Payment overview · 2025
General Payments
$199.13
2 reported records · 2 companies
Healthcare provider profile · identity verified
Mark Stephan Ostrem, MD
Allopathic & Osteopathic Physicians|Internal Medicine|Geriatric Medicine · QUINCY, MA · NPI 1811985633
Verified facts
What the public records show
CMS Open Payments records show Mark Stephan Ostrem, MD received $199.13 in general payments during 2025 across 2 reported records.
Neurocrine BioSciences, Inc. accounted for 55.0% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 2 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Ingrezza, Rexulti.
Neurocrine BioSciences, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported INGREZZA as an associated drug or biological on 126456 records involving 27390 distinct recipient NPIs. Public Medicare Part D data also shows 23 claims for Ingrezza by this doctor in 2024.
Otsuka America Pharmaceutical, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported NUEDEXTA as an associated drug or biological on 393 records involving 285 distinct recipient NPIs. Public Medicare Part D data also shows 25 claims for Nuedexta by this doctor in 2024.
Otsuka America Pharmaceutical, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported REXULTI as an associated drug or biological on 160756 records involving 46288 distinct recipient NPIs. Public Medicare Part D data also shows 57 claims for Rexulti by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| Neurocrine BioSciences, Inc. | Unresolved — no canonical attribution shown | $109.59 | 55.0% | 1 | 2025 |
| Otsuka America Pharmaceutical, Inc. | Unresolved — no canonical attribution shown | $89.54 | 45.0% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $199.13 | 2 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| INGREZZA Normalized: ingrezza |
Drug | Neurocrine BioSciences, Inc. | $109.59 | 1 | 2025 |
Source payment records
|
|||||
| REXULTI Normalized: rexulti |
Drug | Otsuka America Pharmaceutical, Inc. | $89.54 | 1 | 2025 |
Source payment records
|
|||||
* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| INGREZZA ingrezza |
2025 | Ingrezza | 2024 | 23 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| REXULTI rexulti |
2025 | Rexulti | 2024 | 57 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Neurocrine BioSciences, Inc. Exact reporting entity; no affiliate inference |
2025 | INGREZZA open payments reported associated product |
CMS Open Payments — General Payments 126456 supporting records · 27390 recipient NPIs · example record 1242766729 |
Ingrezza · 2024 Exact normalized brand match · 1 Part D row |
23 | suppressed by CMS |
| Otsuka America Pharmaceutical, Inc. Exact reporting entity; no affiliate inference |
2025 | NUEDEXTA open payments reported associated product |
CMS Open Payments — General Payments 393 supporting records · 285 recipient NPIs · example record 1227268901 |
Nuedexta · 2024 Exact normalized brand match · 1 Part D row |
25 | suppressed by CMS |
| Otsuka America Pharmaceutical, Inc. Exact reporting entity; no affiliate inference |
2025 | REXULTI open payments reported associated product |
CMS Open Payments — General Payments 160756 supporting records · 46288 recipient NPIs · example record 1227267708 |
Rexulti · 2024 Exact normalized brand match · 1 Part D row |
57 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Trazodone Hcl | Trazodone Hcl | 793 | 73 |
| Atorvastatin Calcium | Atorvastatin Calcium | 716 | 85 |
| Eliquis | Apixaban | 514 | 36 |
| Gabapentin | Gabapentin | 495 | 56 |
| Baclofen | Baclofen | 435 | 42 |
| Furosemide | Furosemide | 428 | 35 |
| Metformin Hcl | Metformin Hcl | 373 | 34 |
| Divalproex Sodium | Divalproex Sodium | 347 | 27 |
| Levothyroxine Sodium | Levothyroxine Sodium | 334 | 39 |
| Quetiapine Fumarate | Quetiapine Fumarate | 333 | 22 |
| Amlodipine Besylate | Amlodipine Besylate | 277 | 34 |
| Mirtazapine | Mirtazapine | 275 | 35 |
| Metoprolol Succinate | Metoprolol Succinate | 273 | 31 |
| Duloxetine Hcl | Duloxetine Hcl | 271 | 23 |
| Pantoprazole Sodium | Pantoprazole Sodium | 259 | 32 |
| Olanzapine | Olanzapine | 247 | 17 |
| Lisinopril | Lisinopril | 226 | 24 |
| Tamsulosin Hcl | Tamsulosin Hcl | 217 | 25 |
| Sertraline Hcl | Sertraline Hcl | 199 | 26 |
| Losartan Potassium | Losartan Potassium | 198 | 29 |
| Gemtesa | Vibegron | 185 | 12 |
| Omeprazole | Omeprazole | 184 | 27 |
| Warfarin Sodium | Warfarin Sodium | 183 | suppressed |
| Farxiga | Dapagliflozin Propanediol | 168 | suppressed |
| Clonazepam | Clonazepam | 161 | 16 |
| Escitalopram Oxalate | Escitalopram Oxalate | 153 | 17 |
| Myrbetriq | Mirabegron | 152 | 13 |
| Potassium Chloride | Potassium Chloride | 149 | 13 |
| Simvastatin | Simvastatin | 149 | 18 |
| Citalopram Hbr | Citalopram Hydrobromide | 142 | 11 |
| Lorazepam | Lorazepam | 139 | 20 |
| Famotidine | Famotidine | 134 | 16 |
| Levetiracetam | Levetiracetam | 134 | 14 |
| Metoprolol Tartrate | Metoprolol Tartrate | 131 | 14 |
| Fluticasone Propionate | Fluticasone Propionate | 127 | 21 |
| Lamotrigine | Lamotrigine | 107 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 105 | 11 |
| Buspirone Hcl | Buspirone Hcl | 104 | suppressed |
| Risperidone | Risperidone | 99 | suppressed |
| Donepezil Hcl | Donepezil Hcl | 96 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 93 | 12 |
| Diclofenac Sodium | Diclofenac Sodium | 89 | 21 |
| Ketoconazole | Ketoconazole | 88 | 28 |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 87 | suppressed |
| Enoxaparin Sodium | Enoxaparin Sodium | 86 | suppressed |
| Fluoxetine Hcl | Fluoxetine Hcl | 84 | suppressed |
| Xarelto | Rivaroxaban | 83 | suppressed |
| Sodium Chloride | Sodium Chloride Irrig Solution | 79 | 16 |
| Carbidopa-Levodopa | Carbidopa/Levodopa | 78 | 11 |
| Methenamine Hippurate | Methenamine Hippurate | 74 | suppressed |
| Clopidogrel | Clopidogrel Bisulfate | 73 | suppressed |
| Amantadine | Amantadine Hcl | 72 | suppressed |
| Carbamazepine Er | Carbamazepine | 70 | suppressed |
| Spironolactone | Spironolactone | 69 | suppressed |
| Nuplazid | Pimavanserin Tartrate | 67 | suppressed |
| Botox | Onabotulinumtoxina | 65 | 20 |
| Nyamyc | Nystatin | 65 | 26 |
| Trulicity | Dulaglutide | 65 | suppressed |
| Hydrochlorothiazide | Hydrochlorothiazide | 63 | suppressed |
| Bupropion Hcl Sr | Bupropion Hcl | 62 | suppressed |
| Latanoprost | Latanoprost | 62 | suppressed |
| Ondansetron Odt | Ondansetron | 62 | suppressed |
| Valproic Acid | Valproic Acid (As Sodium Salt) | 60 | suppressed |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 59 | suppressed |
| Tradjenta | Linagliptin | 59 | suppressed |
| Cefpodoxime Proxetil | Cefpodoxime Proxetil | 58 | 25 |
| Rexulti | Brexpiprazole | 57 | suppressed |
| Alendronate Sodium | Alendronate Sodium | 56 | suppressed |
| Carvedilol | Carvedilol | 56 | suppressed |
| Divalproex Sodium Er | Divalproex Sodium | 56 | suppressed |
| Ondansetron Hcl | Ondansetron Hcl | 55 | 22 |
| Jardiance | Empagliflozin | 54 | suppressed |
| Finasteride | Finasteride | 53 | suppressed |
| Carbamazepine | Carbamazepine | 52 | suppressed |
| Januvia | Sitagliptin Phosphate | 52 | suppressed |
| Prednisone | Prednisone | 52 | 12 |
| Brimonidine Tartrate | Brimonidine Tartrate | 51 | suppressed |
| Atenolol | Atenolol | 50 | suppressed |
| Midodrine Hcl | Midodrine Hcl | 48 | suppressed |
| Aripiprazole | Aripiprazole | 47 | suppressed |
| Doxycycline Hyclate | Doxycycline Hyclate | 47 | 14 |
| Ibuprofen | Ibuprofen | 47 | suppressed |
| Lantus | Insulin Glargine,hum.Rec.Anlog | 47 | suppressed |
| Oxycodone Hcl | Oxycodone Hcl | 47 | 12 |
| Vraylar | Cariprazine Hcl | 47 | suppressed |
| Enulose | Lactulose | 46 | suppressed |
| Meloxicam | Meloxicam | 46 | suppressed |
| Torsemide | Torsemide | 46 | suppressed |
| Zonisamide | Zonisamide | 46 | suppressed |
| Ipratropium-Albuterol | Ipratropium/Albuterol Sulfate | 45 | 17 |
| Olanzapine Odt | Olanzapine | 45 | suppressed |
| Pravastatin Sodium | Pravastatin Sodium | 45 | suppressed |
| Glipizide | Glipizide | 42 | suppressed |
| Metformin Hcl Er | Metformin Hcl | 42 | suppressed |
| Modafinil | Modafinil | 41 | suppressed |
| Santyl | Collagenase Clostridium Hist. | 40 | 18 |
| Cephalexin | Cephalexin | 39 | 20 |
| Haloperidol | Haloperidol | 39 | suppressed |
| Naproxen | Naproxen | 38 | suppressed |
| Oxcarbazepine | Oxcarbazepine | 38 | suppressed |
| Betamethasone Valerate | Betamethasone Valerate | 36 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 35 | suppressed |
| Potassium Citrate Er | Potassium Citrate | 34 | suppressed |
| Zolpidem Tartrate | Zolpidem Tartrate | 34 | suppressed |
| Chlorhexidine Gluconate | Chlorhexidine Gluconate | 33 | suppressed |
| Silver Sulfadiazine | Silver Sulfadiazine | 32 | 15 |
| Abrysvo | Rsv Vacc, Pref A And Pref B/Pf | 31 | 28 |
| Bupropion Xl | Bupropion Hcl | 31 | suppressed |
| Kesimpta Pen | Ofatumumab | 31 | suppressed |
| Hydralazine Hcl | Hydralazine Hcl | 30 | suppressed |
| Lansoprazole | Lansoprazole | 30 | suppressed |
| Memantine Hcl | Memantine Hcl | 30 | suppressed |
| Venlafaxine Hcl Er | Venlafaxine Hcl | 30 | suppressed |
| Doxycycline Monohydrate | Doxycycline Monohydrate | 28 | suppressed |
| Glimepiride | Glimepiride | 28 | suppressed |
| Venlafaxine Hcl | Venlafaxine Hcl | 28 | suppressed |
| Labetalol Hcl | Labetalol Hcl | 27 | suppressed |
| Mupirocin | Mupirocin | 27 | 15 |
| Prednisolone Acetate | Prednisolone Acetate | 27 | suppressed |
| Pregabalin | Pregabalin | 26 | suppressed |
| Trimethoprim | Trimethoprim | 26 | suppressed |
| Glatiramer Acetate | Glatiramer Acetate | 25 | suppressed |
| Invokana | Canagliflozin | 25 | suppressed |
| Nuedexta | Dextromethorphan Hbr/Quinidine | 25 | suppressed |
| Albuterol Sulfate | Albuterol Sulfate | 24 | suppressed |
| Metoclopramide Hcl | Metoclopramide Hcl | 24 | suppressed |
| Trintellix | Vortioxetine Hydrobromide | 24 | suppressed |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 23 | 13 |
| Ceftriaxone | Ceftriaxone Sodium | 23 | 15 |
| Clonidine Hcl | Clonidine Hcl | 23 | suppressed |
| Ingrezza | Valbenazine Tosylate | 23 | suppressed |
| Lacosamide | Lacosamide | 23 | suppressed |
| Lioresal Intrathecal | Baclofen | 23 | 12 |
| Loperamide | Loperamide Hcl | 23 | suppressed |
| Prazosin Hcl | Prazosin Hcl | 23 | suppressed |
| Risperdal Consta | Risperidone Microspheres | 23 | suppressed |
| Synthroid | Levothyroxine Sodium | 23 | suppressed |
| Basaglar Kwikpen U-100 | Insulin Glargine,hum.Rec.Anlog | 22 | suppressed |
| Carbidopa-Levodopa-Entacapone | Carbidopa/Levodopa/Entacapone | 22 | suppressed |
| Methimazole | Methimazole | 22 | suppressed |
| Methocarbamol | Methocarbamol | 22 | suppressed |
| Nitrofurantoin Mono-Macro | Nitrofurantoin Monohyd/M-Cryst | 22 | 14 |
| Timolol Maleate | Timolol Maleate | 22 | suppressed |
| Benztropine Mesylate | Benztropine Mesylate | 21 | suppressed |
| Carbidopa-Levodopa Er | Carbidopa/Levodopa | 21 | suppressed |
| Glipizide Er | Glipizide | 21 | suppressed |
| Lactulose | Lactulose | 21 | suppressed |
| Xifaxan | Rifaximin | 21 | suppressed |
| Betamethasone Dipropionate | Betamethasone Dipropionate | 20 | suppressed |
| Budesonide Er | Budesonide | 20 | suppressed |
| Haloperidol Lactate | Haloperidol Lactate | 20 | suppressed |
| Movantik | Naloxegol Oxalate | 20 | suppressed |
| Atropine Sulfate | Atropine Sulfate | 19 | suppressed |
| Azithromycin | Azithromycin | 19 | suppressed |
| Digoxin | Digoxin | 19 | suppressed |
| Doxepin Hcl | Doxepin Hcl | 19 | suppressed |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 19 | suppressed |
| Janumet | Sitagliptin Phos/Metformin Hcl | 19 | suppressed |
| Rytary | Carbidopa/Levodopa | 19 | suppressed |
| Clotrimazole | Clotrimazole | 18 | suppressed |
| Gentamicin Sulfate | Gentamicin Sulfate | 18 | suppressed |
| Semglee (Yfgn) Pen | Insulin Glargine-Yfgn | 18 | suppressed |
| Autoshield Duo Pen Needle | Pen Needle,dual Safety,diabetc | 17 | suppressed |
| Cholestyramine | Cholestyramine (With Sugar) | 17 | suppressed |
| Dapagliflozin | Dapagliflozin Propanediol | 17 | suppressed |
| Doxazosin Mesylate | Doxazosin Mesylate | 17 | suppressed |
| Entacapone | Entacapone | 17 | suppressed |
| Erythromycin | Erythromycin Base | 17 | suppressed |
| Lantus Solostar | Insulin Glargine,hum.Rec.Anlog | 17 | suppressed |
| Methylphenidate Hcl | Methylphenidate Hcl | 17 | suppressed |
| Valacyclovir | Valacyclovir Hcl | 17 | suppressed |
| Vancomycin Hcl | Vancomycin Hcl | 17 | suppressed |
| Metolazone | Metolazone | 16 | suppressed |
| Pulmicort Flexhaler | Budesonide | 16 | suppressed |
| Calcitriol | Calcitriol | 15 | suppressed |
| Lidocaine Hcl | Lidocaine Hcl | 15 | 14 |
| Lisinopril-Hydrochlorothiazide | Lisinopril/Hydrochlorothiazide | 15 | suppressed |
| Meclizine Hcl | Meclizine Hcl | 15 | suppressed |
| Pramipexole Dihydrochloride | Pramipexole Di-Hcl | 15 | suppressed |
| Copaxone | Glatiramer Acetate | 14 | suppressed |
| Kapspargo Sprinkle | Metoprolol Succinate | 14 | suppressed |
| Levofloxacin | Levofloxacin | 14 | 11 |
| Rebif Rebidose | Interferon Beta-1a/Albumin | 14 | suppressed |
| Rocklatan | Netarsudil Mesylat/Latanoprost | 14 | suppressed |
| Sucralfate | Sucralfate | 14 | suppressed |
| Breo Ellipta | Fluticasone/Vilanterol | 13 | suppressed |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 13 | suppressed |
| Creon | Lipase/Protease/Amylase | 13 | suppressed |
| Diazepam | Diazepam | 13 | suppressed |
| Diltiazem 24hr Er (Cd) | Diltiazem Hcl | 13 | suppressed |
| Fenofibrate | Fenofibrate | 13 | suppressed |
| Glatopa | Glatiramer Acetate | 13 | suppressed |
| Incruse Ellipta | Umeclidinium Bromide | 13 | suppressed |
| Methadone Hcl | Methadone Hcl | 13 | suppressed |
| Nortriptyline Hcl | Nortriptyline Hcl | 13 | suppressed |
| Olmesartan Medoxomil | Olmesartan Medoxomil | 13 | suppressed |
| Prempro | Estrogen,con/M-Progest Acet | 13 | suppressed |
| Selegiline Hcl | Selegiline Hcl | 13 | suppressed |
| Acetaminophen-Codeine | Acetaminophen With Codeine | 12 | suppressed |
| Acetylcysteine | Acetylcysteine | 12 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 12 | suppressed |
| Brinzolamide | Brinzolamide | 12 | suppressed |
| Clindamycin Phosphate | Clindamycin Phosphate | 12 | suppressed |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 12 | suppressed |
| Nystop | Nystatin | 12 | suppressed |
| Pioglitazone Hcl | Pioglitazone Hcl | 12 | suppressed |
| Primidone | Primidone | 12 | suppressed |
| Protonix | Pantoprazole Sodium | 12 | suppressed |
| Restasis | Cyclosporine | 12 | suppressed |
| Triamcinolone Acetonide | Triamcinolone Acetonide | 12 | suppressed |
| Valsartan | Valsartan | 12 | suppressed |
| Verapamil Hcl | Verapamil Hcl | 12 | suppressed |
| Biktarvy | Bictegrav/Emtricit/Tenofov Ala | 11 | suppressed |
| Bumetanide | Bumetanide | 11 | suppressed |
| Bupropion Hcl | Bupropion Hcl | 11 | suppressed |
| Dorzolamide-Timolol | Dorzolamide Hcl/Timolol Maleat | 11 | suppressed |
| Estradiol | Estradiol | 11 | suppressed |
| Fluphenazine Hcl | Fluphenazine Hcl | 11 | suppressed |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 11 | suppressed |
| Hydroxychloroquine Sulfate | Hydroxychloroquine Sulfate | 11 | suppressed |
| Nadolol | Nadolol | 11 | suppressed |
| Paroxetine Hcl | Paroxetine Hcl | 11 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 11 | suppressed |
| Teriflunomide | Teriflunomide | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $199.13 · 2 records | Neurocrine BioSciences, Inc. | INGREZZA, REXULTI | 3 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Ingrezza play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Neurocrine BioSciences, Inc.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error