Healthcare provider profile · identity verified

Adrian Antonio Santamaria, MD

Allopathic & Osteopathic Physicians|Psychiatry & Neurology|Neurology · TOMBALL, TX · NPI 1346444932

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Adrian Antonio Santamaria, MD received $25,267.55 in general payments during 2025 across 173 reported records.

Inspire Medical Systems, Inc. accounted for 33.7% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 39 associated products.

A separate comparison found the same explicitly named product in public Medicare Part D data: Gamunex-C, Lumryz, Nurtec Odt, Wakix, Xywav.

Amneal Pharmaceuticals LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported RYTARY as an associated drug or biological on 200 records involving 121 distinct recipient NPIs. Public Medicare Part D data also shows 26 claims for Rytary by this doctor in 2024.

Avadel CNS Pharmaceuticals, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LUMRYZ as an associated drug or biological on 11767 records involving 3739 distinct recipient NPIs. Public Medicare Part D data also shows 21 claims for Lumryz by this doctor in 2024.

Grifols USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Gamunex-C as an associated drug or biological on 3977 records involving 2134 distinct recipient NPIs. Public Medicare Part D data also shows 26 claims for Gamunex-C by this doctor in 2024.

HARMONY BIOSCIENCES LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported WAKIX as an associated drug or biological on 20652 records involving 6156 distinct recipient NPIs. Public Medicare Part D data also shows 15 claims for Wakix by this doctor in 2024.

JAZZ PHARMACEUTICALS INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported XYWAV as an associated drug or biological on 19511 records involving 5343 distinct recipient NPIs. Public Medicare Part D data also shows 70 claims for Xywav by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported NURTEC ODT as an associated drug or biological on 217574 records involving 54025 distinct recipient NPIs. Public Medicare Part D data also shows 28 claims for Nurtec Odt by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$25,267.55

173 reported records · 34 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
Inspire Medical Systems, Inc. Unresolved — no canonical attribution shown $8,519.0833.7%552025
Avadel CNS Pharmaceuticals, LLC Unresolved — no canonical attribution shown $8,055.6031.9%162025
JAZZ PHARMACEUTICALS INC. Unresolved — no canonical attribution shown $6,748.3426.7%122025
HARMONY BIOSCIENCES LLC Unresolved — no canonical attribution shown $329.461.3%112025
ABBVIE INC. Unresolved — no canonical attribution shown $178.100.7%132025
Eisai Inc. Unresolved — no canonical attribution shown $136.320.5%62025
SK Life Science, Inc. SK Life Science, Inc.
exact · evidence 2025-04-03
$135.610.5%42025
Abbott Laboratories Unresolved — no canonical attribution shown $114.250.5%52025
Genentech USA, Inc. Unresolved — no canonical attribution shown $102.350.4%62025
Axsome Therapeutics, Inc. Unresolved — no canonical attribution shown $86.770.3%32025
PFIZER INC. Unresolved — no canonical attribution shown $81.490.3%32025
Teva Pharmaceuticals USA, Inc. Unresolved — no canonical attribution shown $68.000.3%32025
ACADIA Pharmaceuticals Inc Unresolved — no canonical attribution shown $60.050.2%32025
UCB, Inc. Unresolved — no canonical attribution shown $59.600.2%22025
Aucta Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $55.940.2%72025
ARGENX US, INC. Unresolved — no canonical attribution shown $47.170.2%22025
Neurocrine BioSciences, Inc. Unresolved — no canonical attribution shown $46.400.2%22025
Otsuka America Pharmaceutical, Inc. Unresolved — no canonical attribution shown $41.480.2%22025
Novartis Pharmaceuticals Corporation Unresolved — no canonical attribution shown $38.820.1%22025
TG Therapeutics, Inc. Unresolved — no canonical attribution shown $38.070.1%12025
Impel Pharmaceuticals LLC Unresolved — no canonical attribution shown $30.940.1%22025
Takeda Pharmaceuticals U.S.A., Inc. Unresolved — no canonical attribution shown $30.320.1%12025
Amgen Inc. Unresolved — no canonical attribution shown $27.100.1%12025
Grifols USA, LLC Unresolved — no canonical attribution shown $25.790.1%12025
Life Molecular Imaging Ltd Unresolved — no canonical attribution shown $24.810.1%12025
3B Medical, Inc. Unresolved — no canonical attribution shown $24.790.1%12025
Alexion Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $24.590.1%12025
Celgene Corporation Unresolved — no canonical attribution shown $23.100.1%12025
Lilly USA, LLC Unresolved — no canonical attribution shown $22.400.1%12025
Philips North America LLC Unresolved — no canonical attribution shown $21.940.1%12025
Xeris Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $20.270.1%12025
Lundbeck LLC Unresolved — no canonical attribution shown $18.780.1%12025
ZOLL Respicardia, Inc. Unresolved — no canonical attribution shown $16.090.1%12025
Amneal Pharmaceuticals LLC Unresolved — no canonical attribution shown $13.730.1%12025

What were the payments for?

Payment categories

CategoryAmountRecords
Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program$9,275.005
Consulting Fee$9,095.003
Food and Beverage$3,606.67145
Honoraria$2,000.001
Travel and Lodging$1,184.9317
Education$105.952

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
INSPIRE
Normalized: inspire
Device Inspire Medical Systems, Inc. $8,519.08 55 2025
Source payment records
LUMRYZ
Normalized: lumryz
Drug Avadel CNS Pharmaceuticals, LLC $8,055.60 16 2025
Source payment records
XYWAV
Normalized: xywav
Drug JAZZ PHARMACEUTICALS INC. $6,748.34 12 2025
Source payment records
WAKIX
Normalized: wakix
Drug HARMONY BIOSCIENCES LLC $329.46 11 2025
Source payment records
QULIPTA
Normalized: qulipta
Drug ABBVIE INC. $178.10 13 2025
Source payment records
Leqembi
Normalized: leqembi
Drug Eisai Inc. $136.32 6 2025
Source payment records
Ocrevus Zunovo
Normalized: ocrevus zunovo
Biological Genentech USA, Inc. $102.35 6 2025
Source payment records
UBRELVY
Normalized: ubrelvy
Drug ABBVIE INC. $91.05 7 2025
Source payment records
Sunosi
Normalized: sunosi
Drug Axsome Therapeutics, Inc. $86.77 3 2025
Source payment records
NURTEC ODT
Normalized: nurtec odt
Drug PFIZER INC. $81.49 3 2025
Source payment records
ZAVZPRET
Normalized: zavzpret
Drug PFIZER INC. $81.49 3 2025
Source payment records
INFINITY
Normalized: infinity
Device Abbott Laboratories $68.39 3 2025
Source payment records
AUSTEDO XR
Normalized: austedo xr
Drug Teva Pharmaceuticals USA, Inc. $68.00 3 2025
Source payment records
NUPLAZID
Normalized: nuplazid
Drug ACADIA Pharmaceuticals Inc $60.05 3 2025
Source payment records
Motpoly XR
Normalized: motpoly xr
Drug Aucta Pharmaceuticals, Inc. $55.94 7 2025
Source payment records
VYVGART HYTRULO
Normalized: vyvgart hytrulo
Drug ARGENX US, INC. $47.17 2 2025
Source payment records
INGREZZA
Normalized: ingrezza
Drug Neurocrine BioSciences, Inc. $46.40 2 2025
Source payment records
REXULTI
Normalized: rexulti
Drug Otsuka America Pharmaceutical, Inc. $41.48 2 2025
Source payment records
KESIMPTA
Normalized: kesimpta
Drug Novartis Pharmaceuticals Corporation $38.82 2 2025
Source payment records
BRIUMVI
Normalized: briumvi
Drug TG Therapeutics, Inc. $38.07 1 2025
Source payment records
Rystiggo
Normalized: rystiggo
Drug UCB, Inc. $31.85 1 2025
Source payment records
TRUDHESA
Normalized: trudhesa
Drug Impel Pharmaceuticals LLC $30.94 2 2025
Source payment records
HYQVIA
Normalized: hyqvia
Biological Takeda Pharmaceuticals U.S.A., Inc. $30.32 1 2025
Source payment records
Fintepla
Normalized: fintepla
Drug UCB, Inc. $27.75 1 2025
Source payment records
UPLIZNA
Normalized: uplizna
Biological Amgen Inc. $27.10 1 2025
Source payment records
Gamunex-C
Normalized: gamunex c
Biological Grifols USA, LLC $25.79 1 2025
Source payment records
NEURACEQ
Normalized: neuraceq
Drug Life Molecular Imaging Ltd $24.81 1 2025
Source payment records
LUNA
Normalized: luna
Device 3B Medical, Inc. $24.79 1 2025
Source payment records
ULTOMIRIS
Normalized: ultomiris
Biological Alexion Pharmaceuticals, Inc. $24.59 1 2025
Source payment records
PROCLAIM
Normalized: proclaim
Device Abbott Laboratories $23.36 1 2025
Source payment records
ZEPOSIA
Normalized: zeposia
Drug Celgene Corporation $23.10 1 2025
Source payment records
ETERNA
Normalized: eterna
Device Abbott Laboratories $22.50 1 2025
Source payment records
AMYVID
Normalized: amyvid
Drug Lilly USA, LLC $22.40 1 2025
Source payment records
KISUNLA
Normalized: kisunla
Drug Lilly USA, LLC $22.40 1 2025
Source payment records
Home PI Undivided
Normalized: home pi undivided
Device Philips North America LLC $21.94 1 2025
Source payment records
KEVEYIS
Normalized: keveyis
Drug Xeris Pharmaceuticals, Inc. $20.27 1 2025
Source payment records
VYEPTI
Normalized: vyepti
Biological Lundbeck LLC $18.78 1 2025
Source payment records
remede System
Normalized: remede system
Device ZOLL Respicardia, Inc. $16.09 1 2025
Source payment records
CREXONT
Normalized: crexont
Drug Amneal Pharmaceuticals LLC $13.73 1 2025
Source payment records

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
Gamunex-C
gamunex c
2025 Gamunex-C 2024 26
Beneficiary count suppressed
exact normalized Medicare Part D
LUMRYZ
lumryz
2025 Lumryz 2024 21
Beneficiary count suppressed
exact normalized Medicare Part D
NURTEC ODT
nurtec odt
2025 Nurtec Odt 2024 28
Beneficiary count suppressed
exact normalized Medicare Part D
WAKIX
wakix
2025 Wakix 2024 15
Beneficiary count suppressed
exact normalized Medicare Part D
XYWAV
xywav
2025 Xywav 2024 70
Beneficiary count suppressed
exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
Amneal Pharmaceuticals LLC
Exact reporting entity; no affiliate inference
2025 RYTARY
open payments reported associated product
CMS Open Payments — General Payments
200 supporting records · 121 recipient NPIs · example record 1220526035
Rytary · 2024
Exact normalized brand match · 1 Part D row
26 suppressed by CMS
Avadel CNS Pharmaceuticals, LLC
Exact reporting entity; no affiliate inference
2025 LUMRYZ
open payments reported associated product
CMS Open Payments — General Payments
11767 supporting records · 3739 recipient NPIs · example record 1208530440
Lumryz · 2024
Exact normalized brand match · 1 Part D row
21 suppressed by CMS
Grifols USA, LLC
Exact reporting entity; no affiliate inference
2025 Gamunex-C
open payments reported associated product
CMS Open Payments — General Payments
3977 supporting records · 2134 recipient NPIs · example record 1249529381
Gamunex-C · 2024
Exact normalized brand match · 1 Part D row
26 suppressed by CMS
HARMONY BIOSCIENCES LLC
Exact reporting entity; no affiliate inference
2025 WAKIX
open payments reported associated product
CMS Open Payments — General Payments
20652 supporting records · 6156 recipient NPIs · example record 1222387076
Wakix · 2024
Exact normalized brand match · 1 Part D row
15 suppressed by CMS
JAZZ PHARMACEUTICALS INC.
Exact reporting entity; no affiliate inference
2025 XYWAV
open payments reported associated product
CMS Open Payments — General Payments
19511 supporting records · 5343 recipient NPIs · example record 1234297700
Xywav · 2024
Exact normalized brand match · 1 Part D row
70 suppressed by CMS
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 NURTEC ODT
open payments reported associated product
CMS Open Payments — General Payments
217574 supporting records · 54025 recipient NPIs · example record 1228794063
Nurtec Odt · 2024
Exact normalized brand match · 1 Part D row
28 suppressed by CMS

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Pramipexole DihydrochloridePramipexole Di-Hcl24675
Memantine HclMemantine Hcl21661
GabapentinGabapentin18168
LevetiracetamLevetiracetam15346
Carbidopa-LevodopaCarbidopa/Levodopa15046
Sertraline HclSertraline Hcl12734
ClonazepamClonazepam11025
Donepezil HclDonepezil Hcl8133
LacosamideLacosamide7311
XywavSodium,calcium,mag,pot Oxybate70suppressed
Amitriptyline HclAmitriptyline Hcl6623
Zolpidem TartrateZolpidem Tartrate6621
Propranolol HclPropranolol Hcl5618
RivastigmineRivastigmine Tartrate4816
LamotrigineLamotrigine4013
TopiramateTopiramate38suppressed
PregabalinPregabalin3711
Cyclobenzaprine HclCyclobenzaprine Hcl36suppressed
EszopicloneEszopiclone3512
Quetiapine FumarateQuetiapine Fumarate35suppressed
Carbamazepine ErCarbamazepine34suppressed
ArmodafinilArmodafinil33suppressed
ZonisamideZonisamide33suppressed
RizatriptanRizatriptan Benzoate32suppressed
Sumatriptan SuccinateSumatriptan Succinate3112
Sodium OxybateSodium Oxybate30suppressed
Divalproex SodiumDivalproex Sodium29suppressed
Nurtec OdtRimegepant Sulfate28suppressed
Dextroamphetamine-AmphetamineDextroamphetamine/Amphetamine27suppressed
Gamunex-CImmune Globul G/Gly/Iga Avg 4626suppressed
RytaryCarbidopa/Levodopa26suppressed
Escitalopram OxalateEscitalopram Oxalate25suppressed
Trazodone HclTrazodone Hcl25suppressed
Butalbital-Acetaminophen-CaffeButalb/Acetaminophen/Caffeine24suppressed
PhenobarbitalPhenobarbital24suppressed
PrimidonePrimidone23suppressed
GammakedImmune Globul G/Gly/Iga Avg 4622suppressed
LumryzSodium Oxybate21suppressed
Zolpidem Tartrate ErZolpidem Tartrate21suppressed
Fluoxetine HclFluoxetine Hcl20suppressed
TemazepamTemazepam20suppressed
Carbidopa-Levodopa ErCarbidopa/Levodopa19suppressed
ModafinilModafinil19suppressed
Aimovig AutoinjectorErenumab-Aooe18suppressed
Paroxetine HclParoxetine Hcl18suppressed
Meclizine HclMeclizine Hcl17suppressed
NeuproRotigotine16suppressed
OxcarbazepineOxcarbazepine16suppressed
WakixPitolisant Hcl15suppressed
CopaxoneGlatiramer Acetate14suppressed
AptiomEslicarbazepine Acetate13suppressed
Divalproex Sodium ErDivalproex Sodium13suppressed
FycompaPerampanel13suppressed
AmantadineAmantadine Hcl12suppressed
Asa-Butalb-Caffeine-CodeineCodeine/Butalbital/Asa/Caffein12suppressed
Eletriptan HbrEletriptan Hydrobromide12suppressed
Promethazine HclPromethazine Hcl12suppressed
ClobazamClobazam11suppressed
Dextroamphetamine SulfateDextroamphetamine Sulfate11suppressed
FingolimodFingolimod Hcl11suppressed
QuviviqDaridorexant Hcl11suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $25,267.55 · 173 records Inspire Medical Systems, Inc. AMYVID, AUSTEDO XR, BRIUMVI, CREXONT, ETERNA, Fintepla, Gamunex-C, HYQVIA, Home PI Undivided, INFINITY, INGREZZA, INSPIRE, KESIMPTA, KEVEYIS, KISUNLA, LUMRYZ, LUNA, Leqembi, Motpoly XR, NEURACEQ, NUPLAZID, NURTEC ODT, Ocrevus Zunovo, PROCLAIM, QULIPTA, REXULTI, Rystiggo, Sunosi, TRUDHESA, UBRELVY, ULTOMIRIS, UPLIZNA, VYEPTI, VYVGART HYTRULO, WAKIX, XYWAV, ZAVZPRET, ZEPOSIA, remede System 6
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error