Payment overview · 2025
General Payments
$2,399.47
85 reported records · 21 companies
Healthcare provider profile · identity verified
Patrick J Demarco, MD
Allopathic & Osteopathic Physicians|Allergy & Immunology|Allergy · ORANGE PARK, FL · NPI 1578598967
Verified facts
What the public records show
CMS Open Payments records show Patrick J Demarco, MD received $2,399.47 in general payments during 2025 across 85 reported records.
AstraZeneca Pharmaceuticals LP accounted for 21.8% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 27 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Orladeyo, Trelegy Ellipta, Xhance.
AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYMBICORT as an associated drug or biological on 71 records involving 51 distinct recipient NPIs. Public Medicare Part D data also shows 16 claims for Symbicort by this doctor in 2024.
BioCryst US Sales Co., LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ORLADEYO as an associated drug or biological on 6240 records involving 2093 distinct recipient NPIs. Public Medicare Part D data also shows 11 claims for Orladeyo by this doctor in 2024.
GlaxoSmithKline, LLC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRELEGY ELLIPTA as an associated drug or biological on 131532 records involving 37148 distinct recipient NPIs. Public Medicare Part D data also shows 129 claims for Trelegy Ellipta by this doctor in 2024.
Optinose US, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Xhance as an associated drug or biological on 10863 records involving 5058 distinct recipient NPIs. Public Medicare Part D data also shows 13 claims for Xhance by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $522.92 | 21.8% | 17 | 2025 |
| Regeneron Healthcare Solutions, Inc. | Unresolved — no canonical attribution shown | $402.61 | 16.8% | 15 | 2025 |
| CSL Behring | Unresolved — no canonical attribution shown | $232.70 | 9.7% | 5 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $229.29 | 9.6% | 5 | 2025 |
| Grifols USA, LLC | Unresolved — no canonical attribution shown | $144.52 | 6.0% | 12 | 2025 |
| GlaxoSmithKline, LLC. | Unresolved — no canonical attribution shown | $120.31 | 5.0% | 6 | 2025 |
| SANOFI-AVENTIS U.S. LLC | Unresolved — no canonical attribution shown | $99.95 | 4.2% | 1 | 2025 |
| Takeda Pharmaceuticals U.S.A., Inc. | Unresolved — no canonical attribution shown | $88.31 | 3.7% | 3 | 2025 |
| PFIZER INC. | Unresolved — no canonical attribution shown | $75.16 | 3.1% | 3 | 2025 |
| ALK-Abello, Inc | Unresolved — no canonical attribution shown | $67.06 | 2.8% | 3 | 2025 |
| Genentech USA, Inc. | Unresolved — no canonical attribution shown | $62.96 | 2.6% | 2 | 2025 |
| GENZYME CORPORATION | Unresolved — no canonical attribution shown | $57.48 | 2.4% | 2 | 2025 |
| Lilly USA, LLC | Unresolved — no canonical attribution shown | $55.77 | 2.3% | 2 | 2025 |
| Optinose US, Inc. | Unresolved — no canonical attribution shown | $48.79 | 2.0% | 2 | 2025 |
| Amgen Inc. | Unresolved — no canonical attribution shown | $34.00 | 1.4% | 1 | 2025 |
| BioCryst US Sales Co., LLC | Unresolved — no canonical attribution shown | $33.46 | 1.4% | 1 | 2025 |
| Pharming Healthcare, Inc. | Unresolved — no canonical attribution shown | $29.55 | 1.2% | 1 | 2025 |
| Azurity Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $24.49 | 1.0% | 1 | 2025 |
| Incyte Corporation | Unresolved — no canonical attribution shown | $24.30 | 1.0% | 1 | 2025 |
| GC Biopharma USA, Inc. | Unresolved — no canonical attribution shown | $23.76 | 1.0% | 1 | 2025 |
| Galderma Laboratories, L.P. | Unresolved — no canonical attribution shown | $22.08 | 0.9% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $2,258.75 | 82 |
| Education | $140.72 | 3 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| DUPIXENT Normalized: dupixent |
Biological | GENZYME CORPORATION, Regeneron Healthcare Solutions, Inc., SANOFI-AVENTIS U.S. LLC | $560.04 | 18 | 2025 |
Source payment records
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| FASENRA Normalized: fasenra |
Biological | AstraZeneca Pharmaceuticals LP | $405.78 | 12 | 2025 |
Source payment records
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| Hizentra Normalized: hizentra |
Biological | CSL Behring | $146.43 | 2 | 2025 |
Source payment records
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| Xembify Normalized: xembify |
Biological | Grifols USA, LLC | $134.88 | 11 | 2025 |
Source payment records
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| NUCALA Normalized: nucala |
Biological | GlaxoSmithKline, LLC. | $105.95 | 5 | 2025 |
Source payment records
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| CUVITRU Normalized: cuvitru |
Biological | Takeda Pharmaceuticals U.S.A., Inc. | $88.31 | 3 | 2025 |
Source payment records
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| CUTAQUIG Normalized: cutaquig |
Biological | PFIZER INC. | $75.16 | 3 | 2025 |
Source payment records
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| TEZSPIRE Normalized: tezspire |
Biological | AstraZeneca Pharmaceuticals LP | $71.67 | 3 | 2025 |
Source payment records
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| Grastek Normalized: grastek |
Drug | ALK-Abello, Inc | $67.06 | 3 | 2025 |
Source payment records
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| Odactra Normalized: odactra |
Drug | ALK-Abello, Inc | $67.06 | 3 | 2025 |
Source payment records
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| Ragwitek Normalized: ragwitek |
Drug | ALK-Abello, Inc | $67.06 | 3 | 2025 |
Source payment records
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| Xolair Normalized: xolair |
Biological | Genentech USA, Inc. | $62.96 | 2 | 2025 |
Source payment records
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| AIRSUPRA Normalized: airsupra |
Drug | AstraZeneca Pharmaceuticals LP | $59.48 | 3 | 2025 |
Source payment records
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| EBGLYSS Normalized: ebglyss |
Drug | Lilly USA, LLC | $55.77 | 2 | 2025 |
Source payment records
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| Andembry Normalized: andembry |
Biological | CSL Behring | $55.46 | 2 | 2025 |
Source payment records
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| PANZYGA Normalized: panzyga |
Biological | PFIZER INC. | $51.59 | 2 | 2025 |
Source payment records
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| Xhance Normalized: xhance |
Drug | Optinose US, Inc. | $48.79 | 2 | 2025 |
Source payment records
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| Rhapsido Normalized: rhapsido |
Drug | Novartis Pharmaceuticals Corporation | $47.18 | 2 | 2025 |
Source payment records
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| ORLADEYO Normalized: orladeyo |
Drug | BioCryst US Sales Co., LLC | $33.46 | 1 | 2025 |
Source payment records
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| Haegarda Normalized: haegarda |
Biological | CSL Behring | $30.81 | 1 | 2025 |
Source payment records
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| RUCONEST Normalized: ruconest |
Biological | Pharming Healthcare, Inc. | $29.55 | 1 | 2025 |
Source payment records
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| ALVESCO Normalized: alvesco |
Drug | Azurity Pharmaceuticals, Inc. | $24.49 | 1 | 2025 |
Source payment records
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| OPZELURA Normalized: opzelura |
Drug | Incyte Corporation | $24.30 | 1 | 2025 |
Source payment records
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| ALYGLO Normalized: alyglo |
Drug | GC Biopharma USA, Inc. | $23.76 | 1 | 2025 |
Source payment records
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| NEMLUVIO Normalized: nemluvio |
Drug | Galderma Laboratories, L.P. | $22.08 | 1 | 2025 |
Source payment records
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| TRELEGY ELLIPTA Normalized: trelegy ellipta |
Drug | GlaxoSmithKline, LLC. | $14.36 | 1 | 2025 |
Source payment records
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| Gamunex-C Normalized: gamunex c |
Biological | Grifols USA, LLC | $9.64 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| ORLADEYO orladeyo |
2025 | Orladeyo | 2024 | 11 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| TRELEGY ELLIPTA trelegy ellipta |
2025 | Trelegy Ellipta | 2024 | 129 | exact normalized | Medicare Part D |
| Xhance xhance |
2025 | Xhance | 2024 | 13 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| AstraZeneca Pharmaceuticals LP Exact reporting entity; no affiliate inference |
2025 | SYMBICORT open payments reported associated product |
CMS Open Payments — General Payments 71 supporting records · 51 recipient NPIs · example record 1206132610 |
Symbicort · 2024 Exact normalized brand match · 1 Part D row |
16 | suppressed by CMS |
| BioCryst US Sales Co., LLC Exact reporting entity; no affiliate inference |
2025 | ORLADEYO open payments reported associated product |
CMS Open Payments — General Payments 6240 supporting records · 2093 recipient NPIs · example record 1222001397 |
Orladeyo · 2024 Exact normalized brand match · 1 Part D row |
11 | suppressed by CMS |
| GlaxoSmithKline, LLC. Exact reporting entity; no affiliate inference |
2025 | TRELEGY ELLIPTA open payments reported associated product |
CMS Open Payments — General Payments 131532 supporting records · 37148 recipient NPIs · example record 1190332369 |
Trelegy Ellipta · 2024 Exact normalized brand match · 1 Part D row |
129 | 24 |
| Optinose US, Inc. Exact reporting entity; no affiliate inference |
2025 | Xhance open payments reported associated product |
CMS Open Payments — General Payments 10863 supporting records · 5058 recipient NPIs · example record 1163252000 |
Xhance · 2024 Exact normalized brand match · 1 Part D row |
13 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Fluticasone Propionate | Fluticasone Propionate | 198 | 74 |
| Montelukast Sodium | Montelukast Sodium | 165 | 51 |
| Ipratropium Bromide | Ipratropium Bromide | 131 | 49 |
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 129 | 24 |
| Azelastine Hcl | Azelastine Hcl | 124 | 52 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 101 | 51 |
| Levocetirizine Dihydrochloride | Levocetirizine Dihydrochloride | 67 | 25 |
| Breo Ellipta | Fluticasone/Vilanterol | 49 | suppressed |
| Spiriva Respimat | Tiotropium Bromide | 41 | 11 |
| Olopatadine Hcl | Olopatadine Hcl | 39 | 15 |
| Arnuity Ellipta | Fluticasone Furoate | 32 | suppressed |
| Azelastine-Fluticasone | Azelastine/Fluticasone | 32 | 11 |
| Epinephrine | Epinephrine | 31 | 27 |
| Prednisone | Prednisone | 31 | 15 |
| Famotidine | Famotidine | 26 | suppressed |
| Qvar Redihaler | Beclomethasone Dipropionate | 26 | suppressed |
| Ventolin Hfa | Albuterol Sulfate | 21 | suppressed |
| Advair Hfa | Fluticasone Propion/Salmeterol | 16 | suppressed |
| Symbicort | Budesonide/Formoterol Fumarate | 16 | suppressed |
| Xhance | Fluticasone Propionate | 13 | suppressed |
| Breyna | Budesonide/Formoterol Fumarate | 11 | suppressed |
| Orladeyo | Berotralstat Hydrochloride | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $2,399.47 · 85 records | AstraZeneca Pharmaceuticals LP | AIRSUPRA, ALVESCO, ALYGLO, Andembry, CUTAQUIG, CUVITRU, DUPIXENT, EBGLYSS, FASENRA, Gamunex-C, Grastek, Haegarda, Hizentra, NEMLUVIO, NUCALA, OPZELURA, ORLADEYO, Odactra, PANZYGA, RUCONEST, Ragwitek, Rhapsido, TEZSPIRE, TRELEGY ELLIPTA, Xembify, Xhance, Xolair | 4 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Orladeyo play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with AstraZeneca Pharmaceuticals LP?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error