Payment overview · 2025
General Payments
4 reported records · 3 companies
Healthcare provider profile · identity verified
Allopathic & Osteopathic Physicians|Internal Medicine · KATY, TX · NPI 1306846043
Verified facts
CMS Open Payments records show David W. Reininger, M.D. received $152.84 in general payments during 2025 across 4 reported records.
ACADIA Pharmaceuticals Inc accounted for 73.4% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 3 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Nuplazid.
ACADIA Pharmaceuticals Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported NUPLAZID as an associated drug or biological on 20845 records involving 6448 distinct recipient NPIs. Public Medicare Part D data also shows 22 claims for Nuplazid by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Payment overview · 2025
4 reported records · 3 companies
Separate record types
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| ACADIA Pharmaceuticals Inc | Unresolved — no canonical attribution shown | $112.25 | 73.4% | 2 | 2025 |
| Otsuka America Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $20.91 | 13.7% | 1 | 2025 |
| Neurocrine BioSciences, Inc. | Unresolved — no canonical attribution shown | $19.68 | 12.9% | 1 | 2025 |
What were the payments for?
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $152.84 | 4 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| NUPLAZID Normalized: nuplazid |
Drug | ACADIA Pharmaceuticals Inc | $112.25 | 2 | 2025 |
Source payment records
|
|||||
| REXULTI Normalized: rexulti |
Drug | Otsuka America Pharmaceutical, Inc. | $20.91 | 1 | 2025 |
Source payment records
|
|||||
| INGREZZA Normalized: ingrezza |
Drug | Neurocrine BioSciences, Inc. | $19.68 | 1 | 2025 |
Source payment records
|
|||||
* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| NUPLAZID nuplazid |
2025 | Nuplazid | 2024 | 22 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| ACADIA Pharmaceuticals Inc Exact reporting entity; no affiliate inference |
2025 | NUPLAZID open payments reported associated product |
CMS Open Payments — General Payments 20845 supporting records · 6448 recipient NPIs · example record 1247763852 |
Nuplazid · 2024 Exact normalized brand match · 1 Part D row |
22 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Levothyroxine Sodium | Levothyroxine Sodium | 491 | 48 |
| Amlodipine Besylate | Amlodipine Besylate | 220 | 42 |
| Atorvastatin Calcium | Atorvastatin Calcium | 213 | 56 |
| Eliquis | Apixaban | 206 | 25 |
| Sertraline Hcl | Sertraline Hcl | 193 | 31 |
| Memantine Hcl | Memantine Hcl | 191 | 30 |
| Losartan Potassium | Losartan Potassium | 185 | 31 |
| Gabapentin | Gabapentin | 159 | 33 |
| Clopidogrel | Clopidogrel Bisulfate | 158 | 26 |
| Donepezil Hcl | Donepezil Hcl | 156 | 30 |
| Lisinopril | Lisinopril | 155 | 24 |
| Divalproex Sodium | Divalproex Sodium | 143 | 27 |
| Furosemide | Furosemide | 133 | 32 |
| Carvedilol | Carvedilol | 128 | 23 |
| Metoprolol Tartrate | Metoprolol Tartrate | 128 | 30 |
| Metoprolol Succinate | Metoprolol Succinate | 126 | 17 |
| Spironolactone | Spironolactone | 124 | 19 |
| Mirtazapine | Mirtazapine | 123 | 27 |
| Potassium Chloride | Potassium Chloride | 121 | 30 |
| Trazodone Hcl | Trazodone Hcl | 118 | 32 |
| Tamsulosin Hcl | Tamsulosin Hcl | 117 | 25 |
| Duloxetine Hcl | Duloxetine Hcl | 113 | 19 |
| Ipratropium-Albuterol | Ipratropium/Albuterol Sulfate | 111 | 34 |
| Hydralazine Hcl | Hydralazine Hcl | 102 | 19 |
| Levetiracetam | Levetiracetam | 96 | 17 |
| Baclofen | Baclofen | 92 | 13 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 92 | suppressed |
| Nifedipine Er | Nifedipine | 84 | 12 |
| Allopurinol | Allopurinol | 83 | suppressed |
| Buspirone Hcl | Buspirone Hcl | 75 | 21 |
| Pantoprazole Sodium | Pantoprazole Sodium | 75 | 18 |
| Omeprazole | Omeprazole | 74 | 17 |
| Lactulose | Lactulose | 73 | 21 |
| Carbidopa-Levodopa | Carbidopa/Levodopa | 72 | 14 |
| Amoxicillin | Amoxicillin | 65 | 11 |
| Fluoxetine Hcl | Fluoxetine Hcl | 64 | suppressed |
| Myrbetriq | Mirabegron | 63 | suppressed |
| Metformin Hcl | Metformin Hcl | 61 | 15 |
| Escitalopram Oxalate | Escitalopram Oxalate | 60 | 11 |
| Finasteride | Finasteride | 58 | suppressed |
| Latanoprost | Latanoprost | 53 | suppressed |
| Famotidine | Famotidine | 50 | 14 |
| Midodrine Hcl | Midodrine Hcl | 49 | suppressed |
| Amiodarone Hcl | Amiodarone Hcl | 45 | suppressed |
| Simvastatin | Simvastatin | 43 | suppressed |
| Ondansetron Hcl | Ondansetron Hcl | 42 | 18 |
| Quetiapine Fumarate | Quetiapine Fumarate | 39 | 13 |
| Valproic Acid | Valproic Acid (As Sodium Salt) | 39 | suppressed |
| Lumigan | Bimatoprost | 37 | suppressed |
| Fluticasone Propionate | Fluticasone Propionate | 36 | 17 |
| Ropinirole Hcl | Ropinirole Hcl | 36 | suppressed |
| Citalopram Hbr | Citalopram Hydrobromide | 35 | suppressed |
| Diclofenac Sodium | Diclofenac Sodium | 35 | 17 |
| Montelukast Sodium | Montelukast Sodium | 35 | suppressed |
| Bupropion Xl | Bupropion Hcl | 33 | suppressed |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 33 | 17 |
| Farxiga | Dapagliflozin Propanediol | 32 | suppressed |
| Linzess | Linaclotide | 32 | suppressed |
| Basaglar Kwikpen U-100 | Insulin Glargine,hum.Rec.Anlog | 29 | suppressed |
| Nitrofurantoin Mono-Macro | Nitrofurantoin Monohyd/M-Cryst | 29 | 20 |
| Cephalexin | Cephalexin | 28 | 17 |
| Propranolol Hcl | Propranolol Hcl | 28 | suppressed |
| Risperidone | Risperidone | 28 | suppressed |
| Calcium Acetate | Calcium Acetate | 27 | suppressed |
| Mesalamine Dr | Mesalamine | 27 | suppressed |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 26 | suppressed |
| Nystatin | Nystatin | 26 | 14 |
| Humalog Kwikpen U-100 | Insulin Lispro | 25 | suppressed |
| Olanzapine | Olanzapine | 25 | suppressed |
| Prednisone | Prednisone | 25 | 12 |
| Tradjenta | Linagliptin | 24 | suppressed |
| Trintellix | Vortioxetine Hydrobromide | 24 | suppressed |
| Azithromycin | Azithromycin | 23 | 14 |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 23 | suppressed |
| Nuplazid | Pimavanserin Tartrate | 22 | suppressed |
| Timolol Maleate | Timolol Maleate | 22 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 22 | suppressed |
| Budesonide | Budesonide | 21 | suppressed |
| Cefdinir | Cefdinir | 21 | 15 |
| Oxybutynin Chloride | Oxybutynin Chloride | 21 | suppressed |
| Clonidine | Clonidine | 20 | suppressed |
| Dorzolamide Hcl | Dorzolamide Hcl | 20 | suppressed |
| Hydrochlorothiazide | Hydrochlorothiazide | 20 | suppressed |
| Januvia | Sitagliptin Phosphate | 20 | suppressed |
| Lidocaine | Lidocaine | 20 | suppressed |
| Carbidopa-Levodopa-Entacapone | Carbidopa/Levodopa/Entacapone | 19 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 19 | suppressed |
| Travoprost | Travoprost | 19 | suppressed |
| Ozempic | Semaglutide | 18 | suppressed |
| Chlorhexidine Gluconate | Chlorhexidine Gluconate | 17 | suppressed |
| Digoxin | Digoxin | 17 | suppressed |
| Galantamine Hbr | Galantamine Hbr | 17 | suppressed |
| Phenytoin Sodium Extended | Phenytoin Sodium Extended | 17 | suppressed |
| Rivastigmine | Rivastigmine Tartrate | 17 | suppressed |
| Simbrinza | Brinzolamide/Brimonidine Tart | 17 | suppressed |
| Alendronate Sodium | Alendronate Sodium | 16 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 16 | 12 |
| Benztropine Mesylate | Benztropine Mesylate | 16 | suppressed |
| Combigan | Brimonidine Tartrate/Timolol | 16 | suppressed |
| Fluconazole | Fluconazole | 16 | 12 |
| Nitrofurantoin | Nitrofurantoin Macrocrystal | 16 | suppressed |
| Prednisolone Acetate | Prednisolone Acetate | 16 | suppressed |
| Atenolol | Atenolol | 15 | suppressed |
| Cilostazol | Cilostazol | 15 | suppressed |
| Clonidine Hcl | Clonidine Hcl | 15 | suppressed |
| Daptomycin | Daptomycin | 15 | suppressed |
| Meloxicam | Meloxicam | 15 | suppressed |
| Amantadine | Amantadine Hcl | 14 | suppressed |
| Carbamazepine | Carbamazepine | 14 | suppressed |
| Divalproex Sodium Er | Divalproex Sodium | 14 | suppressed |
| Doxycycline Hyclate | Doxycycline Hyclate | 14 | suppressed |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 14 | suppressed |
| Jardiance | Empagliflozin | 14 | suppressed |
| Lamotrigine | Lamotrigine | 14 | suppressed |
| Levofloxacin | Levofloxacin | 14 | suppressed |
| Ondansetron Odt | Ondansetron | 14 | suppressed |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 14 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 14 | suppressed |
| Venlafaxine Hcl Er | Venlafaxine Hcl | 14 | suppressed |
| Humalog | Insulin Lispro | 13 | suppressed |
| Lubiprostone | Lubiprostone | 13 | suppressed |
| Meclizine Hcl | Meclizine Hcl | 13 | suppressed |
| Methocarbamol | Methocarbamol | 13 | suppressed |
| Pregabalin | Pregabalin | 13 | suppressed |
| Sucralfate | Sucralfate | 13 | suppressed |
| Verapamil Er | Verapamil Hcl | 13 | suppressed |
| Arnuity Ellipta | Fluticasone Furoate | 12 | suppressed |
| Brilinta | Ticagrelor | 12 | suppressed |
| Brimonidine Tartrate-Timolol | Brimonidine Tartrate/Timolol | 12 | suppressed |
| Prazosin Hcl | Prazosin Hcl | 12 | suppressed |
| Rivastigmine | Rivastigmine | 12 | suppressed |
| Valproic Acid | Valproic Acid | 12 | suppressed |
| Aripiprazole | Aripiprazole | 11 | suppressed |
| Clozapine | Clozapine | 11 | suppressed |
| Diltiazem 24hr Er | Diltiazem Hcl | 11 | suppressed |
| Ertapenem | Ertapenem Sodium | 11 | suppressed |
| Famciclovir | Famciclovir | 11 | suppressed |
| Glucagon Emergency Kit | Glucagon | 11 | suppressed |
| Insulin Lispro Kwikpen U-100 | Insulin Lispro | 11 | suppressed |
| Levemir Flexpen | Insulin Detemir | 11 | suppressed |
| Novolog Flexpen | Insulin Aspart | 11 | suppressed |
| Nyamyc | Nystatin | 11 | suppressed |
Timeline
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $152.84 · 4 records | ACADIA Pharmaceuticals Inc | INGREZZA, NUPLAZID, REXULTI | 1 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error