Payment overview · 2025
General Payments
$1,891.02
70 reported records · 19 companies
Healthcare provider profile · identity verified
Ann Renee Manuel
Physician Assistants & Advanced Practice Nursing Providers|Nurse Practitioner|Family · SHENANDOAH, TX · NPI 1225514524
Verified facts
What the public records show
CMS Open Payments records show Ann Renee Manuel received $1,891.02 in general payments during 2025 across 70 reported records.
Medtronic, Inc. accounted for 17.2% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 26 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Eliquis.
E.R. Squibb & Sons, L.L.C. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 27956 records involving 14870 distinct recipient NPIs. Public Medicare Part D data also shows 210 claims for Eliquis by this doctor in 2024.
Novartis Pharmaceuticals Corporation reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ENTRESTO as an associated drug or biological on 9346 records involving 6254 distinct recipient NPIs. Public Medicare Part D data also shows 19 claims for Entresto by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Medtronic, Inc. |
Medtronic, Inc. exact · evidence 2025-07-22 |
$325.31 | 17.2% | 6 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $296.16 | 15.7% | 19 | 2025 |
| Abbott Laboratories | Unresolved — no canonical attribution shown | $283.14 | 15.0% | 5 | 2025 |
| Boston Scientific Corporation | Unresolved — no canonical attribution shown | $207.66 | 11.0% | 10 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $161.15 | 8.5% | 6 | 2025 |
| E.R. Squibb & Sons, L.L.C. | Unresolved — no canonical attribution shown | $145.31 | 7.7% | 7 | 2025 |
| ABIOMED | Unresolved — no canonical attribution shown | $138.10 | 7.3% | 1 | 2025 |
| Actelion Pharmaceuticals US, Inc. | Unresolved — no canonical attribution shown | $85.43 | 4.5% | 3 | 2025 |
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $36.51 | 1.9% | 2 | 2025 |
| AtriCure, Inc. | Unresolved — no canonical attribution shown | $36.06 | 1.9% | 1 | 2025 |
| ZOLL Services LLC (A/K/A ZOLL LifeCor Corp) | Unresolved — no canonical attribution shown | $26.81 | 1.4% | 2 | 2025 |
| Boehringer Ingelheim Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $22.98 | 1.2% | 1 | 2025 |
| Smith+Nephew, Inc. | Unresolved — no canonical attribution shown | $21.87 | 1.2% | 1 | 2025 |
| Edwards Lifesciences Corporation | Unresolved — no canonical attribution shown | $21.28 | 1.1% | 1 | 2025 |
| Merck Sharp & Dohme LLC | Unresolved — no canonical attribution shown | $19.85 | 1.1% | 1 | 2025 |
| Inspire Medical Systems, Inc. | Unresolved — no canonical attribution shown | $18.27 | 1.0% | 1 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $15.75 | 0.8% | 1 | 2025 |
| Kaneka Medical America LLC | Unresolved — no canonical attribution shown | $15.31 | 0.8% | 1 | 2025 |
| HEARTFLOW, INC. | Unresolved — no canonical attribution shown | $14.07 | 0.7% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $1,891.02 | 70 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| LEQVIO Normalized: leqvio |
Drug | Novartis Pharmaceuticals Corporation | $296.16 | 19 | 2025 |
Source payment records
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| HAWKONE Normalized: hawkone |
Device | Medtronic, Inc. | $243.79 | 3 | 2025 |
Source payment records
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| CARDIOMEMS Normalized: cardiomems |
Device | Abbott Laboratories | $169.00 | 3 | 2025 |
Source payment records
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| REPATHA Normalized: repatha |
Biological | Amgen Inc. | $152.97 | 4 | 2025 |
Source payment records
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| WATCHMAN FLX Normalized: watchman flx |
Device | Boston Scientific Corporation | $136.11 | 4 | 2025 |
Source payment records
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| AMPLATZER AMULET Normalized: amplatzer amulet |
Device | Abbott Laboratories | $98.90 | 1 | 2025 |
Source payment records
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| OPSUMIT Normalized: opsumit |
Drug | Actelion Pharmaceuticals US, Inc. | $85.43 | 3 | 2025 |
Source payment records
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| UPTRAVI Normalized: uptravi |
Drug | Actelion Pharmaceuticals US, Inc. | $85.43 | 3 | 2025 |
Source payment records
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| ELIQUIS Normalized: eliquis |
Drug | E.R. Squibb & Sons, L.L.C. | $80.14 | 4 | 2025 |
Source payment records
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| BodyGuardian Normalized: bodyguardian |
Device | Boston Scientific Corporation | $71.55 | 6 | 2025 |
Source payment records
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| CAMZYOS Normalized: camzyos |
Drug | E.R. Squibb & Sons, L.L.C. | $65.17 | 3 | 2025 |
Source payment records
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| PLASMABLADE(TM) Normalized: plasmablade tm |
Device | Medtronic, Inc. | $47.97 | 2 | 2025 |
Source payment records
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| WAINUA Normalized: wainua |
Drug | AstraZeneca Pharmaceuticals LP | $36.51 | 2 | 2025 |
Source payment records
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| SYNERGY ABLATION SYSTEM Normalized: synergy ablation system |
Device | AtriCure, Inc. | $36.06 | 1 | 2025 |
Source payment records
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| VENASEAL Normalized: venaseal |
Device | Medtronic, Inc. | $33.55 | 1 | 2025 |
Source payment records
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| LifeVest Normalized: lifevest |
Device | ZOLL Services LLC (A/K/A ZOLL LifeCor Corp) | $26.81 | 2 | 2025 |
Source payment records
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| JARDIANCE Normalized: jardiance |
Drug | Boehringer Ingelheim Pharmaceuticals, Inc. | $22.98 | 1 | 2025 |
Source payment records
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| RENASYS TOUCH Normalized: renasys touch |
Device | Smith+Nephew, Inc. | $21.87 | 1 | 2025 |
Source payment records
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| SAPIEN 3 Ultra RESILIA Normalized: sapien 3 ultra resilia |
Device | Edwards Lifesciences Corporation | $21.28 | 1 | 2025 |
Source payment records
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| CAPVAXIVE Normalized: capvaxive |
Biological | Merck Sharp & Dohme LLC | $19.85 | 1 | 2025 |
Source payment records
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| VERQUVO Normalized: verquvo |
Drug | Merck Sharp & Dohme LLC | $19.85 | 1 | 2025 |
Source payment records
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| INSPIRE Normalized: inspire |
Device | Inspire Medical Systems, Inc. | $18.27 | 1 | 2025 |
Source payment records
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| Kerendia Normalized: kerendia |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $15.75 | 1 | 2025 |
Source payment records
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| Apheresis Machine Normalized: apheresis machine |
Device | Kaneka Medical America LLC | $15.31 | 1 | 2025 |
Source payment records
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| AVEIR Normalized: aveir |
Device | Abbott Laboratories | $15.24 | 1 | 2025 |
Source payment records
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| FFRct Normalized: ffrct |
Device | HEARTFLOW, INC. | $14.07 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| ELIQUIS eliquis |
2025 | Eliquis | 2024 | 210 | exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| E.R. Squibb & Sons, L.L.C. Exact reporting entity; no affiliate inference |
2025 | ELIQUIS open payments reported associated product |
CMS Open Payments — General Payments 27956 supporting records · 14870 recipient NPIs · example record 1184377713 |
Eliquis · 2024 Exact normalized brand match · 1 Part D row |
210 | 63 |
| Novartis Pharmaceuticals Corporation Exact reporting entity; no affiliate inference |
2025 | ENTRESTO open payments reported associated product |
CMS Open Payments — General Payments 9346 supporting records · 6254 recipient NPIs · example record 1200004797 |
Entresto · 2024 Exact normalized brand match · 1 Part D row |
19 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Eliquis | Apixaban | 210 | 63 |
| Metoprolol Succinate | Metoprolol Succinate | 200 | 78 |
| Valsartan | Valsartan | 144 | 50 |
| Atorvastatin Calcium | Atorvastatin Calcium | 136 | 59 |
| Furosemide | Furosemide | 124 | 54 |
| Amlodipine Besylate | Amlodipine Besylate | 65 | 31 |
| Nifedipine Er | Nifedipine | 56 | 24 |
| Clopidogrel | Clopidogrel Bisulfate | 55 | 26 |
| Metoprolol Tartrate | Metoprolol Tartrate | 51 | 25 |
| Carvedilol | Carvedilol | 44 | 15 |
| Lisinopril | Lisinopril | 44 | 17 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 44 | 20 |
| Amiodarone Hcl | Amiodarone Hcl | 35 | 24 |
| Losartan Potassium | Losartan Potassium | 35 | 17 |
| Xarelto | Rivaroxaban | 32 | 12 |
| Isosorbide Mononitrate Er | Isosorbide Mononitrate | 28 | 15 |
| Repatha Sureclick | Evolocumab | 27 | suppressed |
| Ezetimibe | Ezetimibe | 21 | suppressed |
| Entresto | Sacubitril/Valsartan | 19 | suppressed |
| Clonidine Hcl | Clonidine Hcl | 17 | suppressed |
| Nebivolol Hcl | Nebivolol Hcl | 17 | suppressed |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 17 | suppressed |
| Potassium Chloride | Potassium Chloride | 15 | suppressed |
| Enalapril Maleate | Enalapril Maleate | 12 | suppressed |
| Spironolactone | Spironolactone | 12 | suppressed |
| Atenolol | Atenolol | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $1,891.02 · 70 records | Medtronic, Inc. | AMPLATZER AMULET, AVEIR, Apheresis Machine, BodyGuardian, CAMZYOS, CAPVAXIVE, CARDIOMEMS, ELIQUIS, FFRct, HAWKONE, INSPIRE, JARDIANCE, Kerendia, LEQVIO, LifeVest, OPSUMIT, PLASMABLADE(TM), RENASYS TOUCH, REPATHA, SAPIEN 3 Ultra RESILIA, SYNERGY ABLATION SYSTEM, UPTRAVI, VENASEAL, VERQUVO, WAINUA, WATCHMAN FLX | 2 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Eliquis play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with E.R. Squibb & Sons, L.L.C.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error