Healthcare provider profile · identity verified

Karla Rene Smith, MD

Allopathic & Osteopathic Physicians|Family Medicine · HIGH POINT, NC · NPI 1275663593

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Karla Rene Smith, MD received $836.48 in general payments during 2025 across 54 reported records.

ABBVIE INC. accounted for 35.1% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 22 associated products.

A separate comparison found the same explicitly named product in public Medicare Part D data: Eliquis, Jardiance, Mounjaro.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LINZESS as an associated drug or biological on 87954 records involving 21815 distinct recipient NPIs. Public Medicare Part D data also shows 76 claims for Linzess by this doctor in 2024.

AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported FARXIGA as an associated drug or biological on 106133 records involving 42906 distinct recipient NPIs. Public Medicare Part D data also shows 37 claims for Farxiga by this doctor in 2024.

AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYMBICORT as an associated drug or biological on 71 records involving 51 distinct recipient NPIs. Public Medicare Part D data also shows 30 claims for Symbicort by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported JARDIANCE as an associated drug or biological on 47708 records involving 23833 distinct recipient NPIs. Public Medicare Part D data also shows 26 claims for Jardiance by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported MOUNJARO as an associated drug or biological on 186719 records involving 66436 distinct recipient NPIs. Public Medicare Part D data also shows 109 claims for Mounjaro by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRULICITY as an associated drug or biological on 71 records involving 57 distinct recipient NPIs. Public Medicare Part D data also shows 38 claims for Trulicity by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 77 claims for Ozempic by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Rybelsus as an associated drug or biological on 161257 records involving 55409 distinct recipient NPIs. Public Medicare Part D data also shows 46 claims for Rybelsus by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 87112 records involving 36032 distinct recipient NPIs. Public Medicare Part D data also shows 80 claims for Eliquis by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$836.48

54 reported records · 16 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
ABBVIE INC. Unresolved — no canonical attribution shown $293.7935.1%252025
Lilly USA, LLC Unresolved — no canonical attribution shown $109.1313.1%62025
PFIZER INC. Unresolved — no canonical attribution shown $60.917.3%42025
Lundbeck LLC Unresolved — no canonical attribution shown $58.006.9%22025
Novartis Pharmaceuticals Corporation Unresolved — no canonical attribution shown $42.595.1%22025
SHIELD THERAPEUTICS INC Unresolved — no canonical attribution shown $40.044.8%22025
AstraZeneca Pharmaceuticals LP Unresolved — no canonical attribution shown $33.494.0%22025
VERTEX PHARMACEUTICALS INCORPORATED Unresolved — no canonical attribution shown $32.803.9%22025
Astellas Pharma US Inc Unresolved — no canonical attribution shown $29.853.6%22025
Dexcom, Inc. Unresolved — no canonical attribution shown $28.613.4%12025
Neurocrine BioSciences, Inc. Unresolved — no canonical attribution shown $23.812.9%12025
Abbott Laboratories Unresolved — no canonical attribution shown $19.472.3%12025
Exact Sciences Corporation Unresolved — no canonical attribution shown $18.532.2%12025
Novo Nordisk Inc Unresolved — no canonical attribution shown $16.462.0%12025
Amgen Inc. Unresolved — no canonical attribution shown $14.811.8%12025
Salix Pharmaceuticals, a division of Bausch Health US, LLC Unresolved — no canonical attribution shown $14.191.7%12025

What were the payments for?

Payment categories

CategoryAmountRecords
Food and Beverage$836.4854

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
QULIPTA
Normalized: qulipta
Drug ABBVIE INC. $258.07 23 2025
Source payment records
UBRELVY
Normalized: ubrelvy
Drug ABBVIE INC. $258.07 23 2025
Source payment records
ZEPBOUND
Normalized: zepbound
Drug Lilly USA, LLC $70.72 4 2025
Source payment records
MOUNJARO
Normalized: mounjaro
Drug Lilly USA, LLC $69.16 4 2025
Source payment records
NURTEC ODT
Normalized: nurtec odt
Drug PFIZER INC. $60.91 4 2025
Source payment records
VYEPTI
Normalized: vyepti
Biological Lundbeck LLC $58.00 2 2025
Source payment records
ZAVZPRET
Normalized: zavzpret
Drug PFIZER INC. $45.75 3 2025
Source payment records
ACCRUFER
Normalized: accrufer
Drug SHIELD THERAPEUTICS INC $40.04 2 2025
Source payment records
VRAYLAR
Normalized: vraylar
Drug ABBVIE INC. $35.72 2 2025
Source payment records
BREZTRI
Normalized: breztri
Drug AstraZeneca Pharmaceuticals LP $33.49 2 2025
Source payment records
ALYFTREK
Normalized: alyftrek
Drug VERTEX PHARMACEUTICALS INCORPORATED $32.80 2 2025
Source payment records
Veozah
Normalized: veozah
Drug Astellas Pharma US Inc $29.85 2 2025
Source payment records
Dexcom G6 Transmitter
Normalized: dexcom g6 transmitter
Medical Supply Dexcom, Inc. $28.61 1 2025
Source payment records
INGREZZA
Normalized: ingrezza
Drug Neurocrine BioSciences, Inc. $23.81 1 2025
Source payment records
JARDIANCE
Normalized: jardiance
Drug Lilly USA, LLC $21.28 1 2025
Source payment records
FREESTYLE LIBRE 3
Normalized: freestyle libre 3
Device Abbott Laboratories $19.47 1 2025
Source payment records
The Cologuard Plus Collection Kit
Normalized: the cologuard plus collection kit
Device Exact Sciences Corporation $18.53 1 2025
Source payment records
Wegovy
Normalized: wegovy
Drug Novo Nordisk Inc $16.46 1 2025
Source payment records
ELIQUIS
Normalized: eliquis
Drug PFIZER INC. $15.16 1 2025
Source payment records
OTEZLA
Normalized: otezla
Drug Amgen Inc. $14.81 1 2025
Source payment records
REPATHA
Normalized: repatha
Biological Amgen Inc. $14.81 1 2025
Source payment records
XIFAXAN
Normalized: xifaxan
Drug Salix Pharmaceuticals, a division of Bausch Health US, LLC $14.19 1 2025
Source payment records
  • 2025-03-13 · Salix Pharmaceuticals, a division of Bausch Health US, LLC · $14.19 · Open Payments source

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
ELIQUIS
eliquis
2025 Eliquis 2024 80 exact normalized Medicare Part D
JARDIANCE
jardiance
2025 Jardiance 2024 26
Beneficiary count suppressed
exact normalized Medicare Part D
MOUNJARO
mounjaro
2025 Mounjaro 2024 109 exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 LINZESS
open payments reported associated product
CMS Open Payments — General Payments
87954 supporting records · 21815 recipient NPIs · example record 1201352608
Linzess · 2024
Exact normalized brand match · 1 Part D row
76 22
AstraZeneca Pharmaceuticals LP
Exact reporting entity; no affiliate inference
2025 FARXIGA
open payments reported associated product
CMS Open Payments — General Payments
106133 supporting records · 42906 recipient NPIs · example record 1206131362
Farxiga · 2024
Exact normalized brand match · 1 Part D row
37 suppressed by CMS
AstraZeneca Pharmaceuticals LP
Exact reporting entity; no affiliate inference
2025 SYMBICORT
open payments reported associated product
CMS Open Payments — General Payments
71 supporting records · 51 recipient NPIs · example record 1206132610
Symbicort · 2024
Exact normalized brand match · 1 Part D row
30 suppressed by CMS
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 JARDIANCE
open payments reported associated product
CMS Open Payments — General Payments
47708 supporting records · 23833 recipient NPIs · example record 1186464557
Jardiance · 2024
Exact normalized brand match · 1 Part D row
26 suppressed by CMS
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 MOUNJARO
open payments reported associated product
CMS Open Payments — General Payments
186719 supporting records · 66436 recipient NPIs · example record 1186464455
Mounjaro · 2024
Exact normalized brand match · 1 Part D row
109 18
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 TRULICITY
open payments reported associated product
CMS Open Payments — General Payments
71 supporting records · 57 recipient NPIs · example record 1186464601
Trulicity · 2024
Exact normalized brand match · 1 Part D row
38 11
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Ozempic
open payments reported associated product
CMS Open Payments — General Payments
261625 supporting records · 77793 recipient NPIs · example record 1188130076
Ozempic · 2024
Exact normalized brand match · 1 Part D row
77 19
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Rybelsus
open payments reported associated product
CMS Open Payments — General Payments
161257 supporting records · 55409 recipient NPIs · example record 1188130076
Rybelsus · 2024
Exact normalized brand match · 1 Part D row
46 11
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 ELIQUIS
open payments reported associated product
CMS Open Payments — General Payments
87112 supporting records · 36032 recipient NPIs · example record 1228794063
Eliquis · 2024
Exact normalized brand match · 1 Part D row
80 14

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Atorvastatin CalciumAtorvastatin Calcium547159
Amlodipine BesylateAmlodipine Besylate362105
Hydrocodone-AcetaminophenHydrocodone/Acetaminophen23243
Levothyroxine SodiumLevothyroxine Sodium20855
LisinoprilLisinopril18552
Rosuvastatin CalciumRosuvastatin Calcium17153
Fluticasone PropionateFluticasone Propionate16863
Losartan PotassiumLosartan Potassium16646
GabapentinGabapentin14847
Metformin HclMetformin Hcl14845
PregabalinPregabalin13332
HydrochlorothiazideHydrochlorothiazide12838
Oxycodone-AcetaminophenOxycodone Hcl/Acetaminophen12124
Pantoprazole SodiumPantoprazole Sodium11935
MounjaroTirzepatide10918
Potassium ChloridePotassium Chloride10540
SimvastatinSimvastatin10532
OmeprazoleOmeprazole10436
Albuterol Sulfate HfaAlbuterol Sulfate10233
Montelukast SodiumMontelukast Sodium9834
Zolpidem TartrateZolpidem Tartrate9718
Losartan-HydrochlorothiazideLosartan/Hydrochlorothiazide8927
Metoprolol SuccinateMetoprolol Succinate8425
Metformin Hcl ErMetformin Hcl8328
FurosemideFurosemide8224
Cyclobenzaprine HclCyclobenzaprine Hcl8020
EliquisApixaban8014
Oxycodone HclOxycodone Hcl7913
OzempicSemaglutide7719
LinzessLinaclotide7622
Pravastatin SodiumPravastatin Sodium7422
Lisinopril-HydrochlorothiazideLisinopril/Hydrochlorothiazide7322
Tramadol HclTramadol Hcl7117
LorazepamLorazepam7011
Triamcinolone AcetonideTriamcinolone Acetonide5920
Sertraline HclSertraline Hcl5617
Alendronate SodiumAlendronate Sodium5113
AlprazolamAlprazolam5112
JanuviaSitagliptin Phosphate50suppressed
Meclizine HclMeclizine Hcl4915
Doxycycline HyclateDoxycycline Hyclate4840
RybelsusSemaglutide4611
Trazodone HclTrazodone Hcl4615
CarvedilolCarvedilol4515
Triamterene-HydrochlorothiazidTriamterene/Hydrochlorothiazid4312
AllopurinolAllopurinol4214
EzetimibeEzetimibe4218
Vitamin D2Ergocalciferol (Vitamin D2)3913
TrulicityDulaglutide3811
Duloxetine HclDuloxetine Hcl3714
FarxigaDapagliflozin Propanediol37suppressed
ClonazepamClonazepam36suppressed
Fluoxetine HclFluoxetine Hcl36suppressed
Metoprolol TartrateMetoprolol Tartrate3612
Valsartan-HydrochlorothiazideValsartan/Hydrochlorothiazide34suppressed
XareltoRivaroxaban34suppressed
PrednisonePrednisone3324
FluconazoleFluconazole3218
MeloxicamMeloxicam32suppressed
Esomeprazole MagnesiumEsomeprazole Magnesium3113
Ondansetron HclOndansetron Hcl3011
SymbicortBudesonide/Formoterol Fumarate30suppressed
Citalopram HbrCitalopram Hydrobromide29suppressed
Clonidine HclClonidine Hcl29suppressed
ClopidogrelClopidogrel Bisulfate29suppressed
FamotidineFamotidine2912
SpironolactoneSpironolactone28suppressed
AtenololAtenolol26suppressed
Hydralazine HclHydralazine Hcl26suppressed
JardianceEmpagliflozin26suppressed
Tizanidine HclTizanidine Hcl2512
EstradiolEstradiol24suppressed
Nebivolol HclNebivolol Hcl24suppressed
Escitalopram OxalateEscitalopram Oxalate23suppressed
Klor-Con M20Potassium Chloride23suppressed
MirtazapineMirtazapine23suppressed
BaclofenBaclofen22suppressed
Hydroxyzine HclHydroxyzine Hcl22suppressed
Olmesartan MedoxomilOlmesartan Medoxomil21suppressed
Lantus SolostarInsulin Glargine,hum.Rec.Anlog20suppressed
Olmesartan-HydrochlorothiazideOlmesartan/Hydrochlorothiazide20suppressed
CephalexinCephalexin1915
Trelegy ElliptaFluticasone/Umeclidin/Vilanter19suppressed
Venlafaxine Hcl ErVenlafaxine Hcl19suppressed
DiazepamDiazepam18suppressed
NexletolBempedoic Acid18suppressed
Breo ElliptaFluticasone/Vilanterol17suppressed
Glipizide ErGlipizide17suppressed
Propranolol HclPropranolol Hcl17suppressed
Novolin 70-30Insulin Nph Hum/Reg Insulin Hm16suppressed
CelecoxibCelecoxib15suppressed
Dexlansoprazole DrDexlansoprazole15suppressed
Irbesartan-HydrochlorothiazideIrbesartan/Hydrochlorothiazide15suppressed
LevetiracetamLevetiracetam15suppressed
Soliqua 100-33Insulin Glargine/Lixisenatide15suppressed
Tamsulosin HclTamsulosin Hcl15suppressed
FenofibrateFenofibrate,micronized14suppressed
Humalog Mix 75-25 KwikpenInsulin Lispro Protamin/Lispro14suppressed
Ipratropium BromideIpratropium Bromide14suppressed
Quetiapine FumarateQuetiapine Fumarate14suppressed
Buspirone HclBuspirone Hcl13suppressed
Folic AcidFolic Acid13suppressed
GlipizideGlipizide13suppressed
Nifedipine ErNifedipine13suppressed
OlanzapineOlanzapine13suppressed
Ondansetron OdtOndansetron13suppressed
OxcarbazepineOxcarbazepine13suppressed
Ventolin HfaAlbuterol Sulfate13suppressed
Wixela InhubFluticasone Propion/Salmeterol13suppressed
Xtampza ErOxycodone Myristate13suppressed
Amitriptyline HclAmitriptyline Hcl12suppressed
Amlodipine Besylate-BenazeprilAmlodipine Besylate/Benazepril12suppressed
BuprenorphineBuprenorphine12suppressed
Bupropion XlBupropion Hcl12suppressed
Butalbital-Acetaminophen-CaffeButalb/Acetaminophen/Caffeine12suppressed
Diclofenac SodiumDiclofenac Sodium12suppressed
GlimepirideGlimepiride12suppressed
OxycontinOxycodone Hcl12suppressed
Promethazine HclPromethazine Hcl12suppressed
Anoro ElliptaUmeclidinium Brm/Vilanterol Tr11suppressed
Diltiazem 24hr Er (Cd)Diltiazem Hcl11suppressed
HydrocortisoneHydrocortisone11suppressed
Hysingla ErHydrocodone Bitartrate11suppressed
Sildenafil CitrateSildenafil Citrate11suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $836.48 · 54 records ABBVIE INC. ACCRUFER, ALYFTREK, BREZTRI, Dexcom G6 Transmitter, ELIQUIS, FREESTYLE LIBRE 3, INGREZZA, JARDIANCE, MOUNJARO, NURTEC ODT, OTEZLA, QULIPTA, REPATHA, The Cologuard Plus Collection Kit, UBRELVY, VRAYLAR, VYEPTI, Veozah, Wegovy, XIFAXAN, ZAVZPRET, ZEPBOUND 9
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error