Payment overview · 2025
General Payments
1 reported records · 1 companies
Healthcare provider profile · identity verified
Allopathic & Osteopathic Physicians|Internal Medicine · SAN ANTONIO, TX · NPI 1437169125
Verified facts
CMS Open Payments records show Luis Ysmael Silva, MD received $19.65 in general payments during 2025 across 1 reported records.
Otsuka America Pharmaceutical, Inc. accounted for 100.0% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 1 associated product.
These records do not establish that a payment influenced prescribing or medical care.
Payment overview · 2025
1 reported records · 1 companies
Separate record types
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Otsuka America Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $19.65 | 100.0% | 1 | 2025 |
What were the payments for?
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $19.65 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| REXULTI Normalized: rexulti |
Drug | Otsuka America Pharmaceutical, Inc. | $19.65 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
No exact normalized or approved-alias overlap was found in the loaded Part D year. This does not mean the doctor never prescribed the product.
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
No publishable same-company prescribing overlap was found in the loaded Part D year. This does not mean the doctor never prescribed a drug reported elsewhere by a paying company.
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Atorvastatin Calcium | Atorvastatin Calcium | 564 | 119 |
| Levothyroxine Sodium | Levothyroxine Sodium | 516 | 74 |
| Eliquis | Apixaban | 453 | 62 |
| Gabapentin | Gabapentin | 406 | 78 |
| Furosemide | Furosemide | 359 | 72 |
| Sertraline Hcl | Sertraline Hcl | 295 | 50 |
| Amlodipine Besylate | Amlodipine Besylate | 271 | 63 |
| Donepezil Hcl | Donepezil Hcl | 256 | 43 |
| Potassium Chloride | Potassium Chloride | 234 | 41 |
| Pantoprazole Sodium | Pantoprazole Sodium | 231 | 56 |
| Metoprolol Tartrate | Metoprolol Tartrate | 223 | 64 |
| Memantine Hcl | Memantine Hcl | 203 | 37 |
| Mirtazapine | Mirtazapine | 199 | 44 |
| Tramadol Hcl | Tramadol Hcl | 197 | 41 |
| Metformin Hcl | Metformin Hcl | 195 | 31 |
| Carvedilol | Carvedilol | 188 | 48 |
| Trazodone Hcl | Trazodone Hcl | 188 | 44 |
| Clopidogrel | Clopidogrel Bisulfate | 185 | 38 |
| Omeprazole | Omeprazole | 185 | 41 |
| Lisinopril | Lisinopril | 183 | 41 |
| Losartan Potassium | Losartan Potassium | 166 | 37 |
| Tamsulosin Hcl | Tamsulosin Hcl | 165 | 42 |
| Hydralazine Hcl | Hydralazine Hcl | 156 | 39 |
| Xarelto | Rivaroxaban | 146 | 13 |
| Myrbetriq | Mirabegron | 144 | 17 |
| Escitalopram Oxalate | Escitalopram Oxalate | 112 | 24 |
| Divalproex Sodium | Divalproex Sodium | 109 | 27 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 109 | 22 |
| Acetaminophen-Codeine | Acetaminophen With Codeine | 108 | 26 |
| Buspirone Hcl | Buspirone Hcl | 107 | 28 |
| Duloxetine Hcl | Duloxetine Hcl | 107 | 22 |
| Famotidine | Famotidine | 107 | 27 |
| Metoprolol Succinate | Metoprolol Succinate | 106 | 35 |
| Citalopram Hbr | Citalopram Hydrobromide | 95 | 23 |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 92 | 28 |
| Levetiracetam | Levetiracetam | 91 | 23 |
| Montelukast Sodium | Montelukast Sodium | 89 | 20 |
| Ipratropium-Albuterol | Ipratropium/Albuterol Sulfate | 87 | 45 |
| Nifedipine Er | Nifedipine | 86 | 30 |
| Clonazepam | Clonazepam | 83 | suppressed |
| Quetiapine Fumarate | Quetiapine Fumarate | 79 | 20 |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 78 | 21 |
| Latanoprost | Latanoprost | 76 | 19 |
| Pregabalin | Pregabalin | 76 | 11 |
| Alprazolam | Alprazolam | 74 | 12 |
| Ondansetron Hcl | Ondansetron Hcl | 73 | 47 |
| Pravastatin Sodium | Pravastatin Sodium | 73 | 12 |
| Finasteride | Finasteride | 70 | 11 |
| Allopurinol | Allopurinol | 69 | 15 |
| Tradjenta | Linagliptin | 68 | suppressed |
| Midodrine Hcl | Midodrine Hcl | 67 | 23 |
| Jardiance | Empagliflozin | 61 | suppressed |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 61 | 14 |
| Bumetanide | Bumetanide | 60 | 12 |
| Levofloxacin | Levofloxacin | 58 | 39 |
| Amiodarone Hcl | Amiodarone Hcl | 57 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 56 | 32 |
| Basaglar Kwikpen U-100 | Insulin Glargine,hum.Rec.Anlog | 56 | 14 |
| Lamotrigine | Lamotrigine | 56 | 11 |
| Oxybutynin Chloride | Oxybutynin Chloride | 56 | 11 |
| Humalog Kwikpen U-100 | Insulin Lispro | 52 | 22 |
| Meclizine Hcl | Meclizine Hcl | 52 | suppressed |
| Baclofen | Baclofen | 51 | 14 |
| Fluticasone Propionate | Fluticasone Propionate | 51 | 16 |
| Nitrofurantoin Mono-Macro | Nitrofurantoin Monohyd/M-Cryst | 51 | 33 |
| Simvastatin | Simvastatin | 51 | 14 |
| Farxiga | Dapagliflozin Propanediol | 50 | suppressed |
| Januvia | Sitagliptin Phosphate | 50 | suppressed |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 49 | 11 |
| Fluoxetine Hcl | Fluoxetine Hcl | 48 | 14 |
| Spironolactone | Spironolactone | 48 | 13 |
| Cyclobenzaprine Hcl | Cyclobenzaprine Hcl | 47 | 11 |
| Lactulose | Lactulose | 47 | 15 |
| Alendronate Sodium | Alendronate Sodium | 46 | suppressed |
| Prednisone | Prednisone | 46 | 19 |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 45 | 30 |
| Risperidone | Risperidone | 45 | suppressed |
| Sucralfate | Sucralfate | 44 | suppressed |
| Ezetimibe | Ezetimibe | 40 | suppressed |
| Enulose | Lactulose | 38 | 11 |
| Hydrochlorothiazide | Hydrochlorothiazide | 37 | 11 |
| Paroxetine Hcl | Paroxetine Hcl | 37 | suppressed |
| Topiramate | Topiramate | 36 | suppressed |
| Torsemide | Torsemide | 36 | suppressed |
| Nystatin | Nystatin | 35 | 24 |
| Olanzapine | Olanzapine | 35 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 35 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 35 | 19 |
| Lacosamide | Lacosamide | 34 | suppressed |
| Oxcarbazepine | Oxcarbazepine | 34 | suppressed |
| Santyl | Collagenase Clostridium Hist. | 32 | 19 |
| Carbidopa-Levodopa | Carbidopa/Levodopa | 31 | suppressed |
| Sodium Chloride | 0.9 % Sodium Chloride | 31 | 19 |
| Azithromycin | Azithromycin | 30 | 19 |
| Glipizide | Glipizide | 29 | suppressed |
| Budesonide | Budesonide | 27 | suppressed |
| Insulin Lispro Kwikpen U-100 | Insulin Lispro | 27 | 11 |
| Novolog | Insulin Aspart | 27 | suppressed |
| Cefdinir | Cefdinir | 26 | 14 |
| Prednisolone Acetate | Prednisolone Acetate | 26 | suppressed |
| Meloxicam | Meloxicam | 25 | suppressed |
| Pioglitazone Hcl | Pioglitazone Hcl | 25 | suppressed |
| Benztropine Mesylate | Benztropine Mesylate | 24 | suppressed |
| Bupropion Hcl Sr | Bupropion Hcl | 24 | suppressed |
| Linzess | Linaclotide | 24 | suppressed |
| Timolol Maleate | Timolol Maleate | 24 | suppressed |
| Albuterol Sulfate | Albuterol Sulfate | 23 | 12 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 23 | 17 |
| Brimonidine Tartrate | Brimonidine Tartrate | 23 | suppressed |
| Lantus | Insulin Glargine,hum.Rec.Anlog | 23 | suppressed |
| Lorazepam | Lorazepam | 23 | 13 |
| Esomeprazole Magnesium | Esomeprazole Magnesium | 22 | suppressed |
| Isosorbide Mononitrate Er | Isosorbide Mononitrate | 22 | suppressed |
| Metoclopramide Hcl | Metoclopramide Hcl | 22 | suppressed |
| Cephalexin | Cephalexin | 21 | 16 |
| Dorzolamide-Timolol | Dorzolamide Hcl/Timolol Maleat | 21 | suppressed |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 21 | suppressed |
| Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate | 21 | suppressed |
| Amoxicillin | Amoxicillin | 19 | suppressed |
| Dorzolamide Hcl | Dorzolamide Hcl | 19 | suppressed |
| Doxycycline Hyclate | Doxycycline Hyclate | 19 | 13 |
| Fentanyl | Fentanyl | 19 | suppressed |
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 19 | suppressed |
| Atropine Sulfate | Atropine Sulfate | 18 | 11 |
| Bupropion Hcl | Bupropion Hcl | 18 | suppressed |
| Vascepa | Icosapent Ethyl | 18 | suppressed |
| Ceftriaxone | Ceftriaxone Sodium | 17 | suppressed |
| Enoxaparin Sodium | Enoxaparin Sodium | 17 | suppressed |
| Fluconazole | Fluconazole | 17 | 11 |
| Megestrol Acetate | Megestrol Acetate | 17 | suppressed |
| Methocarbamol | Methocarbamol | 17 | suppressed |
| Mirabegron Er | Mirabegron | 17 | suppressed |
| Nitrofurantoin | Nitrofurantoin Macrocrystal | 17 | suppressed |
| Phenobarbital | Phenobarbital | 17 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 17 | suppressed |
| Venlafaxine Hcl | Venlafaxine Hcl | 17 | suppressed |
| Clindamycin Hcl | Clindamycin Hcl | 16 | suppressed |
| Clonidine Hcl | Clonidine Hcl | 16 | suppressed |
| Glipizide Er | Glipizide | 16 | suppressed |
| Glucagon Emergency Kit | Glucagon | 16 | 11 |
| Methotrexate | Methotrexate Sodium | 16 | suppressed |
| Multaq | Dronedarone Hcl | 16 | suppressed |
| Nystop | Nystatin | 16 | 12 |
| Valproic Acid | Valproic Acid (As Sodium Salt) | 16 | suppressed |
| Daptomycin | Daptomycin | 15 | suppressed |
| Desipramine Hcl | Desipramine Hcl | 14 | suppressed |
| Dicyclomine Hcl | Dicyclomine Hcl | 14 | suppressed |
| Entresto | Sacubitril/Valsartan | 14 | suppressed |
| Fenofibrate | Fenofibrate | 14 | suppressed |
| Insulin Glargine-Yfgn | Insulin Glargine-Yfgn | 14 | suppressed |
| Lovastatin | Lovastatin | 14 | suppressed |
| Zolpidem Tartrate | Zolpidem Tartrate | 14 | suppressed |
| Admelog Solostar | Insulin Lispro | 13 | suppressed |
| Atenolol | Atenolol | 13 | suppressed |
| Dexamethasone | Dexamethasone | 13 | suppressed |
| Diclofenac Sodium | Diclofenac Sodium | 13 | 11 |
| Dilt-Xr | Diltiazem Hcl | 13 | suppressed |
| Metformin Hcl Er | Metformin Hcl | 13 | suppressed |
| Nateglinide | Nateglinide | 13 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 13 | suppressed |
| Triamcinolone Acetonide | Triamcinolone Acetonide | 13 | suppressed |
| Vitamin D2 | Ergocalciferol (Vitamin D2) | 13 | suppressed |
| Celecoxib | Celecoxib | 12 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 12 | suppressed |
| Fludrocortisone Acetate | Fludrocortisone Acetate | 12 | suppressed |
| Glipizide-Metformin | Glipizide/Metformin Hcl | 12 | suppressed |
| Hydrocortisone | Hydrocortisone | 12 | suppressed |
| Insulin Lispro | Insulin Lispro | 12 | suppressed |
| Oxycodone Hcl | Oxycodone Hcl | 12 | suppressed |
| Ramipril | Ramipril | 12 | suppressed |
| Temazepam | Temazepam | 12 | suppressed |
| Toujeo Solostar | Insulin Glargine,hum.Rec.Anlog | 12 | suppressed |
| Amitriptyline Hcl | Amitriptyline Hcl | 11 | suppressed |
| Humalog | Insulin Lispro | 11 | suppressed |
| Ibuprofen | Ibuprofen | 11 | suppressed |
| Ketoconazole | Ketoconazole | 11 | suppressed |
| Memantine Hcl Er | Memantine Hcl | 11 | suppressed |
| Meropenem | Meropenem | 11 | suppressed |
| Neomycin-Polymyxin-Dexameth | Neomycin/Polymyxin B/Dexametha | 11 | suppressed |
| Novolin R | Insulin Regular, Human | 11 | suppressed |
| Novolog Flexpen | Insulin Aspart | 11 | suppressed |
| Phenytoin | Phenytoin | 11 | suppressed |
| Triamterene-Hydrochlorothiazid | Triamterene/Hydrochlorothiazid | 11 | suppressed |
| Zenpep | Lipase/Protease/Amylase | 11 | suppressed |
Timeline
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $19.65 · 1 records | Otsuka America Pharmaceutical, Inc. | REXULTI | — | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error