Healthcare provider profile · identity verified

Nicole Ryke, M.D.

Allopathic & Osteopathic Physicians|Family Medicine · FARMINGTON HILLS, MI · NPI 1730349895

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Nicole Ryke, M.D. received $888.54 in general payments during 2025 across 53 reported records.

Novo Nordisk Inc accounted for 28.8% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 30 associated products.

A separate comparison found the same explicitly named product in public Medicare Part D data: Jardiance, Mounjaro, Ozempic, Paxlovid, Rybelsus, Trelegy Ellipta.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYNTHROID as an associated drug or biological on 10655 records involving 4881 distinct recipient NPIs. Public Medicare Part D data also shows 30 claims for Synthroid by this doctor in 2024.

AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported FARXIGA as an associated drug or biological on 106133 records involving 42906 distinct recipient NPIs. Public Medicare Part D data also shows 11 claims for Farxiga by this doctor in 2024.

GlaxoSmithKline, LLC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRELEGY ELLIPTA as an associated drug or biological on 131532 records involving 37148 distinct recipient NPIs. Public Medicare Part D data also shows 24 claims for Trelegy Ellipta by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported JARDIANCE as an associated drug or biological on 47708 records involving 23833 distinct recipient NPIs. Public Medicare Part D data also shows 68 claims for Jardiance by this doctor in 2024.

Lilly USA, LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported MOUNJARO as an associated drug or biological on 186719 records involving 66436 distinct recipient NPIs. Public Medicare Part D data also shows 43 claims for Mounjaro by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 73 claims for Ozempic by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Rybelsus as an associated drug or biological on 161257 records involving 55409 distinct recipient NPIs. Public Medicare Part D data also shows 17 claims for Rybelsus by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 87112 records involving 36032 distinct recipient NPIs. Public Medicare Part D data also shows 47 claims for Eliquis by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported PAXLOVID as an associated drug or biological on 24465 records involving 15715 distinct recipient NPIs. Public Medicare Part D data also shows 25 claims for Paxlovid by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$888.54

53 reported records · 17 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
Novo Nordisk Inc Unresolved — no canonical attribution shown $255.7428.8%162025
Lilly USA, LLC Unresolved — no canonical attribution shown $129.1014.5%92025
GlaxoSmithKline, LLC. Unresolved — no canonical attribution shown $94.9910.7%62025
Dexcom, Inc. Unresolved — no canonical attribution shown $63.237.1%32025
PFIZER INC. Unresolved — no canonical attribution shown $49.575.6%32025
AstraZeneca Pharmaceuticals LP Unresolved — no canonical attribution shown $45.785.2%32025
Amgen Inc. Unresolved — no canonical attribution shown $37.484.2%22025
Astellas Pharma US Inc Unresolved — no canonical attribution shown $35.003.9%22025
Ethicon Inc. Unresolved — no canonical attribution shown $31.373.5%12025
Edwards Lifesciences Corporation Unresolved — no canonical attribution shown $29.973.4%12025
ABBVIE INC. Unresolved — no canonical attribution shown $21.182.4%12025
Actelion Pharmaceuticals US, Inc. Unresolved — no canonical attribution shown $21.092.4%12025
Phathom Pharmaceuticals, Inc. Unresolved — no canonical attribution shown $16.301.8%12025
Recor Medical Inc Unresolved — no canonical attribution shown $14.961.7%12025
ABIOMED Unresolved — no canonical attribution shown $14.561.6%12025
Exact Sciences Corporation Unresolved — no canonical attribution shown $14.311.6%12025
ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) Unresolved — no canonical attribution shown $13.911.6%12025

What were the payments for?

Payment categories

CategoryAmountRecords
Food and Beverage$888.5453

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
Ozempic
Normalized: ozempic
Drug Novo Nordisk Inc $178.48 10 2025
Source payment records
Rybelsus
Normalized: rybelsus
Drug Novo Nordisk Inc $158.46 9 2025
Source payment records
TRELEGY ELLIPTA
Normalized: trelegy ellipta
Drug GlaxoSmithKline, LLC. $94.99 6 2025
Source payment records
MOUNJARO
Normalized: mounjaro
Drug Lilly USA, LLC $78.00 6 2025
Source payment records
ZEPBOUND
Normalized: zepbound
Drug Lilly USA, LLC $78.00 6 2025
Source payment records
Wegovy
Normalized: wegovy
Drug Novo Nordisk Inc $77.26 6 2025
Source payment records
Dexcom G6 Transmitter
Normalized: dexcom g6 transmitter
Medical Supply Dexcom, Inc. $63.23 3 2025
Source payment records
REPATHA
Normalized: repatha
Biological Amgen Inc. $37.48 2 2025
Source payment records
Veozah
Normalized: veozah
Drug Astellas Pharma US Inc $35.00 2 2025
Source payment records
JARDIANCE
Normalized: jardiance
Drug Lilly USA, LLC $33.16 2 2025
Source payment records
Monarch Platform
Normalized: monarch platform
Device Ethicon Inc. $31.37 1 2025
Source payment records
ABRYSVO
Normalized: abrysvo
Biological PFIZER INC. $31.02 2 2025
Source payment records
COMIRNATY
Normalized: comirnaty
Biological PFIZER INC. $31.02 2 2025
Source payment records
PREVNAR 20
Normalized: prevnar 20
Biological PFIZER INC. $31.02 2 2025
Source payment records
Saxenda
Normalized: saxenda
Drug Novo Nordisk Inc $31.02 3 2025
Source payment records
AIRSUPRA
Normalized: airsupra
Drug AstraZeneca Pharmaceuticals LP $30.94 2 2025
Source payment records
AREXVY
Normalized: arexvy
Biological GlaxoSmithKline, LLC. $30.47 2 2025
Source payment records
Edwards SAPIEN 3 Ultra Transcatheter Heart Valve
Normalized: edwards sapien 3 ultra transcatheter heart valve
Device Edwards Lifesciences Corporation $29.97 1 2025
Source payment records
UBRELVY
Normalized: ubrelvy
Drug ABBVIE INC. $21.18 1 2025
Source payment records
OPSUMIT
Normalized: opsumit
Drug Actelion Pharmaceuticals US, Inc. $21.09 1 2025
Source payment records
UPTRAVI
Normalized: uptravi
Drug Actelion Pharmaceuticals US, Inc. $21.09 1 2025
Source payment records
NURTEC ODT
Normalized: nurtec odt
Drug PFIZER INC. $18.55 1 2025
Source payment records
PAXLOVID
Normalized: paxlovid
Drug PFIZER INC. $18.55 1 2025
Source payment records
KISUNLA
Normalized: kisunla
Drug Lilly USA, LLC $17.94 1 2025
Source payment records
OTEZLA
Normalized: otezla
Drug Amgen Inc. $17.28 1 2025
Source payment records
VOQUEZNA
Normalized: voquezna
Drug Phathom Pharmaceuticals, Inc. $16.30 1 2025
Source payment records
Paradise Ultrasound Renal Denervation System
Normalized: paradise ultrasound renal denervation system
Device Recor Medical Inc $14.96 1 2025
Source payment records
BREZTRI
Normalized: breztri
Drug AstraZeneca Pharmaceuticals LP $14.84 1 2025
Source payment records
The Cologuard Plus Collection Kit
Normalized: the cologuard plus collection kit
Device Exact Sciences Corporation $14.31 1 2025
Source payment records
CAPLYTA
Normalized: caplyta
Drug ITI, Inc. (d/b/a Intra-Cellular Therapies, Inc.) $13.91 1 2025
Source payment records

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
JARDIANCE
jardiance
2025 Jardiance 2024 68 exact normalized Medicare Part D
MOUNJARO
mounjaro
2025 Mounjaro 2024 43
Beneficiary count suppressed
exact normalized Medicare Part D
Ozempic
ozempic
2025 Ozempic 2024 73 exact normalized Medicare Part D
PAXLOVID
paxlovid
2025 Paxlovid 2024 25 exact normalized Medicare Part D
Rybelsus
rybelsus
2025 Rybelsus 2024 17
Beneficiary count suppressed
exact normalized Medicare Part D
TRELEGY ELLIPTA
trelegy ellipta
2025 Trelegy Ellipta 2024 24
Beneficiary count suppressed
exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 SYNTHROID
open payments reported associated product
CMS Open Payments — General Payments
10655 supporting records · 4881 recipient NPIs · example record 1201352636
Synthroid · 2024
Exact normalized brand match · 1 Part D row
30 suppressed by CMS
AstraZeneca Pharmaceuticals LP
Exact reporting entity; no affiliate inference
2025 FARXIGA
open payments reported associated product
CMS Open Payments — General Payments
106133 supporting records · 42906 recipient NPIs · example record 1206131362
Farxiga · 2024
Exact normalized brand match · 1 Part D row
11 suppressed by CMS
GlaxoSmithKline, LLC.
Exact reporting entity; no affiliate inference
2025 TRELEGY ELLIPTA
open payments reported associated product
CMS Open Payments — General Payments
131532 supporting records · 37148 recipient NPIs · example record 1190332369
Trelegy Ellipta · 2024
Exact normalized brand match · 1 Part D row
24 suppressed by CMS
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 JARDIANCE
open payments reported associated product
CMS Open Payments — General Payments
47708 supporting records · 23833 recipient NPIs · example record 1186464557
Jardiance · 2024
Exact normalized brand match · 1 Part D row
68 17
Lilly USA, LLC
Exact reporting entity; no affiliate inference
2025 MOUNJARO
open payments reported associated product
CMS Open Payments — General Payments
186719 supporting records · 66436 recipient NPIs · example record 1186464455
Mounjaro · 2024
Exact normalized brand match · 1 Part D row
43 suppressed by CMS
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Ozempic
open payments reported associated product
CMS Open Payments — General Payments
261625 supporting records · 77793 recipient NPIs · example record 1188130076
Ozempic · 2024
Exact normalized brand match · 1 Part D row
73 15
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Rybelsus
open payments reported associated product
CMS Open Payments — General Payments
161257 supporting records · 55409 recipient NPIs · example record 1188130076
Rybelsus · 2024
Exact normalized brand match · 1 Part D row
17 suppressed by CMS
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 ELIQUIS
open payments reported associated product
CMS Open Payments — General Payments
87112 supporting records · 36032 recipient NPIs · example record 1228794063
Eliquis · 2024
Exact normalized brand match · 1 Part D row
47 13
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 PAXLOVID
open payments reported associated product
CMS Open Payments — General Payments
24465 supporting records · 15715 recipient NPIs · example record 1228794432
Paxlovid · 2024
Exact normalized brand match · 1 Part D row
25 24

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Atorvastatin CalciumAtorvastatin Calcium533156
Amlodipine BesylateAmlodipine Besylate372106
Levothyroxine SodiumLevothyroxine Sodium31184
Rosuvastatin CalciumRosuvastatin Calcium27989
Losartan PotassiumLosartan Potassium26878
OmeprazoleOmeprazole21875
LisinoprilLisinopril18155
Alendronate SodiumAlendronate Sodium18046
SimvastatinSimvastatin16548
Pantoprazole SodiumPantoprazole Sodium15856
Sertraline HclSertraline Hcl15045
Metoprolol SuccinateMetoprolol Succinate14445
HydrochlorothiazideHydrochlorothiazide13841
AlprazolamAlprazolam12530
Fluticasone PropionateFluticasone Propionate12243
Metformin HclMetformin Hcl11334
Olmesartan MedoxomilOlmesartan Medoxomil8027
Potassium ChloridePotassium Chloride7724
FamotidineFamotidine7526
MeloxicamMeloxicam7526
OzempicSemaglutide7315
Losartan-HydrochlorothiazideLosartan/Hydrochlorothiazide7219
Triamterene-HydrochlorothiazidTriamterene/Hydrochlorothiazid7221
Zolpidem TartrateZolpidem Tartrate7112
JardianceEmpagliflozin6817
Albuterol Sulfate HfaAlbuterol Sulfate6425
Pravastatin SodiumPravastatin Sodium6421
Azelastine HclAzelastine Hcl5732
JanuviaSitagliptin Phosphate5713
Montelukast SodiumMontelukast Sodium5419
IbuprofenIbuprofen5222
Lisinopril-HydrochlorothiazideLisinopril/Hydrochlorothiazide5214
Citalopram HbrCitalopram Hydrobromide47suppressed
EliquisApixaban4713
Metformin Hcl ErMetformin Hcl4716
AzithromycinAzithromycin4639
Venlafaxine Hcl ErVenlafaxine Hcl4414
Amlodipine Besylate-BenazeprilAmlodipine Besylate/Benazepril43suppressed
MounjaroTirzepatide43suppressed
AllopurinolAllopurinol4213
CarvedilolCarvedilol4216
MethylprednisoloneMethylprednisolone4138
Tramadol HclTramadol Hcl41suppressed
ClopidogrelClopidogrel Bisulfate4015
GabapentinGabapentin3911
Olmesartan-HydrochlorothiazideOlmesartan/Hydrochlorothiazide38suppressed
CefuroximeCefuroxime Axetil3724
AtenololAtenolol3611
Bupropion XlBupropion Hcl33suppressed
GlimepirideGlimepiride32suppressed
SynthroidLevothyroxine Sodium30suppressed
SpironolactoneSpironolactone29suppressed
FurosemideFurosemide28suppressed
Sumatriptan SuccinateSumatriptan Succinate28suppressed
Trazodone HclTrazodone Hcl28suppressed
CelecoxibCelecoxib26suppressed
Lantus SolostarInsulin Glargine,hum.Rec.Anlog26suppressed
Metoprolol TartrateMetoprolol Tartrate25suppressed
PaxlovidNirmatrelvir/Ritonavir2524
Levocetirizine DihydrochlorideLevocetirizine Dihydrochloride24suppressed
Nifedipine ErNifedipine24suppressed
Propranolol Hcl ErPropranolol Hcl24suppressed
Trelegy ElliptaFluticasone/Umeclidin/Vilanter24suppressed
Diclofenac SodiumDiclofenac Sodium23suppressed
EzetimibeEzetimibe23suppressed
GlipizideGlipizide23suppressed
Oxycodone-AcetaminophenOxycodone Hcl/Acetaminophen23suppressed
ValacyclovirValacyclovir Hcl2211
Hydralazine HclHydralazine Hcl21suppressed
Nano 2nd Gen Pen NeedlePen Needle, Diabetic21suppressed
Tamsulosin HclTamsulosin Hcl20suppressed
Donepezil HclDonepezil Hcl19suppressed
Duloxetine HclDuloxetine Hcl19suppressed
Escitalopram OxalateEscitalopram Oxalate19suppressed
LovastatinLovastatin19suppressed
Benazepril HclBenazepril Hcl18suppressed
IndapamideIndapamide18suppressed
ValsartanValsartan18suppressed
Doxazosin MesylateDoxazosin Mesylate17suppressed
LansoprazoleLansoprazole17suppressed
RybelsusSemaglutide17suppressed
EstradiolEstradiol16suppressed
Fluoxetine HclFluoxetine Hcl16suppressed
Dicyclomine HclDicyclomine Hcl15suppressed
Esomeprazole MagnesiumEsomeprazole Magnesium15suppressed
MethocarbamolMethocarbamol1512
Paroxetine HclParoxetine Hcl15suppressed
Raloxifene HclRaloxifene Hcl15suppressed
RizatriptanRizatriptan Benzoate15suppressed
Benazepril-HydrochlorothiazideBenazepril/Hydrochlorothiazide14suppressed
BumetanideBumetanide14suppressed
Amoxicillin-Clavulanate PotassAmoxicillin/Potassium Clav1311
DigoxinDigoxin13suppressed
Spiriva RespimatTiotropium Bromide13suppressed
Triamcinolone AcetonideTriamcinolone Acetonide13suppressed
AcyclovirAcyclovir12suppressed
Hydrocodone-AcetaminophenHydrocodone/Acetaminophen12suppressed
HydrocortisoneHydrocortisone12suppressed
Memantine HclMemantine Hcl12suppressed
Bisoprolol FumarateBisoprolol Fumarate11suppressed
EszopicloneEszopiclone11suppressed
FarxigaDapagliflozin Propanediol11suppressed
Hydroxyzine HclHydroxyzine Hcl11suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $888.54 · 53 records Novo Nordisk Inc ABRYSVO, AIRSUPRA, AREXVY, BREZTRI, CAPLYTA, COMIRNATY, Dexcom G6 Transmitter, Edwards SAPIEN 3 Ultra Transcatheter Heart Valve, JARDIANCE, KISUNLA, MOUNJARO, Monarch Platform, NURTEC ODT, OPSUMIT, OTEZLA, Ozempic, PAXLOVID, PREVNAR 20, Paradise Ultrasound Renal Denervation System, REPATHA, Rybelsus, Saxenda, TRELEGY ELLIPTA, The Cologuard Plus Collection Kit, UBRELVY, UPTRAVI, VOQUEZNA, Veozah, Wegovy, ZEPBOUND 9
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error