Payment overview · 2025
General Payments
$28.41
1 reported records · 1 companies
Healthcare provider profile · identity verified
Marian C Bryce, D.O.
Allopathic & Osteopathic Physicians|Internal Medicine|Geriatric Medicine · KNOXVILLE, TN · NPI 1720001811
Verified facts
What the public records show
CMS Open Payments records show Marian C Bryce, D.O. received $28.41 in general payments during 2025 across 1 reported records.
Otsuka America Pharmaceutical, Inc. accounted for 100.0% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 1 associated product.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Otsuka America Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $28.41 | 100.0% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $28.41 | 1 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| REXULTI Normalized: rexulti |
Drug | Otsuka America Pharmaceutical, Inc. | $28.41 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
No exact normalized or approved-alias overlap was found in the loaded Part D year. This does not mean the doctor never prescribed the product.
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
No publishable same-company prescribing overlap was found in the loaded Part D year. This does not mean the doctor never prescribed a drug reported elsewhere by a paying company.
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Atorvastatin Calcium | Atorvastatin Calcium | 561 | 152 |
| Eliquis | Apixaban | 551 | 98 |
| Amlodipine Besylate | Amlodipine Besylate | 419 | 95 |
| Levothyroxine Sodium | Levothyroxine Sodium | 361 | 98 |
| Pantoprazole Sodium | Pantoprazole Sodium | 317 | 103 |
| Furosemide | Furosemide | 237 | 86 |
| Metoprolol Tartrate | Metoprolol Tartrate | 234 | 62 |
| Lisinopril | Lisinopril | 226 | 53 |
| Sertraline Hcl | Sertraline Hcl | 207 | 53 |
| Tamsulosin Hcl | Tamsulosin Hcl | 202 | 63 |
| Quetiapine Fumarate | Quetiapine Fumarate | 199 | 48 |
| Carvedilol | Carvedilol | 185 | 64 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 169 | 60 |
| Buspirone Hcl | Buspirone Hcl | 155 | 33 |
| Mirtazapine | Mirtazapine | 144 | 51 |
| Xarelto | Rivaroxaban | 141 | 23 |
| Trazodone Hcl | Trazodone Hcl | 135 | 57 |
| Potassium Chloride | Potassium Chloride | 127 | 44 |
| Metoprolol Succinate | Metoprolol Succinate | 120 | 49 |
| Famotidine | Famotidine | 115 | 28 |
| Hydralazine Hcl | Hydralazine Hcl | 115 | 34 |
| Losartan Potassium | Losartan Potassium | 115 | 55 |
| Donepezil Hcl | Donepezil Hcl | 114 | 33 |
| Levetiracetam | Levetiracetam | 113 | 20 |
| Spironolactone | Spironolactone | 108 | 37 |
| Clopidogrel | Clopidogrel Bisulfate | 105 | 34 |
| Duloxetine Hcl | Duloxetine Hcl | 105 | 38 |
| Metformin Hcl | Metformin Hcl | 104 | 33 |
| Baclofen | Baclofen | 95 | 16 |
| Gabapentin | Gabapentin | 95 | 22 |
| Pravastatin Sodium | Pravastatin Sodium | 95 | 22 |
| Latanoprost | Latanoprost | 90 | 19 |
| Ondansetron Hcl | Ondansetron Hcl | 87 | 51 |
| Fluticasone Propionate | Fluticasone Propionate | 86 | 35 |
| Ipratropium-Albuterol | Ipratropium/Albuterol Sulfate | 83 | 20 |
| Omeprazole | Omeprazole | 81 | 31 |
| Memantine Hcl | Memantine Hcl | 80 | 24 |
| Escitalopram Oxalate | Escitalopram Oxalate | 67 | 27 |
| Diclofenac Sodium | Diclofenac Sodium | 66 | 19 |
| Carbidopa-Levodopa | Carbidopa/Levodopa | 65 | 13 |
| Insulin Glargine-Yfgn | Insulin Glargine-Yfgn | 65 | 27 |
| Trelegy Ellipta | Fluticasone/Umeclidin/Vilanter | 65 | suppressed |
| Ropinirole Hcl | Ropinirole Hcl | 60 | 15 |
| Finasteride | Finasteride | 59 | 20 |
| Novolin R | Insulin Regular, Human | 57 | 16 |
| Citalopram Hbr | Citalopram Hydrobromide | 55 | 20 |
| Fluoxetine Hcl | Fluoxetine Hcl | 55 | 13 |
| Lantus | Insulin Glargine,hum.Rec.Anlog | 55 | 11 |
| Montelukast Sodium | Montelukast Sodium | 55 | 21 |
| Insulin Lispro Kwikpen U-100 | Insulin Lispro | 51 | 15 |
| Nystatin | Nystatin | 51 | 23 |
| Prednisone | Prednisone | 47 | 16 |
| Allopurinol | Allopurinol | 45 | 15 |
| Midodrine Hcl | Midodrine Hcl | 45 | 15 |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 44 | 21 |
| Methocarbamol | Methocarbamol | 44 | 34 |
| Lactulose | Lactulose | 43 | suppressed |
| Wixela Inhub | Fluticasone Propion/Salmeterol | 40 | suppressed |
| Entresto | Sacubitril/Valsartan | 39 | 13 |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 39 | 20 |
| Torsemide | Torsemide | 39 | 18 |
| Isosorbide Mononitrate Er | Isosorbide Mononitrate | 38 | 14 |
| Simvastatin | Simvastatin | 38 | 15 |
| Glipizide | Glipizide | 37 | suppressed |
| Nifedipine Er | Nifedipine | 37 | 13 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 36 | 32 |
| Novolog Flexpen | Insulin Aspart | 36 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 35 | suppressed |
| Klor-Con 10 | Potassium Chloride | 35 | suppressed |
| Doxycycline Hyclate | Doxycycline Hyclate | 33 | 22 |
| Jardiance | Empagliflozin | 33 | suppressed |
| Budesonide | Budesonide | 32 | suppressed |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 32 | 13 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 32 | 15 |
| Ondansetron Odt | Ondansetron | 30 | 17 |
| Warfarin Sodium | Warfarin Sodium | 30 | suppressed |
| Amiodarone Hcl | Amiodarone Hcl | 29 | 15 |
| Divalproex Sodium | Divalproex Sodium | 29 | suppressed |
| Olanzapine | Olanzapine | 29 | suppressed |
| Diltiazem 24hr Er | Diltiazem Hcl | 26 | suppressed |
| Ezetimibe | Ezetimibe | 26 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 26 | suppressed |
| Valsartan | Valsartan | 26 | 13 |
| Clonidine Hcl | Clonidine Hcl | 25 | suppressed |
| Glimepiride | Glimepiride | 25 | suppressed |
| Hydrochlorothiazide | Hydrochlorothiazide | 25 | 11 |
| Levemir Flexpen | Insulin Detemir | 25 | suppressed |
| Brimonidine Tartrate | Brimonidine Tartrate | 24 | suppressed |
| Lagevrio (Eua) | Molnupiravir | 24 | 23 |
| Myrbetriq | Mirabegron | 24 | suppressed |
| Timolol Maleate | Timolol Maleate | 24 | suppressed |
| Bumetanide | Bumetanide | 23 | 13 |
| Fenofibrate | Fenofibrate | 23 | suppressed |
| Divalproex Sodium Er | Divalproex Sodium | 22 | suppressed |
| Janumet | Sitagliptin Phos/Metformin Hcl | 22 | suppressed |
| Meloxicam | Meloxicam | 22 | suppressed |
| Metformin Hcl Er | Metformin Hcl | 22 | suppressed |
| Nitroglycerin | Nitroglycerin | 22 | 15 |
| Cefuroxime | Cefuroxime Axetil | 21 | suppressed |
| Lamotrigine | Lamotrigine | 21 | suppressed |
| Nitrofurantoin Mono-Macro | Nitrofurantoin Monohyd/M-Cryst | 21 | 11 |
| Scopolamine | Scopolamine | 21 | suppressed |
| Benazepril Hcl | Benazepril Hcl | 20 | suppressed |
| Farxiga | Dapagliflozin Propanediol | 20 | 13 |
| Insulin Lispro | Insulin Lispro | 19 | 11 |
| Methotrexate | Methotrexate Sodium | 19 | suppressed |
| Oxybutynin Chloride | Oxybutynin Chloride | 19 | suppressed |
| Promethazine Hcl | Promethazine Hcl | 19 | suppressed |
| Venlafaxine Hcl | Venlafaxine Hcl | 19 | suppressed |
| Alendronate Sodium | Alendronate Sodium | 18 | suppressed |
| Bupropion Xl | Bupropion Hcl | 18 | suppressed |
| Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate | 18 | suppressed |
| Linzess | Linaclotide | 18 | suppressed |
| Bupropion Hcl Sr | Bupropion Hcl | 17 | suppressed |
| Cyclobenzaprine Hcl | Cyclobenzaprine Hcl | 17 | suppressed |
| Digoxin | Digoxin | 17 | suppressed |
| Sulfasalazine | Sulfasalazine | 17 | suppressed |
| Tradjenta | Linagliptin | 17 | suppressed |
| Matzim La | Diltiazem Hcl | 16 | suppressed |
| Nateglinide | Nateglinide | 16 | suppressed |
| Oxycodone-Acetaminophen | Oxycodone Hcl/Acetaminophen | 16 | suppressed |
| Amantadine | Amantadine Hcl | 15 | suppressed |
| Brimonidine Tartrate-Timolol | Brimonidine Tartrate/Timolol | 15 | suppressed |
| Creon | Lipase/Protease/Amylase | 15 | suppressed |
| Dapagliflozin | Dapagliflozin Propanediol | 15 | suppressed |
| Epidiolex | Cannabidiol (Cbd) | 15 | suppressed |
| Risperidone | Risperidone | 15 | suppressed |
| Sucralfate | Sucralfate | 15 | 12 |
| Topiramate | Topiramate | 15 | suppressed |
| Benzonatate | Benzonatate | 14 | suppressed |
| Breztri Aerosphere | Budesonide/Glycopyr/Formoterol | 14 | suppressed |
| Enalapril Maleate | Enalapril Maleate | 14 | suppressed |
| Ertapenem | Ertapenem Sodium | 14 | suppressed |
| Fluconazole | Fluconazole | 14 | 12 |
| Pentoxifylline | Pentoxifylline | 14 | suppressed |
| Pyridostigmine Bromide | Pyridostigmine Bromide | 14 | suppressed |
| Albuterol Sulfate | Albuterol Sulfate | 13 | suppressed |
| Ammonium Lactate | Ammonium Lactate | 13 | suppressed |
| Dicyclomine Hcl | Dicyclomine Hcl | 13 | suppressed |
| Effer-K | Potassium Bicarbonate/Cit Ac | 13 | suppressed |
| Levofloxacin | Levofloxacin | 13 | suppressed |
| Primidone | Primidone | 13 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 13 | suppressed |
| Acetic Acid | Acetic Acid | 12 | suppressed |
| Aripiprazole | Aripiprazole | 12 | suppressed |
| Autoshield Duo Pen Needle | Pen Needle,dual Safety,diabetc | 12 | suppressed |
| Clonidine | Clonidine | 12 | suppressed |
| Doxazosin Mesylate | Doxazosin Mesylate | 12 | suppressed |
| Doxepin Hcl | Doxepin Hcl | 12 | suppressed |
| Esomeprazole Magnesium | Esomeprazole Magnesium | 12 | suppressed |
| Sevelamer Carbonate | Sevelamer Carbonate | 12 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 12 | suppressed |
| Trulicity | Dulaglutide | 12 | suppressed |
| Benztropine Mesylate | Benztropine Mesylate | 11 | suppressed |
| Chlorpromazine Hcl | Chlorpromazine Hcl | 11 | suppressed |
| Dorzolamide Hcl | Dorzolamide Hcl | 11 | suppressed |
| Enoxaparin Sodium | Enoxaparin Sodium | 11 | suppressed |
| Fludrocortisone Acetate | Fludrocortisone Acetate | 11 | suppressed |
| Lorazepam | Lorazepam | 11 | suppressed |
| Paroxetine Hcl | Paroxetine Hcl | 11 | suppressed |
| Vancomycin Hcl | Vancomycin/Water For Inj (Peg) | 11 | suppressed |
| Vitamin D2 | Ergocalciferol (Vitamin D2) | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $28.41 · 1 records | Otsuka America Pharmaceutical, Inc. | REXULTI | — | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error