Healthcare provider profile · identity verified

Isaac Mezo, M.D.

Allopathic & Osteopathic Physicians|Psychiatry & Neurology|Neurology · CHANNAHON, IL · NPI 1346415908

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Isaac Mezo, M.D. received $33,780.77 in general payments during 2025 across 176 reported records.

Axsome Therapeutics, Inc. accounted for 65.9% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 44 associated products.

A separate comparison found the same explicitly named product in public Medicare Part D data: Nurtec Odt, Qulipta, Ubrelvy.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported QULIPTA as an associated drug or biological on 298617 records involving 58957 distinct recipient NPIs. Public Medicare Part D data also shows 70 claims for Qulipta by this doctor in 2024.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported UBRELVY as an associated drug or biological on 299803 records involving 61203 distinct recipient NPIs. Public Medicare Part D data also shows 33 claims for Ubrelvy by this doctor in 2024.

MDD US Operations, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Gocovri as an associated drug or biological on 3202 records involving 1029 distinct recipient NPIs. Public Medicare Part D data also shows 24 claims for Gocovri by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported NURTEC ODT as an associated drug or biological on 217574 records involving 54025 distinct recipient NPIs. Public Medicare Part D data also shows 36 claims for Nurtec Odt by this doctor in 2024.

UCB, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Briviact as an associated drug or biological on 13595 records involving 4444 distinct recipient NPIs. Public Medicare Part D data also shows 12 claims for Briviact by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$33,780.77

176 reported records · 36 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
Axsome Therapeutics, Inc. Unresolved — no canonical attribution shown $22,258.6065.9%322025
Eisai Inc. Unresolved — no canonical attribution shown $9,165.6727.1%172025
ABBVIE INC. Unresolved — no canonical attribution shown $525.771.6%352025
Teva Pharmaceuticals USA, Inc. Unresolved — no canonical attribution shown $241.860.7%132025
EMD Serono, Inc. Unresolved — no canonical attribution shown $235.510.7%72025
Novartis Pharmaceuticals Corporation Unresolved — no canonical attribution shown $153.830.5%142025
Merz Pharmaceuticals, LLC Unresolved — no canonical attribution shown $81.290.2%42025
Vanda Pharmaceuticals Inc. Unresolved — no canonical attribution shown $70.860.2%42025
MDD US Operations, LLC Unresolved — no canonical attribution shown $65.540.2%32025
ANI Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $63.400.2%32025
Cala Health, Inc. Unresolved — no canonical attribution shown $58.400.2%22025
SK Life Science, Inc. SK Life Science, Inc.
exact · evidence 2025-04-03
$55.180.2%22025
Tanabe Pharma America, Inc. Unresolved — no canonical attribution shown $54.980.2%32025
ACADIA Pharmaceuticals Inc Unresolved — no canonical attribution shown $52.440.2%32025
Mallinckrodt Hospital Products Inc. Unresolved — no canonical attribution shown $51.160.1%22025
CATALYST PHARMACEUTICALS, INC. Unresolved — no canonical attribution shown $49.940.1%32025
GENZYME CORPORATION Unresolved — no canonical attribution shown $44.300.1%12025
Amneal Pharmaceuticals LLC Unresolved — no canonical attribution shown $39.210.1%22025
JAZZ PHARMACEUTICALS INC. Unresolved — no canonical attribution shown $37.700.1%12025
PFIZER INC. Unresolved — no canonical attribution shown $37.580.1%22025
Biogen, Inc. Unresolved — no canonical attribution shown $36.970.1%22025
Sequel Med Tech, LLC Unresolved — no canonical attribution shown $36.720.1%22025
Genentech USA, Inc. Unresolved — no canonical attribution shown $36.330.1%22025
Tonix Medicines, Inc. Unresolved — no canonical attribution shown $36.140.1%22025
TG Therapeutics, Inc. Unresolved — no canonical attribution shown $34.280.1%12025
SpringWorks Therapeutics, Inc. Unresolved — no canonical attribution shown $33.030.1%22025
Neurocrine BioSciences, Inc. Unresolved — no canonical attribution shown $32.020.1%22025
ARGENX US, INC. Unresolved — no canonical attribution shown $28.690.1%22025
Insulet Corporation Unresolved — no canonical attribution shown $28.110.1%12025
Otsuka Pharmaceutical Development & Commercialization, Inc. Unresolved — no canonical attribution shown $24.090.1%12025
Cycle Pharmaceuticals Inc Unresolved — no canonical attribution shown $22.540.1%12025
Alexion Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $21.190.1%12025
Xeris Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $17.600.1%12025
Impel Pharmaceuticals LLC Unresolved — no canonical attribution shown $17.260.1%12025
Novo Nordisk Inc Unresolved — no canonical attribution shown $16.950.1%12025
UCB, Inc. Unresolved — no canonical attribution shown $15.630.1%12025

What were the payments for?

Payment categories

CategoryAmountRecords
Honoraria$20,900.006
Compensation for serving as faculty or as a speaker for a medical education program$7,422.5010
Food and Beverage$3,282.01152
Travel and Lodging$1,040.775
Consulting Fee$1,000.001
Education$135.492

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
Symbravo
Normalized: symbravo
Drug Axsome Therapeutics, Inc. $22,234.40 29 2025
Source payment records
Leqembi
Normalized: leqembi
Drug Eisai Inc. $9,165.67 17 2025
Source payment records
QULIPTA
Normalized: qulipta
Drug ABBVIE INC. $421.59 28 2025
Source payment records
UBRELVY
Normalized: ubrelvy
Drug ABBVIE INC. $412.38 28 2025
Source payment records
AUSTEDO XR
Normalized: austedo xr
Drug Teva Pharmaceuticals USA, Inc. $154.37 12 2025
Source payment records
KESIMPTA
Normalized: kesimpta
Drug Novartis Pharmaceuticals Corporation $153.83 14 2025
Source payment records
BOTOX
Normalized: botox
Biological ABBVIE INC. $85.88 5 2025
Source payment records
PONVORY
Normalized: ponvory
Drug Vanda Pharmaceuticals Inc. $70.86 4 2025
Source payment records
PURIFIED CORTROPHIN GEL
Normalized: purified cortrophin gel
Drug ANI Pharmaceuticals, Inc. $63.40 3 2025
Source payment records
INBRIJA
Normalized: inbrija
Drug Merz Pharmaceuticals, LLC $62.32 3 2025
Source payment records
Cala kIQ
Normalized: cala kiq
Device Cala Health, Inc. $58.40 2 2025
Source payment records
Xeomin
Normalized: xeomin
Biological Merz Pharmaceuticals, LLC $55.42 3 2025
Source payment records
Radicava
Normalized: radicava
Drug Tanabe Pharma America, Inc. $54.98 3 2025
Source payment records
ACTHAR
Normalized: acthar
Biological Mallinckrodt Hospital Products Inc. $51.16 2 2025
Source payment records
FYCOMPA
Normalized: fycompa
Drug CATALYST PHARMACEUTICALS, INC. $49.94 3 2025
Source payment records
XYWAV
Normalized: xywav
Drug JAZZ PHARMACEUTICALS INC. $37.70 1 2025
Source payment records
NURTEC ODT
Normalized: nurtec odt
Drug PFIZER INC. $37.58 2 2025
Source payment records
ZAVZPRET
Normalized: zavzpret
Drug PFIZER INC. $37.58 2 2025
Source payment records
TYSABRI
Normalized: tysabri
Biological Biogen, Inc. $36.97 2 2025
Source payment records
VUMERITY
Normalized: vumerity
Drug Biogen, Inc. $36.97 2 2025
Source payment records
TWIIST
Normalized: twiist
Device Sequel Med Tech, LLC $36.72 2 2025
Source payment records
Ocrevus Zunovo
Normalized: ocrevus zunovo
Biological Genentech USA, Inc. $36.33 2 2025
Source payment records
ZEMBRACE SYMTOUCH
Normalized: zembrace symtouch
Drug Tonix Medicines, Inc. $36.14 2 2025
Source payment records
NUPLAZID
Normalized: nuplazid
Drug ACADIA Pharmaceuticals Inc $35.17 2 2025
Source payment records
BRIUMVI
Normalized: briumvi
Drug TG Therapeutics, Inc. $34.28 1 2025
Source payment records
GOMEKLI
Normalized: gomekli
Drug SpringWorks Therapeutics, Inc. $33.03 2 2025
Source payment records
INGREZZA
Normalized: ingrezza
Drug Neurocrine BioSciences, Inc. $32.02 2 2025
Source payment records
VYVGART
Normalized: vyvgart
Drug ARGENX US, INC. $28.69 2 2025
Source payment records
VYVGART HYTRULO
Normalized: vyvgart hytrulo
Drug ARGENX US, INC. $28.69 2 2025
Source payment records
Omnipod
Normalized: omnipod
Device Insulet Corporation $28.11 1 2025
Source payment records
Sunosi
Normalized: sunosi
Drug Axsome Therapeutics, Inc. $24.20 3 2025
Source payment records
REXULTI
Normalized: rexulti
Drug Otsuka Pharmaceutical Development & Commercialization, Inc. $24.09 1 2025
Source payment records
  • 2025-03-25 · Otsuka Pharmaceutical Development & Commercialization, Inc. · $24.09 · Open Payments source
Qelbree
Normalized: qelbree
Drug MDD US Operations, LLC $23.40 1 2025
Source payment records
BREKIYA
Normalized: brekiya
Drug Amneal Pharmaceuticals LLC $22.97 1 2025
Source payment records
Bafiertam
Normalized: bafiertam
Drug Cycle Pharmaceuticals Inc $22.54 1 2025
Source payment records
Tascenso ODT
Normalized: tascenso odt
Drug Cycle Pharmaceuticals Inc $22.54 1 2025
Source payment records
ULTOMIRIS
Normalized: ultomiris
Biological Alexion Pharmaceuticals, Inc. $21.19 1 2025
Source payment records
KEVEYIS
Normalized: keveyis
Drug Xeris Pharmaceuticals, Inc. $17.60 1 2025
Source payment records
DAYBUE
Normalized: daybue
Drug ACADIA Pharmaceuticals Inc $17.27 1 2025
Source payment records
TRUDHESA
Normalized: trudhesa
Drug Impel Pharmaceuticals LLC $17.26 1 2025
Source payment records
Wegovy
Normalized: wegovy
Drug Novo Nordisk Inc $16.95 1 2025
Source payment records
CREXONT
Normalized: crexont
Drug Amneal Pharmaceuticals LLC $16.24 1 2025
Source payment records
AMPYRA
Normalized: ampyra
Drug Merz Pharmaceuticals, LLC $15.82 1 2025
Source payment records
Zilbrysq
Normalized: zilbrysq
Drug UCB, Inc. $15.63 1 2025
Source payment records

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
NURTEC ODT
nurtec odt
2025 Nurtec Odt 2024 36
Beneficiary count suppressed
exact normalized Medicare Part D
QULIPTA
qulipta
2025 Qulipta 2024 70 exact normalized Medicare Part D
UBRELVY
ubrelvy
2025 Ubrelvy 2024 33
Beneficiary count suppressed
exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 QULIPTA
open payments reported associated product
CMS Open Payments — General Payments
298617 supporting records · 58957 recipient NPIs · example record 1201352530
Qulipta · 2024
Exact normalized brand match · 1 Part D row
70 14
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 UBRELVY
open payments reported associated product
CMS Open Payments — General Payments
299803 supporting records · 61203 recipient NPIs · example record 1201352530
Ubrelvy · 2024
Exact normalized brand match · 1 Part D row
33 suppressed by CMS
MDD US Operations, LLC
Exact reporting entity; no affiliate inference
2025 Gocovri
open payments reported associated product
CMS Open Payments — General Payments
3202 supporting records · 1029 recipient NPIs · example record 1241843637
Gocovri · 2024
Exact normalized brand match · 1 Part D row
24 suppressed by CMS
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 NURTEC ODT
open payments reported associated product
CMS Open Payments — General Payments
217574 supporting records · 54025 recipient NPIs · example record 1228794063
Nurtec Odt · 2024
Exact normalized brand match · 1 Part D row
36 suppressed by CMS
UCB, Inc.
Exact reporting entity; no affiliate inference
2025 Briviact
open payments reported associated product
CMS Open Payments — General Payments
13595 supporting records · 4444 recipient NPIs · example record 1224348489
Briviact · 2024
Exact normalized brand match · 1 Part D row
12 suppressed by CMS

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Carbidopa-LevodopaCarbidopa/Levodopa16550
Memantine HclMemantine Hcl16139
LevetiracetamLevetiracetam15631
GabapentinGabapentin15355
Donepezil HclDonepezil Hcl11636
PrimidonePrimidone10525
PregabalinPregabalin7024
QuliptaAtogepant7014
Pramipexole DihydrochloridePramipexole Di-Hcl6513
ClonazepamClonazepam6017
Divalproex Sodium ErDivalproex Sodium54suppressed
Amitriptyline HclAmitriptyline Hcl5317
Divalproex SodiumDivalproex Sodium4812
TopiramateTopiramate46suppressed
Duloxetine HclDuloxetine Hcl4412
CarbamazepineCarbamazepine42suppressed
Quetiapine FumarateQuetiapine Fumarate37suppressed
Butalbital-Acetaminophen-CaffeButalb/Acetaminophen/Caffeine3614
Nurtec OdtRimegepant Sulfate36suppressed
Ropinirole HclRopinirole Hcl34suppressed
UbrelvyUbrogepant33suppressed
Tizanidine HclTizanidine Hcl30suppressed
Ondansetron OdtOndansetron28suppressed
LacosamideLacosamide26suppressed
LamotrigineLamotrigine26suppressed
GocovriAmantadine Hcl24suppressed
OxcarbazepineOxcarbazepine24suppressed
PrednisonePrednisone2412
AptiomEslicarbazepine Acetate22suppressed
Carbamazepine ErCarbamazepine21suppressed
Cyclobenzaprine HclCyclobenzaprine Hcl20suppressed
Atorvastatin CalciumAtorvastatin Calcium18suppressed
Phenytoin Sodium ExtendedPhenytoin Sodium Extended18suppressed
Escitalopram OxalateEscitalopram Oxalate16suppressed
PhenobarbitalPhenobarbital16suppressed
Pyridostigmine BromidePyridostigmine Bromide16suppressed
Sumatriptan SuccinateSumatriptan Succinate16suppressed
BaclofenBaclofen15suppressed
GammakedImmune Globul G/Gly/Iga Avg 4615suppressed
Ondansetron HclOndansetron Hcl15suppressed
RizatriptanRizatriptan Benzoate15suppressed
AlprazolamAlprazolam14suppressed
Valproic AcidValproic Acid (As Sodium Salt)14suppressed
Ajovy AutoinjectorFremanezumab-Vfrm13suppressed
DroxidopaDroxidopa13suppressed
Propranolol HclPropranolol Hcl13suppressed
Sodium Chloride0.9 % Sodium Chloride13suppressed
Tramadol HclTramadol Hcl13suppressed
Amlodipine BesylateAmlodipine Besylate12suppressed
AripiprazoleAripiprazole12suppressed
BriviactBrivaracetam12suppressed
ClopidogrelClopidogrel Bisulfate12suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $33,780.77 · 176 records Axsome Therapeutics, Inc. ACTHAR, AMPYRA, AUSTEDO XR, BOTOX, BREKIYA, BRIUMVI, Bafiertam, CREXONT, Cala kIQ, DAYBUE, FYCOMPA, GOMEKLI, INBRIJA, INGREZZA, KESIMPTA, KEVEYIS, Leqembi, NUPLAZID, NURTEC ODT, Ocrevus Zunovo, Omnipod, PONVORY, PURIFIED CORTROPHIN GEL, QULIPTA, Qelbree, REXULTI, Radicava, Sunosi, Symbravo, TRUDHESA, TWIIST, TYSABRI, Tascenso ODT, UBRELVY, ULTOMIRIS, VUMERITY, VYVGART, VYVGART HYTRULO, Wegovy, XYWAV, Xeomin, ZAVZPRET, ZEMBRACE SYMTOUCH, Zilbrysq 5
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error