Healthcare provider profile · identity verified

Larry Madison Ryle, M.D.

Internal Medicine · SHEPHERDSVILLE, KY · NPI 1538295845

Profile state: partd only Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

We did not find matching Open Payments records for this doctor in 2025.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

We did not find matching Open Payments records for this doctor in the selected program year.

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Analysis 1 · Payment-linked products

Products named in Open Payments records

No payment-linked product analysis is available because no matching General Payment records were found for the selected year.

Public prescribing for products named in payments

There is no explicit payment-product set available for a Part D comparison.

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

There is no payer-company set available for this comparison.

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

Brand	Generic	Claims	Beneficiaries
Atorvastatin Calcium	Atorvastatin Calcium	627	182
Amlodipine Besylate	Amlodipine Besylate	332	99
Levothyroxine Sodium	Levothyroxine Sodium	296	81
Pantoprazole Sodium	Pantoprazole Sodium	291	97
Losartan Potassium	Losartan Potassium	278	75
Metformin Hcl	Metformin Hcl	255	86
Furosemide	Furosemide	225	71
Gabapentin	Gabapentin	221	67
Lisinopril	Lisinopril	219	76
Rosuvastatin Calcium	Rosuvastatin Calcium	208	66
Metoprolol Succinate	Metoprolol Succinate	205	54
Omeprazole	Omeprazole	187	53
Duloxetine Hcl	Duloxetine Hcl	166	50
Hydrocodone-Acetaminophen	Hydrocodone/Acetaminophen	164	24
Simvastatin	Simvastatin	163	48
Carvedilol	Carvedilol	159	47
Metformin Hcl Er	Metformin Hcl	158	53
Albuterol Sulfate Hfa	Albuterol Sulfate	152	52
Ozempic	Semaglutide	150	34
Potassium Chloride	Potassium Chloride	150	41
Jardiance	Empagliflozin	144	43
Losartan-Hydrochlorothiazide	Losartan/Hydrochlorothiazide	130	40
Eliquis	Apixaban	119	27
Meloxicam	Meloxicam	119	36
Allopurinol	Allopurinol	113	38
Tamsulosin Hcl	Tamsulosin Hcl	112	45
Sertraline Hcl	Sertraline Hcl	111	40
Fluticasone Propionate	Fluticasone Propionate	108	42
Glimepiride	Glimepiride	106	29
Montelukast Sodium	Montelukast Sodium	105	28
Alprazolam	Alprazolam	104	16
Metoprolol Tartrate	Metoprolol Tartrate	102	34
Trazodone Hcl	Trazodone Hcl	96	32
Clopidogrel	Clopidogrel Bisulfate	93	29
Zolpidem Tartrate	Zolpidem Tartrate	92	16
Tizanidine Hcl	Tizanidine Hcl	88	37
Mounjaro	Tirzepatide	87	25
Venlafaxine Hcl Er	Venlafaxine Hcl	78	21
Hydroxyzine Hcl	Hydroxyzine Hcl	75	26
Escitalopram Oxalate	Escitalopram Oxalate	74	22
Hydrochlorothiazide	Hydrochlorothiazide	72	26
Valsartan-Hydrochlorothiazide	Valsartan/Hydrochlorothiazide	71	21
Levocetirizine Dihydrochloride	Levocetirizine Dihydrochloride	64	26
Pravastatin Sodium	Pravastatin Sodium	64	21
Diclofenac Sodium	Diclofenac Sodium	63	27
Cyclobenzaprine Hcl	Cyclobenzaprine Hcl	61	17
Isosorbide Mononitrate Er	Isosorbide Mononitrate	60	16
Pregabalin	Pregabalin	58	18
Methylprednisolone	Methylprednisolone	57	49
Alendronate Sodium	Alendronate Sodium	56	21
Celecoxib	Celecoxib	55	18
Clonazepam	Clonazepam	55	suppressed
Fluoxetine Hcl	Fluoxetine Hcl	55	13
Pioglitazone Hcl	Pioglitazone Hcl	54	16
Warfarin Sodium	Warfarin Sodium	54	12
Famotidine	Famotidine	52	20
Lisinopril-Hydrochlorothiazide	Lisinopril/Hydrochlorothiazide	48	17
Mirtazapine	Mirtazapine	48	17
Trulicity	Dulaglutide	48	11
Doxycycline Hyclate	Doxycycline Hyclate	47	39
Fluconazole	Fluconazole	47	26
Valsartan	Valsartan	47	13
Finasteride	Finasteride	46	15
Ondansetron Odt	Ondansetron	45	22
Amitriptyline Hcl	Amitriptyline Hcl	44	13
Basaglar Kwikpen U-100	Insulin Glargine,hum.Rec.Anlog	43	suppressed
Synthroid	Levothyroxine Sodium	43	12
Prednisone	Prednisone	42	27
Azithromycin	Azithromycin	41	33
Glipizide	Glipizide	41	13
Lorazepam	Lorazepam	41	suppressed
Spironolactone	Spironolactone	41	17
Amoxicillin	Amoxicillin	40	31
Ezetimibe	Ezetimibe	40	15
Aripiprazole	Aripiprazole	38	suppressed
Temazepam	Temazepam	38	suppressed
Buspirone Hcl	Buspirone Hcl	37	11
Ibuprofen	Ibuprofen	36	14
Meclizine Hcl	Meclizine Hcl	36	14
Breo Ellipta	Fluticasone/Vilanterol	35	suppressed
Citalopram Hbr	Citalopram Hydrobromide	35	12
Tramadol Hcl	Tramadol Hcl	35	14
Bupropion Xl	Bupropion Hcl	33	13
Dextroamphetamine-Amphetamine	Dextroamphetamine/Amphetamine	33	suppressed
Esomeprazole Magnesium	Esomeprazole Magnesium	32	12
Lansoprazole	Lansoprazole	32	suppressed
Trelegy Ellipta	Fluticasone/Umeclidin/Vilanter	31	suppressed
Diazepam	Diazepam	30	11
Lantus Solostar	Insulin Glargine,hum.Rec.Anlog	30	18
Valacyclovir	Valacyclovir Hcl	30	16
Ventolin Hfa	Albuterol Sulfate	30	11
Hydroxyzine Pamoate	Hydroxyzine Pamoate	29	suppressed
Atenolol	Atenolol	28	11
Hydralazine Hcl	Hydralazine Hcl	28	12
Xarelto	Rivaroxaban	27	suppressed
Tresiba Flextouch U-200	Insulin Degludec	26	suppressed
Azelastine Hcl	Azelastine Hcl	25	13
Levetiracetam	Levetiracetam	25	suppressed
Promethazine Hcl	Promethazine Hcl	25	suppressed
Baclofen	Baclofen	24	12
Topiramate	Topiramate	24	suppressed
Lovastatin	Lovastatin	23	suppressed
Oxybutynin Chloride Er	Oxybutynin Chloride	23	suppressed
Butalbital-Acetaminophen-Caffe	Butalb/Acetaminophen/Caffeine	22	suppressed
Janumet Xr	Sitagliptin Phos/Metformin Hcl	22	suppressed
Mupirocin	Mupirocin	22	16
Primidone	Primidone	22	suppressed
Sumatriptan Succinate	Sumatriptan Succinate	22	suppressed
Chlorthalidone	Chlorthalidone	21	suppressed
Paroxetine Hcl	Paroxetine Hcl	21	suppressed
Triamterene-Hydrochlorothiazid	Triamterene/Hydrochlorothiazid	21	suppressed
Amlodipine Besylate-Benazepril	Amlodipine Besylate/Benazepril	20	suppressed
Glipizide Er	Glipizide	20	suppressed
Olanzapine	Olanzapine	20	suppressed
Premarin	Estrogens, Conjugated	20	suppressed
Sulfamethoxazole-Trimethoprim	Sulfamethoxazole/Trimethoprim	20	14
Acetaminophen-Codeine	Acetaminophen With Codeine	19	suppressed
Clonidine Hcl	Clonidine Hcl	19	suppressed
Toujeo Solostar	Insulin Glargine,hum.Rec.Anlog	19	suppressed
Alfuzosin Hcl Er	Alfuzosin Hcl	18	suppressed
Colchicine	Colchicine	18	suppressed
Estradiol	Estradiol	18	suppressed
Farxiga	Dapagliflozin Propanediol	18	suppressed
Levofloxacin	Levofloxacin	18	16
Quetiapine Fumarate	Quetiapine Fumarate	18	suppressed
Ropinirole Hcl	Ropinirole Hcl	18	suppressed
Tolterodine Tartrate Er	Tolterodine Tartrate	18	suppressed
Verapamil Er	Verapamil Hcl	18	suppressed
Amiodarone Hcl	Amiodarone Hcl	17	suppressed
Amoxicillin-Clavulanate Potass	Amoxicillin/Potassium Clav	17	16
Cephalexin	Cephalexin	17	14
Desvenlafaxine Succinate Er	Desvenlafaxine Succinate	17	suppressed
Metolazone	Metolazone	17	suppressed
Nabumetone	Nabumetone	17	suppressed
Nitrofurantoin Mono-Macro	Nitrofurantoin Monohyd/M-Cryst	17	15
Pramipexole Dihydrochloride	Pramipexole Di-Hcl	17	suppressed
Vitamin D2	Ergocalciferol (Vitamin D2)	17	suppressed
Dexlansoprazole Dr	Dexlansoprazole	16	suppressed
Ketoconazole	Ketoconazole	16	suppressed
Klor-Con M20	Potassium Chloride	16	suppressed
Nitroglycerin	Nitroglycerin	16	suppressed
Rexulti	Brexpiprazole	16	suppressed
Bumetanide	Bumetanide	15	suppressed
Colestipol Hcl	Colestipol Hcl	15	suppressed
Novolog Flexpen	Insulin Aspart	15	suppressed
Bisoprolol-Hydrochlorothiazide	Bisoprolol/Hydrochlorothiazide	14	suppressed
Donepezil Hcl	Donepezil Hcl	14	suppressed
Droplet Pen Needle	Pen Needle, Diabetic	14	suppressed
Gemfibrozil	Gemfibrozil	14	suppressed
Propranolol Hcl Er	Propranolol Hcl	14	suppressed
Toujeo Max Solostar	Insulin Glargine,hum.Rec.Anlog	14	suppressed
Tramadol Hcl-Acetaminophen	Tramadol Hcl/Acetaminophen	14	suppressed
Acyclovir	Acyclovir	13	suppressed
Combivent Respimat	Ipratropium/Albuterol Sulfate	13	suppressed
Diltiazem 24hr Er (Cd)	Diltiazem Hcl	13	suppressed
Eszopiclone	Eszopiclone	13	suppressed
Klor-Con M10	Potassium Chloride	13	suppressed
Lyrica	Pregabalin	13	suppressed
Mometasone Furoate	Mometasone Furoate	13	suppressed
Nuedexta	Dextromethorphan Hbr/Quinidine	13	suppressed
Olmesartan Medoxomil	Olmesartan Medoxomil	13	suppressed
Ondansetron Hcl	Ondansetron Hcl	13	suppressed
Testosterone	Testosterone	13	suppressed
Trimethoprim	Trimethoprim	13	suppressed
Clotrimazole-Betamethasone	Clotrimazole/Betamethasone Dip	12	suppressed
Diphenoxylate-Atropine	Diphenoxylate Hcl/Atropine	12	suppressed
Irbesartan	Irbesartan	12	suppressed
Januvia	Sitagliptin Phosphate	12	suppressed
Lubiprostone	Lubiprostone	12	suppressed
Paxlovid	Nirmatrelvir/Ritonavir	12	12
Anoro Ellipta	Umeclidinium Brm/Vilanterol Tr	11	suppressed
Bupropion Hcl Sr	Bupropion Hcl	11	suppressed
Bydureon Bcise	Exenatide Microspheres	11	suppressed
Cefdinir	Cefdinir	11	suppressed
Dicyclomine Hcl	Dicyclomine Hcl	11	suppressed
Dilantin	Phenytoin Sodium Extended	11	suppressed
Fenofibrate	Fenofibrate Nanocrystallized	11	suppressed
Hydroxychloroquine Sulfate	Hydroxychloroquine Sulfate	11	suppressed
Nano 2nd Gen Pen Needle	Pen Needle, Diabetic	11	suppressed
Roflumilast	Roflumilast	11	suppressed
Stiolto Respimat	Tiotropium Br/Olodaterol Hcl	11	suppressed
Zypitamag	Pitavastatin Magnesium	11	suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

Year	General Payments	Main payer	Explicit products	Company overlaps	Part D coverage
2025	—	—	—	—	—
2024	—	—	—	—	Complete

Questions to ask

Questions you could discuss with your doctor

Are there reasonable alternatives I should understand when we discuss treatment options?
How should I interpret the industry-payment records shown here in the context of my care?

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.

Loaded source releases

Dataset	Year	Publication	Source
CMS Open Payments — General Payments	2025	2026-06-30	Original source
Medicare Part D Prescribers by Provider and Drug	2024	2026-05-06	Original source
NPPES Data Dissemination V2	current / reference data	2026-08-10	Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error