source payment records
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| Sunosi Normalized: sunosi |
Drug | Axsome Therapeutics, Inc. | $25.66 | 1 | 2025 |
Source payment records
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| Azstarys Normalized: azstarys |
Drug | Corium, LLC | $24.98 | 1 | 2025 |
Source payment records
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| ABILIFY MAINTENA Normalized: abilify maintena |
Drug | Otsuka America Pharmaceutical, Inc. | $19.76 | 1 | 2025 |
Source payment records
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| COBENFY Normalized: cobenfy |
Drug | E.R. Squibb & Sons, L.L.C. | $17.98 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| Auvelity auvelity |
2025 | Auvelity | 2024 | 20 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| Azstarys azstarys |
2025 | Azstarys | 2024 | 29 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| INGREZZA ingrezza |
2025 | Ingrezza | 2024 | 33 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| LYBALVI lybalvi |
2025 | Lybalvi | 2024 | 12 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| REXULTI rexulti |
2025 | Rexulti | 2024 | 64 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| Sunosi sunosi |
2025 | Sunosi | 2024 | 22 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| TRINTELLIX trintellix |
2025 | Trintellix | 2024 | 82 | exact normalized | Medicare Part D |
| VRAYLAR vraylar |
2025 | Vraylar | 2024 | 63 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| ABBVIE INC. Exact reporting entity; no affiliate inference |
2025 | VRAYLAR open payments reported associated product |
CMS Open Payments — General Payments 377741 supporting records · 62704 recipient NPIs · example record 1201352550 |
Vraylar · 2024 Exact normalized brand match · 1 Part D row |
63 | suppressed by CMS |
| Alkermes, Inc. Exact reporting entity; no affiliate inference |
2025 | LYBALVI open payments reported associated product |
CMS Open Payments — General Payments 93784 supporting records · 20135 recipient NPIs · example record 1222428566 |
Lybalvi · 2024 Exact normalized brand match · 1 Part D row |
12 | suppressed by CMS |
| Axsome Therapeutics, Inc. Exact reporting entity; no affiliate inference |
2025 | Auvelity open payments reported associated product |
CMS Open Payments — General Payments 116023 supporting records · 35298 recipient NPIs · example record 1235293064 |
Auvelity · 2024 Exact normalized brand match · 1 Part D row |
20 | suppressed by CMS |
| Axsome Therapeutics, Inc. Exact reporting entity; no affiliate inference |
2025 | Sunosi open payments reported associated product |
CMS Open Payments — General Payments 19758 supporting records · 6305 recipient NPIs · example record 1235293059 |
Sunosi · 2024 Exact normalized brand match · 1 Part D row |
22 | suppressed by CMS |
| Corium, LLC Exact reporting entity; no affiliate inference |
2025 | Azstarys open payments reported associated product |
CMS Open Payments — General Payments 54930 supporting records · 15827 recipient NPIs · example record 1185762907 |
Azstarys · 2024 Exact normalized brand match · 1 Part D row |
29 | suppressed by CMS |
| Lundbeck LLC Exact reporting entity; no affiliate inference |
2025 | REXULTI open payments reported associated product |
CMS Open Payments — General Payments 71829 supporting records · 25812 recipient NPIs · example record 1251759986 |
Rexulti · 2024 Exact normalized brand match · 1 Part D row |
64 | suppressed by CMS |
| Neurocrine BioSciences, Inc. Exact reporting entity; no affiliate inference |
2025 | INGREZZA open payments reported associated product |
CMS Open Payments — General Payments 126456 supporting records · 27390 recipient NPIs · example record 1242766729 |
Ingrezza · 2024 Exact normalized brand match · 1 Part D row |
33 | suppressed by CMS |
| Otsuka America Pharmaceutical, Inc. Exact reporting entity; no affiliate inference |
2025 | REXULTI open payments reported associated product |
CMS Open Payments — General Payments 160756 supporting records · 46288 recipient NPIs · example record 1227267708 |
Rexulti · 2024 Exact normalized brand match · 1 Part D row |
64 | suppressed by CMS |
| Takeda Pharmaceuticals U.S.A., Inc. Exact reporting entity; no affiliate inference |
2025 | TRINTELLIX open payments reported associated product |
CMS Open Payments — General Payments 37075 supporting records · 14402 recipient NPIs · example record 1223616266 |
Trintellix · 2024 Exact normalized brand match · 1 Part D row |
82 | 15 |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Alprazolam | Alprazolam | 327 | 56 |
| Clonazepam | Clonazepam | 220 | 38 |
| Dextroamphetamine-Amphetamine | Dextroamphetamine/Amphetamine | 184 | 22 |
| Lorazepam | Lorazepam | 165 | 24 |
| Lamotrigine | Lamotrigine | 151 | 34 |
| Trazodone Hcl | Trazodone Hcl | 149 | 27 |
| Duloxetine Hcl | Duloxetine Hcl | 130 | 25 |
| Bupropion Xl | Bupropion Hcl | 126 | 29 |
| Diazepam | Diazepam | 115 | 18 |
| Quetiapine Fumarate | Quetiapine Fumarate | 91 | 18 |
| Gabapentin | Gabapentin | 90 | 22 |
| Olanzapine | Olanzapine | 90 | 17 |
| Trintellix | Vortioxetine Hydrobromide | 82 | 15 |
| Escitalopram Oxalate | Escitalopram Oxalate | 81 | 20 |
| Aripiprazole | Aripiprazole | 80 | 20 |
| Lisdexamfetamine Dimesylate | Lisdexamfetamine Dimesylate | 71 | 18 |
| Sertraline Hcl | Sertraline Hcl | 66 | 16 |
| Rexulti | Brexpiprazole | 64 | suppressed |
| Vraylar | Cariprazine Hcl | 63 | suppressed |
| Dexmethylphenidate Hcl Er | Dexmethylphenidate Hcl | 62 | suppressed |
| Vilazodone Hcl | Vilazodone Hcl | 62 | 13 |
| Belsomra | Suvorexant | 50 | suppressed |
| Zolpidem Tartrate Er | Zolpidem Tartrate | 47 | suppressed |
| Vyvanse | Lisdexamfetamine Dimesylate | 46 | 11 |
| Desvenlafaxine Succinate Er | Desvenlafaxine Succinate | 44 | suppressed |
| Eszopiclone | Eszopiclone | 44 | 11 |
| Methylphenidate Er | Methylphenidate Hcl | 42 | suppressed |
| Methylphenidate Hcl | Methylphenidate Hcl | 42 | suppressed |
| Zolpidem Tartrate | Zolpidem Tartrate | 41 | suppressed |
| Dextroamphetamine-Amphet Er | Dextroamphetamine/Amphetamine | 37 | suppressed |
| Divalproex Sodium Er | Divalproex Sodium | 36 | suppressed |
| Fluoxetine Hcl | Fluoxetine Hcl | 34 | suppressed |
| Ingrezza | Valbenazine Tosylate | 33 | suppressed |
| Lithium Carbonate Er | Lithium Carbonate | 32 | suppressed |
| Azstarys | Serdexmethylphen/Dexmethylphen | 29 | suppressed |
| Metoprolol Succinate | Metoprolol Succinate | 29 | suppressed |
| Hydroxyzine Pamoate | Hydroxyzine Pamoate | 28 | suppressed |
| Baclofen | Baclofen | 25 | suppressed |
| Bupropion Hcl Sr | Bupropion Hcl | 24 | suppressed |
| Nortriptyline Hcl | Nortriptyline Hcl | 24 | suppressed |
| Dextroamphetamine Sulfate Er | Dextroamphetamine Sulfate | 23 | suppressed |
| Haloperidol | Haloperidol | 23 | suppressed |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 22 | suppressed |
| Sunosi | Solriamfetol Hcl | 22 | suppressed |
| Quetiapine Fumarate Er | Quetiapine Fumarate | 21 | suppressed |
| Auvelity | Dextromethorphan Hbr/Bupropion | 20 | suppressed |
| Dexmethylphenidate Hcl | Dexmethylphenidate Hcl | 20 | suppressed |
| Zaleplon | Zaleplon | 19 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 17 | suppressed |
| Dextroamphetamine Sulfate | Dextroamphetamine Sulfate | 16 | suppressed |
| Venlafaxine Hcl Er | Venlafaxine Hcl | 16 | suppressed |
| Asenapine Maleate | Asenapine Maleate | 14 | suppressed |
| Dayvigo | Lemborexant | 14 | suppressed |
| Chlorpromazine Hcl | Chlorpromazine Hcl | 13 | suppressed |
| Clozapine | Clozapine | 13 | suppressed |
| Pregabalin | Pregabalin | 13 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 13 | suppressed |
| Guanfacine Hcl | Guanfacine Hcl | 12 | suppressed |
| Guanfacine Hcl Er | Guanfacine Hcl | 12 | suppressed |
| Lybalvi | Olanzapine/Samidorphan Malate | 12 | suppressed |
| Methylphenidate Er (La) | Methylphenidate Hcl | 12 | suppressed |
| Mirtazapine | Mirtazapine | 12 | suppressed |
| Olanzapine-Fluoxetine Hcl | Olanzapine/Fluoxetine Hcl | 12 | suppressed |
| Butalbital-Acetaminophen-Caffe | Butalb/Acetaminophen/Caffeine | 11 | suppressed |
| Dyanavel Xr | Amphetamine | 11 | suppressed |
| Latuda | Lurasidone Hcl | 11 | suppressed |
| Mydayis | Dextroamphetamine/Amphetamine | 11 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 11 | suppressed |
| Ramelteon | Ramelteon | 11 | suppressed |
| Risperidone | Risperidone | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $2,738.70 · 149 records | Alkermes, Inc. | ABILIFY ASIMTUFII, ABILIFY MAINTENA, ARISTADA, ARISTADA INITIO, AUSTEDO XR, Auvelity, Azstarys, CAPLYTA, COBENFY, INGREZZA, Jornay PM, LYBALVI, NUPLAZID, REXULTI, Secuado, Sunosi, TRINTELLIX, UZEDY, VRAYLAR, Xelstrym | 9 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Auvelity play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with ABBVIE INC.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error