Payment overview · 2025
General Payments
$14,318.48
36 reported records · 9 companies
Healthcare provider profile · identity verified
Dean G Karalis, MD
Allopathic & Osteopathic Physicians|Internal Medicine|Cardiovascular Disease · PHILADELPHIA, PA · NPI 1609849256
Verified facts
What the public records show
CMS Open Payments records show Dean G Karalis, MD received $14,318.48 in general payments during 2025 across 36 reported records.
Amgen Inc. accounted for 82.5% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 10 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Leqvio.
Novartis Pharmaceuticals Corporation reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ENTRESTO as an associated drug or biological on 9346 records involving 6254 distinct recipient NPIs. Public Medicare Part D data also shows 49 claims for Entresto by this doctor in 2024.
Novartis Pharmaceuticals Corporation reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LEQVIO as an associated drug or biological on 126702 records involving 33819 distinct recipient NPIs. Public Medicare Part D data also shows 12 claims for Leqvio by this doctor in 2024.
Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 35 claims for Ozempic by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Amgen Inc. | Unresolved — no canonical attribution shown | $11,808.45 | 82.5% | 14 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $1,860.29 | 13.0% | 5 | 2025 |
| Novo Nordisk Inc | Unresolved — no canonical attribution shown | $203.67 | 1.4% | 7 | 2025 |
| Cleerly, Inc. | Unresolved — no canonical attribution shown | $127.07 | 0.9% | 1 | 2025 |
| BridgeBio Pharma, Inc. | Unresolved — no canonical attribution shown | $106.35 | 0.7% | 1 | 2025 |
| Kestra Medical Technology Services, Inc. | Unresolved — no canonical attribution shown | $100.74 | 0.7% | 4 | 2025 |
| IDORSIA PHARMACEUTICALS US INC | Unresolved — no canonical attribution shown | $52.48 | 0.4% | 1 | 2025 |
| Regeneron Healthcare Solutions, Inc. | Unresolved — no canonical attribution shown | $36.44 | 0.2% | 2 | 2025 |
| Ionis Pharmaceuticals, Inc. | Unresolved — no canonical attribution shown | $22.99 | 0.2% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program | $11,200.50 | 5 |
| Consulting Fee | $1,800.00 | 1 |
| Food and Beverage | $1,224.50 | 28 |
| Education | $52.48 | 1 |
| Travel and Lodging | $41.00 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| REPATHA Normalized: repatha |
Biological | Amgen Inc. | $11,641.83 | 12 | 2025 |
Source payment records
|
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| LEQVIO Normalized: leqvio |
Drug | Novartis Pharmaceuticals Corporation | $1,860.29 | 5 | 2025 |
Source payment records
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| Wegovy Normalized: wegovy |
Drug | Novo Nordisk Inc | $203.67 | 7 | 2025 |
Source payment records
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| Cleerly Ischemia Normalized: cleerly ischemia |
Device | Cleerly, Inc. | $127.07 | 1 | 2025 |
Source payment records
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| Cleerly Labs Normalized: cleerly labs |
Device | Cleerly, Inc. | $127.07 | 1 | 2025 |
Source payment records
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| Attruby Normalized: attruby |
Drug | BridgeBio Pharma, Inc. | $106.35 | 1 | 2025 |
Source payment records
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| Assure WCD Normalized: assure wcd |
Device | Kestra Medical Technology Services, Inc. | $100.74 | 4 | 2025 |
Source payment records
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| Tryvio Normalized: tryvio |
Drug | IDORSIA PHARMACEUTICALS US INC | $52.48 | 1 | 2025 |
Source payment records
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| EVKEEZA Normalized: evkeeza |
Biological | Regeneron Healthcare Solutions, Inc. | $36.44 | 2 | 2025 |
Source payment records
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| TRYNGOLZA Normalized: tryngolza |
Drug | Ionis Pharmaceuticals, Inc. | $22.99 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| LEQVIO leqvio |
2025 | Leqvio | 2024 | 12 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Novartis Pharmaceuticals Corporation Exact reporting entity; no affiliate inference |
2025 | ENTRESTO open payments reported associated product |
CMS Open Payments — General Payments 9346 supporting records · 6254 recipient NPIs · example record 1200004797 |
Entresto · 2024 Exact normalized brand match · 1 Part D row |
49 | 13 |
| Novartis Pharmaceuticals Corporation Exact reporting entity; no affiliate inference |
2025 | LEQVIO open payments reported associated product |
CMS Open Payments — General Payments 126702 supporting records · 33819 recipient NPIs · example record 1200004747 |
Leqvio · 2024 Exact normalized brand match · 1 Part D row |
12 | suppressed by CMS |
| Novo Nordisk Inc Exact reporting entity; no affiliate inference |
2025 | Ozempic open payments reported associated product |
CMS Open Payments — General Payments 261625 supporting records · 77793 recipient NPIs · example record 1188130076 |
Ozempic · 2024 Exact normalized brand match · 1 Part D row |
35 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Ezetimibe | Ezetimibe | 672 | 218 |
| Atorvastatin Calcium | Atorvastatin Calcium | 619 | 168 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 617 | 195 |
| Amlodipine Besylate | Amlodipine Besylate | 356 | 113 |
| Metoprolol Succinate | Metoprolol Succinate | 305 | 85 |
| Eliquis | Apixaban | 268 | 62 |
| Carvedilol | Carvedilol | 177 | 53 |
| Losartan Potassium | Losartan Potassium | 177 | 51 |
| Repatha Sureclick | Evolocumab | 153 | 27 |
| Hydrochlorothiazide | Hydrochlorothiazide | 151 | 41 |
| Furosemide | Furosemide | 135 | 35 |
| Ranolazine Er | Ranolazine | 114 | 38 |
| Lisinopril | Lisinopril | 104 | 25 |
| Clopidogrel | Clopidogrel Bisulfate | 103 | 31 |
| Icosapent Ethyl | Icosapent Ethyl | 83 | 24 |
| Nitroglycerin | Nitroglycerin | 78 | 24 |
| Metoprolol Tartrate | Metoprolol Tartrate | 76 | 17 |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 70 | 22 |
| Xarelto | Rivaroxaban | 70 | 18 |
| Vascepa | Icosapent Ethyl | 67 | 15 |
| Mounjaro | Tirzepatide | 52 | suppressed |
| Entresto | Sacubitril/Valsartan | 49 | 13 |
| Repatha Pushtronex | Evolocumab | 48 | 13 |
| Isosorbide Mononitrate Er | Isosorbide Mononitrate | 43 | 14 |
| Spironolactone | Spironolactone | 43 | 13 |
| Olmesartan-Hydrochlorothiazide | Olmesartan/Hydrochlorothiazide | 41 | 12 |
| Ramipril | Ramipril | 40 | suppressed |
| Pravastatin Sodium | Pravastatin Sodium | 38 | 14 |
| Amiodarone Hcl | Amiodarone Hcl | 35 | 14 |
| Nexlizet | Bempedoic Acid/Ezetimibe | 35 | suppressed |
| Ozempic | Semaglutide | 35 | suppressed |
| Atenolol | Atenolol | 34 | suppressed |
| Nifedipine Er | Nifedipine | 34 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 33 | suppressed |
| Losartan-Hydrochlorothiazide | Losartan/Hydrochlorothiazide | 31 | suppressed |
| Praluent Pen | Alirocumab | 28 | 11 |
| Warfarin Sodium | Warfarin Sodium | 28 | suppressed |
| Omeprazole | Omeprazole | 26 | suppressed |
| Famotidine | Famotidine | 24 | suppressed |
| Valsartan | Valsartan | 24 | suppressed |
| Fenofibrate | Fenofibrate Nanocrystallized | 21 | suppressed |
| Levothyroxine Sodium | Levothyroxine Sodium | 20 | suppressed |
| Lorazepam | Lorazepam | 20 | suppressed |
| Pantoprazole Sodium | Pantoprazole Sodium | 20 | suppressed |
| Nebivolol Hcl | Nebivolol Hcl | 19 | suppressed |
| Omega-3 Acid Ethyl Esters | Omega-3 Acid Ethyl Esters | 19 | suppressed |
| Simvastatin | Simvastatin | 19 | suppressed |
| Torsemide | Torsemide | 19 | suppressed |
| Valsartan-Hydrochlorothiazide | Valsartan/Hydrochlorothiazide | 19 | suppressed |
| Dofetilide | Dofetilide | 17 | suppressed |
| Labetalol Hcl | Labetalol Hcl | 17 | suppressed |
| Repatha Syringe | Evolocumab | 13 | suppressed |
| Candesartan Cilexetil | Candesartan Cilexetil | 12 | suppressed |
| Lansoprazole | Lansoprazole | 12 | suppressed |
| Leqvio | Inclisiran Sodium | 12 | suppressed |
| Allopurinol | Allopurinol | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $14,318.48 · 36 records | Amgen Inc. | Assure WCD, Attruby, Cleerly Ischemia, Cleerly Labs, EVKEEZA, LEQVIO, REPATHA, TRYNGOLZA, Tryvio, Wegovy | 3 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Leqvio play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Novartis Pharmaceuticals Corporation?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error