Payment overview · 2025
General Payments
$250.51
2 reported records · 2 companies
Healthcare provider profile · identity verified
Luigi Simone, M.D.
Allopathic & Osteopathic Physicians|Family Medicine · ENCINITAS, CA · NPI 1407951338
Verified facts
What the public records show
CMS Open Payments records show Luigi Simone, M.D. received $250.51 in general payments during 2025 across 2 reported records.
Alnylam Pharmaceuticals Inc. accounted for 58.4% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 2 associated products.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Alnylam Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $146.21 | 58.4% | 1 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $104.30 | 41.6% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $250.51 | 2 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| AMVUTTRA Normalized: amvuttra |
Drug | Alnylam Pharmaceuticals Inc. | $146.21 | 1 | 2025 |
Source payment records
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| Kerendia Normalized: kerendia |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $104.30 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
No exact normalized or approved-alias overlap was found in the loaded Part D year. This does not mean the doctor never prescribed the product.
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
No publishable same-company prescribing overlap was found in the loaded Part D year. This does not mean the doctor never prescribed a drug reported elsewhere by a paying company.
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Atorvastatin Calcium | Atorvastatin Calcium | 332 | 113 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 293 | 93 |
| Losartan Potassium | Losartan Potassium | 287 | 85 |
| Amlodipine Besylate | Amlodipine Besylate | 277 | 88 |
| Lisinopril | Lisinopril | 201 | 65 |
| Levothyroxine Sodium | Levothyroxine Sodium | 180 | 61 |
| Pantoprazole Sodium | Pantoprazole Sodium | 155 | 47 |
| Hydrochlorothiazide | Hydrochlorothiazide | 148 | 45 |
| Gabapentin | Gabapentin | 127 | 37 |
| Metoprolol Succinate | Metoprolol Succinate | 114 | 39 |
| Allopurinol | Allopurinol | 109 | 27 |
| Simvastatin | Simvastatin | 108 | 29 |
| Tamsulosin Hcl | Tamsulosin Hcl | 108 | 35 |
| Escitalopram Oxalate | Escitalopram Oxalate | 100 | 33 |
| Metformin Hcl Er | Metformin Hcl | 83 | 28 |
| Metformin Hcl | Metformin Hcl | 79 | 28 |
| Bupropion Xl | Bupropion Hcl | 74 | 24 |
| Valsartan | Valsartan | 74 | 25 |
| Finasteride | Finasteride | 71 | 24 |
| Trazodone Hcl | Trazodone Hcl | 70 | 23 |
| Atenolol | Atenolol | 69 | 17 |
| Alendronate Sodium | Alendronate Sodium | 68 | 23 |
| Sertraline Hcl | Sertraline Hcl | 63 | 16 |
| Synthroid | Levothyroxine Sodium | 58 | 15 |
| Duloxetine Hcl | Duloxetine Hcl | 53 | 21 |
| Eliquis | Apixaban | 50 | 16 |
| Pravastatin Sodium | Pravastatin Sodium | 50 | 11 |
| Famotidine | Famotidine | 48 | 14 |
| Omeprazole | Omeprazole | 47 | 18 |
| Lisinopril-Hydrochlorothiazide | Lisinopril/Hydrochlorothiazide | 46 | 17 |
| Ozempic | Semaglutide | 45 | suppressed |
| Furosemide | Furosemide | 42 | 13 |
| Alprazolam | Alprazolam | 41 | 12 |
| Ezetimibe | Ezetimibe | 40 | 13 |
| Metoprolol Tartrate | Metoprolol Tartrate | 39 | 13 |
| Valsartan-Hydrochlorothiazide | Valsartan/Hydrochlorothiazide | 39 | 11 |
| Carvedilol | Carvedilol | 38 | 12 |
| Fluoxetine Hcl | Fluoxetine Hcl | 35 | 13 |
| Valacyclovir | Valacyclovir Hcl | 34 | 15 |
| Zolpidem Tartrate | Zolpidem Tartrate | 34 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 32 | 11 |
| Acyclovir | Acyclovir | 30 | 12 |
| Terazosin Hcl | Terazosin Hcl | 30 | suppressed |
| Losartan-Hydrochlorothiazide | Losartan/Hydrochlorothiazide | 29 | suppressed |
| Montelukast Sodium | Montelukast Sodium | 29 | suppressed |
| Triamcinolone Acetonide | Triamcinolone Acetonide | 28 | 20 |
| Spironolactone | Spironolactone | 26 | suppressed |
| Fluticasone Propionate | Fluticasone Propionate | 25 | 16 |
| Jardiance | Empagliflozin | 24 | suppressed |
| Venlafaxine Hcl Er | Venlafaxine Hcl | 23 | suppressed |
| Amlodipine Besylate-Benazepril | Amlodipine Besylate/Benazepril | 22 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 22 | 20 |
| Estradiol | Estradiol | 21 | suppressed |
| Prednisone | Prednisone | 21 | 20 |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 20 | suppressed |
| Citalopram Hbr | Citalopram Hydrobromide | 19 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 19 | suppressed |
| Lovastatin | Lovastatin | 19 | suppressed |
| Benazepril Hcl | Benazepril Hcl | 18 | suppressed |
| Triamterene-Hydrochlorothiazid | Triamterene/Hydrochlorothiazid | 18 | suppressed |
| Dutasteride | Dutasteride | 17 | suppressed |
| Azelastine Hcl | Azelastine Hcl | 16 | suppressed |
| Breo Ellipta | Fluticasone/Vilanterol | 16 | suppressed |
| Potassium Chloride | Potassium Chloride | 16 | suppressed |
| Quetiapine Fumarate | Quetiapine Fumarate | 16 | suppressed |
| Testosterone | Testosterone | 16 | suppressed |
| Chlorthalidone | Chlorthalidone | 15 | suppressed |
| Doxycycline Hyclate | Doxycycline Hyclate | 15 | 12 |
| Ketoconazole | Ketoconazole | 15 | suppressed |
| Nifedipine Er | Nifedipine | 15 | suppressed |
| Celecoxib | Celecoxib | 14 | suppressed |
| Mirtazapine | Mirtazapine | 14 | suppressed |
| Clopidogrel | Clopidogrel Bisulfate | 13 | suppressed |
| Symbicort | Budesonide/Formoterol Fumarate | 13 | suppressed |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 12 | suppressed |
| Amitriptyline Hcl | Amitriptyline Hcl | 12 | suppressed |
| Cevimeline Hcl | Cevimeline Hcl | 12 | suppressed |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 12 | suppressed |
| Lidocaine | Lidocaine | 12 | suppressed |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 12 | suppressed |
| Ventolin Hfa | Albuterol Sulfate | 12 | suppressed |
| Benazepril-Hydrochlorothiazide | Benazepril/Hydrochlorothiazide | 11 | suppressed |
| Buspirone Hcl | Buspirone Hcl | 11 | suppressed |
| Donepezil Hcl | Donepezil Hcl | 11 | suppressed |
| Pramipexole Dihydrochloride | Pramipexole Di-Hcl | 11 | suppressed |
| Repatha Sureclick | Evolocumab | 11 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 11 | suppressed |
| Ultra-Fine Mini Pen Needle | Pen Needle, Diabetic | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $250.51 · 2 records | Alnylam Pharmaceuticals Inc. | AMVUTTRA, Kerendia | — | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error