Payment overview · 2025
General Payments
$1,184.95
56 reported records · 22 companies
Healthcare provider profile · identity verified
John Jeffries Wrenn, MD
Allopathic & Osteopathic Physicians|Urology · GREENSBORO, NC · NPI 1659372019
Verified facts
What the public records show
CMS Open Payments records show John Jeffries Wrenn, MD received $1,184.95 in general payments during 2025 across 56 reported records.
Dendreon Pharmaceuticals LLC accounted for 21.0% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 24 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Gemtesa, Orgovyx, Xtandi.
PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ORGOVYX as an associated drug or biological on 16373 records involving 6981 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Orgovyx by this doctor in 2024.
PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported XTANDI as an associated drug or biological on 19368 records involving 7657 distinct recipient NPIs. Public Medicare Part D data also shows 22 claims for Xtandi by this doctor in 2024.
Sumitomo Pharma America, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported GEMTESA as an associated drug or biological on 61692 records involving 22152 distinct recipient NPIs. Public Medicare Part D data also shows 156 claims for Gemtesa by this doctor in 2024.
Sumitomo Pharma America, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ORGOVYX as an associated drug or biological on 17129 records involving 6223 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Orgovyx by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Dendreon Pharmaceuticals LLC | Unresolved — no canonical attribution shown | $248.54 | 21.0% | 11 | 2025 |
| Merck Sharp & Dohme LLC | Unresolved — no canonical attribution shown | $174.20 | 14.7% | 8 | 2025 |
| Sumitomo Pharma America, Inc. | Unresolved — no canonical attribution shown | $114.42 | 9.7% | 6 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $100.65 | 8.5% | 4 | 2025 |
| PFIZER INC. | Unresolved — no canonical attribution shown | $99.53 | 8.4% | 5 | 2025 |
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $73.66 | 6.2% | 3 | 2025 |
| ABBVIE INC. | Unresolved — no canonical attribution shown | $53.04 | 4.5% | 3 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $39.84 | 3.4% | 2 | 2025 |
| Tempus AI, Inc | Unresolved — no canonical attribution shown | $29.36 | 2.5% | 1 | 2025 |
| UROGEN PHARMA, INC. | Unresolved — no canonical attribution shown | $27.44 | 2.3% | 1 | 2025 |
| IMMUNITYBIO, INC. | Unresolved — no canonical attribution shown | $27.24 | 2.3% | 1 | 2025 |
| PROGENICS PHARMACEUTICALS, INC. | Unresolved — no canonical attribution shown | $26.46 | 2.2% | 1 | 2025 |
| COLOPLAST CORP | Unresolved — no canonical attribution shown | $21.02 | 1.8% | 1 | 2025 |
| Cycle Pharmaceuticals Inc | Unresolved — no canonical attribution shown | $20.60 | 1.7% | 1 | 2025 |
| VERTEX PHARMACEUTICALS INCORPORATED | Unresolved — no canonical attribution shown | $20.36 | 1.7% | 1 | 2025 |
| Ferring Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $18.45 | 1.6% | 1 | 2025 |
| Laborie Medical Technologies Corp. | Unresolved — no canonical attribution shown | $17.69 | 1.5% | 1 | 2025 |
| Alnylam Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $14.77 | 1.2% | 1 | 2025 |
| Janssen Biotech, Inc. | Unresolved — no canonical attribution shown | $14.77 | 1.2% | 1 | 2025 |
| E.R. Squibb & Sons, L.L.C. | Unresolved — no canonical attribution shown | $14.59 | 1.2% | 1 | 2025 |
| Antares Pharma, Inc. | Unresolved — no canonical attribution shown | $14.28 | 1.2% | 1 | 2025 |
| Calyxo, Inc. | Unresolved — no canonical attribution shown | $14.04 | 1.2% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $1,184.95 | 56 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| PROVENGE Normalized: provenge |
Drug | Dendreon Pharmaceuticals LLC | $248.54 | 11 | 2025 |
Source payment records
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| KEYTRUDA Normalized: keytruda |
Biological | Merck Sharp & Dohme LLC | $149.69 | 7 | 2025 |
Source payment records
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| GEMTESA Normalized: gemtesa |
Drug | Sumitomo Pharma America, Inc. | $114.42 | 6 | 2025 |
Source payment records
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| PLUVICTO Normalized: pluvicto |
Drug | Novartis Pharmaceuticals Corporation | $100.65 | 4 | 2025 |
Source payment records
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| ORGOVYX Normalized: orgovyx |
Drug | PFIZER INC. | $99.53 | 5 | 2025 |
Source payment records
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| TALZENNA Normalized: talzenna |
Drug | PFIZER INC. | $99.53 | 5 | 2025 |
Source payment records
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| XTANDI Normalized: xtandi |
Drug | PFIZER INC. | $99.53 | 5 | 2025 |
Source payment records
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| LYNPARZA Normalized: lynparza |
Biological, Drug | AstraZeneca Pharmaceuticals LP, Merck Sharp & Dohme LLC | $98.17 | 4 | 2025 |
Source payment records
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| BOTOX Normalized: botox |
Biological | ABBVIE INC. | $53.04 | 3 | 2025 |
Source payment records
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| KEYTRUDA QLEX Normalized: keytruda qlex |
Biological | Merck Sharp & Dohme LLC | $46.41 | 2 | 2025 |
Source payment records
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| Nubeqa Normalized: nubeqa |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $39.84 | 2 | 2025 |
Source payment records
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| XT CDX Normalized: xt cdx |
Device | Tempus AI, Inc | $29.36 | 1 | 2025 |
Source payment records
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| JELMYTO Normalized: jelmyto |
Drug | UROGEN PHARMA, INC. | $27.44 | 1 | 2025 |
Source payment records
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| ANKTIVA Normalized: anktiva |
Drug | IMMUNITYBIO, INC. | $27.24 | 1 | 2025 |
Source payment records
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| PYLARIFY Normalized: pylarify |
Drug | PROGENICS PHARMACEUTICALS, INC. | $26.46 | 1 | 2025 |
Source payment records
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| Titan Normalized: titan |
Device | COLOPLAST CORP | $21.02 | 1 | 2025 |
Source payment records
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| Venxxiva Normalized: venxxiva |
Drug | Cycle Pharmaceuticals Inc | $20.60 | 1 | 2025 |
Source payment records
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| JOURNAVX Normalized: journavx |
Drug | VERTEX PHARMACEUTICALS INCORPORATED | $20.36 | 1 | 2025 |
Source payment records
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| ADSTILADRIN Normalized: adstiladrin |
Biological | Ferring Pharmaceuticals Inc. | $18.45 | 1 | 2025 |
Source payment records
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| Optilume BPH Drug Coated Balloon Catheter Normalized: optilume bph drug coated balloon catheter |
Device | Laborie Medical Technologies Corp. | $17.69 | 1 | 2025 |
Source payment records
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| GIVLAARI Normalized: givlaari |
Drug | Alnylam Pharmaceuticals Inc. | $14.77 | 1 | 2025 |
Source payment records
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| OPDIVO Normalized: opdivo |
Biological | E.R. Squibb & Sons, L.L.C. | $14.59 | 1 | 2025 |
Source payment records
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| XYOSTED Normalized: xyosted |
Drug | Antares Pharma, Inc. | $14.28 | 1 | 2025 |
Source payment records
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| CVAC ASPIRATION SYSTEM Normalized: cvac aspiration system |
Device | Calyxo, Inc. | $14.04 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| GEMTESA gemtesa |
2025 | Gemtesa | 2024 | 156 | exact normalized | Medicare Part D |
| ORGOVYX orgovyx |
2025 | Orgovyx | 2024 | 43 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| XTANDI xtandi |
2025 | Xtandi | 2024 | 22 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| PFIZER INC. Exact reporting entity; no affiliate inference |
2025 | ORGOVYX open payments reported associated product |
CMS Open Payments — General Payments 16373 supporting records · 6981 recipient NPIs · example record 1228794230 |
Orgovyx · 2024 Exact normalized brand match · 1 Part D row |
43 | suppressed by CMS |
| PFIZER INC. Exact reporting entity; no affiliate inference |
2025 | XTANDI open payments reported associated product |
CMS Open Payments — General Payments 19368 supporting records · 7657 recipient NPIs · example record 1228794230 |
Xtandi · 2024 Exact normalized brand match · 1 Part D row |
22 | suppressed by CMS |
| Sumitomo Pharma America, Inc. Exact reporting entity; no affiliate inference |
2025 | GEMTESA open payments reported associated product |
CMS Open Payments — General Payments 61692 supporting records · 22152 recipient NPIs · example record 1176593503 |
Gemtesa · 2024 Exact normalized brand match · 1 Part D row |
156 | 35 |
| Sumitomo Pharma America, Inc. Exact reporting entity; no affiliate inference |
2025 | ORGOVYX open payments reported associated product |
CMS Open Payments — General Payments 17129 supporting records · 6223 recipient NPIs · example record 1176593507 |
Orgovyx · 2024 Exact normalized brand match · 1 Part D row |
43 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Tamsulosin Hcl | Tamsulosin Hcl | 716 | 234 |
| Finasteride | Finasteride | 605 | 169 |
| Alfuzosin Hcl Er | Alfuzosin Hcl | 196 | 55 |
| Myrbetriq | Mirabegron | 185 | 48 |
| Silodosin | Silodosin | 184 | 61 |
| Gemtesa | Vibegron | 156 | 35 |
| Cephalexin | Cephalexin | 154 | 70 |
| Levofloxacin | Levofloxacin | 77 | 68 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 70 | 52 |
| Testosterone | Testosterone | 66 | 15 |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 65 | 38 |
| Testosterone Cypionate | Testosterone Cypionate | 65 | 14 |
| Estradiol | Estradiol | 64 | 29 |
| Doxazosin Mesylate | Doxazosin Mesylate | 63 | 19 |
| Solifenacin Succinate | Solifenacin Succinate | 63 | 20 |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 52 | 37 |
| Nitrofurantoin Mono-Macro | Nitrofurantoin Monohyd/M-Cryst | 45 | 32 |
| Trospium Chloride | Trospium Chloride | 44 | 16 |
| Doxycycline Hyclate | Doxycycline Hyclate | 43 | 21 |
| Orgovyx | Relugolix | 43 | suppressed |
| Trimethoprim | Trimethoprim | 43 | suppressed |
| Oxybutynin Chloride | Oxybutynin Chloride | 41 | 12 |
| Ampicillin Trihydrate | Ampicillin Trihydrate | 38 | 20 |
| Dutasteride | Dutasteride | 38 | 13 |
| Oxycodone-Acetaminophen | Oxycodone Hcl/Acetaminophen | 35 | 20 |
| Fluconazole | Fluconazole | 34 | 20 |
| Potassium Citrate Er | Potassium Citrate | 33 | suppressed |
| Nitrofurantoin | Nitrofurantoin Macrocrystal | 29 | suppressed |
| Nystatin | Nystatin | 28 | 23 |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 27 | 15 |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 23 | suppressed |
| Xtandi | Enzalutamide | 22 | suppressed |
| Diazepam | Diazepam | 20 | 18 |
| Premarin | Estrogens, Conjugated | 20 | suppressed |
| Cefdinir | Cefdinir | 17 | suppressed |
| Tadalafil | Tadalafil | 16 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 16 | 14 |
| Allopurinol | Allopurinol | 11 | suppressed |
| Metronidazole | Metronidazole | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $1,184.95 · 56 records | Dendreon Pharmaceuticals LLC | ADSTILADRIN, ANKTIVA, BOTOX, CVAC ASPIRATION SYSTEM, GEMTESA, GIVLAARI, JELMYTO, JOURNAVX, KEYTRUDA, KEYTRUDA QLEX, LYNPARZA, Nubeqa, OPDIVO, ORGOVYX, Optilume BPH Drug Coated Balloon Catheter, PLUVICTO, PROVENGE, PYLARIFY, TALZENNA, Titan, Venxxiva, XT CDX, XTANDI, XYOSTED | 4 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Gemtesa play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with PFIZER INC.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error