Payment overview · 2025
General Payments
$69,130.45
96 reported records · 11 companies
Healthcare provider profile · identity verified
Michael Yu Sy, M.D.
Allopathic & Osteopathic Physicians|Psychiatry & Neurology|Neurology · IRVINE, CA · NPI 1376835629
Verified facts
What the public records show
CMS Open Payments records show Michael Yu Sy, M.D. received $69,130.45 in general payments during 2025 across 96 reported records.
Alexion Pharmaceuticals, Inc. accounted for 67.6% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 9 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Ultomiris.
Alexion Pharmaceuticals, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SOLIRIS as an associated drug or biological on 303 records involving 233 distinct recipient NPIs. Public Medicare Part D data also shows 58 claims for Soliris by this doctor in 2024.
Alexion Pharmaceuticals, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ULTOMIRIS as an associated drug or biological on 24281 records involving 10608 distinct recipient NPIs. Public Medicare Part D data also shows 12 claims for Ultomiris by this doctor in 2024.
Biogen, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TECFIDERA as an associated drug or biological on 28 records involving 22 distinct recipient NPIs. Public Medicare Part D data also shows 15 claims for Tecfidera by this doctor in 2024.
Genentech USA, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Enspryng as an associated drug or biological on 186 records involving 143 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Enspryng by this doctor in 2024.
Genentech, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Enspryng as an associated drug or biological on 12 records involving 9 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Enspryng by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Alexion Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $46,742.46 | 67.6% | 43 | 2025 |
| Genentech USA, Inc. | Unresolved — no canonical attribution shown | $8,573.70 | 12.4% | 12 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $5,881.88 | 8.5% | 15 | 2025 |
| UCB, Inc. | Unresolved — no canonical attribution shown | $4,400.00 | 6.4% | 1 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $2,843.20 | 4.1% | 7 | 2025 |
| TG Therapeutics, Inc. | Unresolved — no canonical attribution shown | $231.28 | 0.3% | 6 | 2025 |
| Biogen, Inc. | Unresolved — no canonical attribution shown | $150.00 | 0.2% | 1 | 2025 |
| Vanda Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $136.61 | 0.2% | 7 | 2025 |
| Genentech, Inc. | Unresolved — no canonical attribution shown | $97.12 | 0.1% | 1 | 2025 |
| GENZYME CORPORATION | Unresolved — no canonical attribution shown | $41.95 | 0.1% | 2 | 2025 |
| Celgene Corporation | Unresolved — no canonical attribution shown | $32.25 | 0.1% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program | $39,760.00 | 9 |
| Consulting Fee | $21,680.00 | 7 |
| Travel and Lodging | $5,134.37 | 26 |
| Food and Beverage | $2,495.58 | 53 |
| Education | $60.50 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| ULTOMIRIS Normalized: ultomiris |
Biological | Alexion Pharmaceuticals, Inc. | $42,323.56 | 39 | 2025 |
Source payment records
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| UPLIZNA Normalized: uplizna |
Biological | Amgen Inc. | $5,881.88 | 15 | 2025 |
Source payment records
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| KESIMPTA Normalized: kesimpta |
Drug | Novartis Pharmaceuticals Corporation | $2,843.20 | 7 | 2025 |
Source payment records
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| BRIUMVI Normalized: briumvi |
Drug | TG Therapeutics, Inc. | $231.28 | 6 | 2025 |
Source payment records
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| Ocrevus Zunovo Normalized: ocrevus zunovo |
Biological | Genentech USA, Inc. | $175.22 | 4 | 2025 |
Source payment records
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| TYSABRI Normalized: tysabri |
Biological | Biogen, Inc. | $150.00 | 1 | 2025 |
Source payment records
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| PONVORY Normalized: ponvory |
Drug | Vanda Pharmaceuticals Inc. | $136.61 | 7 | 2025 |
Source payment records
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| Ocrevus Normalized: ocrevus |
Biological | Genentech, Inc. | $97.12 | 1 | 2025 |
Source payment records
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| ZEPOSIA Normalized: zeposia |
Drug | Celgene Corporation | $32.25 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| ULTOMIRIS ultomiris |
2025 | Ultomiris | 2024 | 12 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Alexion Pharmaceuticals, Inc. Exact reporting entity; no affiliate inference |
2025 | SOLIRIS open payments reported associated product |
CMS Open Payments — General Payments 303 supporting records · 233 recipient NPIs · example record 1202913090 |
Soliris · 2024 Exact normalized brand match · 1 Part D row |
58 | suppressed by CMS |
| Alexion Pharmaceuticals, Inc. Exact reporting entity; no affiliate inference |
2025 | ULTOMIRIS open payments reported associated product |
CMS Open Payments — General Payments 24281 supporting records · 10608 recipient NPIs · example record 1202912926 |
Ultomiris · 2024 Exact normalized brand match · 1 Part D row |
12 | suppressed by CMS |
| Biogen, Inc. Exact reporting entity; no affiliate inference |
2025 | TECFIDERA open payments reported associated product |
CMS Open Payments — General Payments 28 supporting records · 22 recipient NPIs · example record 1208304358 |
Tecfidera · 2024 Exact normalized brand match · 1 Part D row |
15 | suppressed by CMS |
| Genentech USA, Inc. Exact reporting entity; no affiliate inference |
2025 | Enspryng open payments reported associated product |
CMS Open Payments — General Payments 186 supporting records · 143 recipient NPIs · example record 1211488510 |
Enspryng · 2024 Exact normalized brand match · 1 Part D row |
43 | suppressed by CMS |
| Genentech, Inc. Exact reporting entity; no affiliate inference |
2025 | Enspryng open payments reported associated product |
CMS Open Payments — General Payments 12 supporting records · 9 recipient NPIs · example record 1211492995 |
Enspryng · 2024 Exact normalized brand match · 1 Part D row |
43 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Baclofen | Baclofen | 103 | 32 |
| Soliris | Eculizumab | 58 | suppressed |
| Kesimpta Pen | Ofatumumab | 56 | suppressed |
| Gabapentin | Gabapentin | 54 | 18 |
| Copaxone | Glatiramer Acetate | 53 | suppressed |
| Glatiramer Acetate | Glatiramer Acetate | 47 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 46 | 13 |
| Enspryng | Satralizumab-Mwge | 43 | suppressed |
| Tamsulosin Hcl | Tamsulosin Hcl | 31 | suppressed |
| Levetiracetam | Levetiracetam | 27 | suppressed |
| Dalfampridine Er | Dalfampridine | 26 | suppressed |
| Sodium Chloride | 0.9 % Sodium Chloride | 24 | suppressed |
| Duloxetine Hcl | Duloxetine Hcl | 20 | suppressed |
| Ibuprofen | Ibuprofen | 20 | suppressed |
| Modafinil | Modafinil | 18 | suppressed |
| Privigen | Immun Glob G(Igg)/Pro/Iga 0-50 | 18 | suppressed |
| Clonazepam | Clonazepam | 17 | suppressed |
| Bupropion Xl | Bupropion Hcl | 16 | suppressed |
| Tecfidera | Dimethyl Fumarate | 15 | suppressed |
| Aimovig Autoinjector | Erenumab-Aooe | 14 | suppressed |
| Dimethyl Fumarate | Dimethyl Fumarate | 13 | suppressed |
| Lacosamide | Lacosamide | 13 | suppressed |
| Teriflunomide | Teriflunomide | 13 | suppressed |
| Methylprednisolone Sodium Succ | Methylprednisolone Sod Succ | 12 | suppressed |
| Ultomiris | Ravulizumab-Cwvz | 12 | suppressed |
| Pregabalin | Pregabalin | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $69,130.45 · 96 records | Alexion Pharmaceuticals, Inc. | BRIUMVI, KESIMPTA, Ocrevus, Ocrevus Zunovo, PONVORY, TYSABRI, ULTOMIRIS, UPLIZNA, ZEPOSIA | 5 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Ultomiris play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Alexion Pharmaceuticals, Inc.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error