Healthcare provider profile · identity verified

Mark R Freije, MD

Allopathic & Osteopathic Physicians|Family Medicine · CARMEL, IN · NPI 1932317849

Profile state: payments and partd Open Payments: 2025 Medicare Part D: 2024 Last identity check: 2026-08-10 Page data build: 2026-08-12

Verified facts

What the public records show

CMS Open Payments records show Mark R Freije, MD received $733.47 in general payments during 2025 across 39 reported records.

AstraZeneca Pharmaceuticals LP accounted for 18.6% of that reported general-payment amount.

The Open Payments records used for this analysis explicitly named 23 associated products.

A separate comparison found the same explicitly named product in public Medicare Part D data: Farxiga, Ozempic, Rybelsus, Trelegy Ellipta.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported LINZESS as an associated drug or biological on 87954 records involving 21815 distinct recipient NPIs. Public Medicare Part D data also shows 20 claims for Linzess by this doctor in 2024.

ABBVIE INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported SYNTHROID as an associated drug or biological on 10655 records involving 4881 distinct recipient NPIs. Public Medicare Part D data also shows 37 claims for Synthroid by this doctor in 2024.

AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported BEVESPI AEROSPHERE as an associated drug or biological on 763 records involving 473 distinct recipient NPIs. Public Medicare Part D data also shows 15 claims for Bevespi Aerosphere by this doctor in 2024.

AstraZeneca Pharmaceuticals LP reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported FARXIGA as an associated drug or biological on 106133 records involving 42906 distinct recipient NPIs. Public Medicare Part D data also shows 46 claims for Farxiga by this doctor in 2024.

GlaxoSmithKline, LLC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported TRELEGY ELLIPTA as an associated drug or biological on 131532 records involving 37148 distinct recipient NPIs. Public Medicare Part D data also shows 33 claims for Trelegy Ellipta by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Ozempic as an associated drug or biological on 261625 records involving 77793 distinct recipient NPIs. Public Medicare Part D data also shows 45 claims for Ozempic by this doctor in 2024.

Novo Nordisk Inc reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Rybelsus as an associated drug or biological on 161257 records involving 55409 distinct recipient NPIs. Public Medicare Part D data also shows 11 claims for Rybelsus by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 87112 records involving 36032 distinct recipient NPIs. Public Medicare Part D data also shows 99 claims for Eliquis by this doctor in 2024.

PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported PAXLOVID as an associated drug or biological on 24465 records involving 15715 distinct recipient NPIs. Public Medicare Part D data also shows 15 claims for Paxlovid by this doctor in 2024.

These records do not establish that a payment influenced prescribing or medical care.

Payment overview · 2025

General Payments

$733.47

39 reported records · 17 companies

Separate record types

Research & Ownership

Research Payments (direct recipient): not present in the loaded data

Associated Research Funding (for example, named PI): not present in the loaded data

Ownership / Investment: not present in the loaded data

These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.

Who paid this doctor?

Companies in 2025 General Payments

Reported companyCanonical companyAmountShareRecordsYear
AstraZeneca Pharmaceuticals LP Unresolved — no canonical attribution shown $136.2518.6%72025
Novo Nordisk Inc Unresolved — no canonical attribution shown $127.1817.3%72025
Sumitomo Pharma America, Inc. Unresolved — no canonical attribution shown $64.358.8%32025
Corium, LLC Unresolved — no canonical attribution shown $63.778.7%42025
ABBVIE INC. Unresolved — no canonical attribution shown $51.607.0%22025
PFIZER INC. Unresolved — no canonical attribution shown $37.775.2%22025
Abbott Laboratories Unresolved — no canonical attribution shown $37.365.1%22025
Exact Sciences Corporation Unresolved — no canonical attribution shown $35.934.9%22025
GlaxoSmithKline, LLC. Unresolved — no canonical attribution shown $32.974.5%22025
Amgen Inc. Unresolved — no canonical attribution shown $24.593.4%12025
Salix Pharmaceuticals, a division of Bausch Health US, LLC Unresolved — no canonical attribution shown $22.823.1%12025
Bayer Healthcare Pharmaceuticals Inc. Unresolved — no canonical attribution shown $22.633.1%12025
Otsuka America Pharmaceutical, Inc. Unresolved — no canonical attribution shown $19.622.7%12025
Lundbeck LLC Unresolved — no canonical attribution shown $17.552.4%12025
Kowa Pharmaceuticals America, Inc. Unresolved — no canonical attribution shown $14.812.0%12025
Dynavax Technologies Corporation Unresolved — no canonical attribution shown $13.171.8%12025
MAYNE PHARMA COMMERCIAL LLC Unresolved — no canonical attribution shown $11.101.5%12025

What were the payments for?

Payment categories

CategoryAmountRecords
Food and Beverage$733.4739

A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.

Analysis 1 · Payment-linked products

Products named in Open Payments records

Reported productTypeReported companyRelated amount*RecordsYear
Ozempic
Normalized: ozempic
Drug Novo Nordisk Inc $80.49 4 2025
Source payment records
AIRSUPRA
Normalized: airsupra
Drug AstraZeneca Pharmaceuticals LP $68.96 3 2025
Source payment records
FARXIGA
Normalized: farxiga
Drug AstraZeneca Pharmaceuticals LP $67.29 4 2025
Source payment records
GEMTESA
Normalized: gemtesa
Drug Sumitomo Pharma America, Inc. $64.35 3 2025
Source payment records
Azstarys
Normalized: azstarys
Drug Corium, LLC $63.77 4 2025
Source payment records
QULIPTA
Normalized: qulipta
Drug ABBVIE INC. $51.60 2 2025
Source payment records
UBRELVY
Normalized: ubrelvy
Drug ABBVIE INC. $51.60 2 2025
Source payment records
Rybelsus
Normalized: rybelsus
Drug Novo Nordisk Inc $41.76 2 2025
Source payment records
ABRYSVO
Normalized: abrysvo
Biological PFIZER INC. $37.77 2 2025
Source payment records
COMIRNATY
Normalized: comirnaty
Biological PFIZER INC. $37.77 2 2025
Source payment records
PREVNAR 20
Normalized: prevnar 20
Biological PFIZER INC. $37.77 2 2025
Source payment records
FREESTYLE LIBRE 3
Normalized: freestyle libre 3
Device Abbott Laboratories $37.36 2 2025
Source payment records
REXULTI
Normalized: rexulti
Drug Lundbeck LLC, Otsuka America Pharmaceutical, Inc. $37.17 2 2025
Source payment records
BREZTRI
Normalized: breztri
Drug AstraZeneca Pharmaceuticals LP $34.34 1 2025
Source payment records
TRELEGY ELLIPTA
Normalized: trelegy ellipta
Drug GlaxoSmithKline, LLC. $32.97 2 2025
Source payment records
Wegovy
Normalized: wegovy
Drug Novo Nordisk Inc $32.53 2 2025
Source payment records
EVENITY
Normalized: evenity
Biological Amgen Inc. $24.59 1 2025
Source payment records
XIFAXAN
Normalized: xifaxan
Drug Salix Pharmaceuticals, a division of Bausch Health US, LLC $22.82 1 2025
Source payment records
  • 2025-07-08 · Salix Pharmaceuticals, a division of Bausch Health US, LLC · $22.82 · Open Payments source
Kerendia
Normalized: kerendia
Drug Bayer Healthcare Pharmaceuticals Inc. $22.63 1 2025
Source payment records
The Cologuard Plus Collection Kit
Normalized: the cologuard plus collection kit
Device Exact Sciences Corporation $18.87 1 2025
Source payment records
Cologuard Collection Kit
Normalized: cologuard collection kit
Device Exact Sciences Corporation $17.06 1 2025
Source payment records
ZORYVE
Normalized: zoryve
Drug Kowa Pharmaceuticals America, Inc. $14.81 1 2025
Source payment records
Heplisav-B
Normalized: heplisav b
Drug Dynavax Technologies Corporation $13.17 1 2025
Source payment records

* Product-associated amounts are non-additive because one payment record may name more than one product.

These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.

Public prescribing for products named in payments

Open Payments productPayment yearPart D brandPart D yearClaimsMatch methodSource
FARXIGA
farxiga
2025 Farxiga 2024 46
Beneficiary count suppressed
exact normalized Medicare Part D
Ozempic
ozempic
2025 Ozempic 2024 45
Beneficiary count suppressed
exact normalized Medicare Part D
Rybelsus
rybelsus
2025 Rybelsus 2024 11
Beneficiary count suppressed
exact normalized Medicare Part D
TRELEGY ELLIPTA
trelegy ellipta
2025 Trelegy Ellipta 2024 33
Beneficiary count suppressed
exact normalized Medicare Part D

The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.

Analysis 2 · Same-company prescribing overlap

Drugs reported in other payments from the same company that also appear in Medicare Part D

This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.

Paying companyPayment yearDrug reported by same entityOpen Payments evidencePart DClaimsBeneficiaries
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 LINZESS
open payments reported associated product
CMS Open Payments — General Payments
87954 supporting records · 21815 recipient NPIs · example record 1201352608
Linzess · 2024
Exact normalized brand match · 1 Part D row
20 suppressed by CMS
ABBVIE INC.
Exact reporting entity; no affiliate inference
2025 SYNTHROID
open payments reported associated product
CMS Open Payments — General Payments
10655 supporting records · 4881 recipient NPIs · example record 1201352636
Synthroid · 2024
Exact normalized brand match · 1 Part D row
37 suppressed by CMS
AstraZeneca Pharmaceuticals LP
Exact reporting entity; no affiliate inference
2025 BEVESPI AEROSPHERE
open payments reported associated product
CMS Open Payments — General Payments
763 supporting records · 473 recipient NPIs · example record 1206131384
Bevespi Aerosphere · 2024
Exact normalized brand match · 1 Part D row
15 suppressed by CMS
AstraZeneca Pharmaceuticals LP
Exact reporting entity; no affiliate inference
2025 FARXIGA
open payments reported associated product
CMS Open Payments — General Payments
106133 supporting records · 42906 recipient NPIs · example record 1206131362
Farxiga · 2024
Exact normalized brand match · 1 Part D row
46 suppressed by CMS
GlaxoSmithKline, LLC.
Exact reporting entity; no affiliate inference
2025 TRELEGY ELLIPTA
open payments reported associated product
CMS Open Payments — General Payments
131532 supporting records · 37148 recipient NPIs · example record 1190332369
Trelegy Ellipta · 2024
Exact normalized brand match · 1 Part D row
33 suppressed by CMS
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Ozempic
open payments reported associated product
CMS Open Payments — General Payments
261625 supporting records · 77793 recipient NPIs · example record 1188130076
Ozempic · 2024
Exact normalized brand match · 1 Part D row
45 suppressed by CMS
Novo Nordisk Inc
Exact reporting entity; no affiliate inference
2025 Rybelsus
open payments reported associated product
CMS Open Payments — General Payments
161257 supporting records · 55409 recipient NPIs · example record 1188130076
Rybelsus · 2024
Exact normalized brand match · 1 Part D row
11 suppressed by CMS
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 ELIQUIS
open payments reported associated product
CMS Open Payments — General Payments
87112 supporting records · 36032 recipient NPIs · example record 1228794063
Eliquis · 2024
Exact normalized brand match · 1 Part D row
99 25
PFIZER INC.
Exact reporting entity; no affiliate inference
2025 PAXLOVID
open payments reported associated product
CMS Open Payments — General Payments
24465 supporting records · 15715 recipient NPIs · example record 1228794432
Paxlovid · 2024
Exact normalized brand match · 1 Part D row
15 15

These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.

Public Medicare Part D data

Provider-and-drug rows loaded for 2024

BrandGenericClaimsBeneficiaries
Atorvastatin CalciumAtorvastatin Calcium648190
Levothyroxine SodiumLevothyroxine Sodium504134
Amlodipine BesylateAmlodipine Besylate385116
LisinoprilLisinopril28882
Losartan PotassiumLosartan Potassium27283
Metoprolol SuccinateMetoprolol Succinate25675
Tamsulosin HclTamsulosin Hcl22366
Rosuvastatin CalciumRosuvastatin Calcium21871
SimvastatinSimvastatin21753
Pantoprazole SodiumPantoprazole Sodium21255
OmeprazoleOmeprazole20463
Metformin HclMetformin Hcl19253
HydrochlorothiazideHydrochlorothiazide18355
AllopurinolAllopurinol16749
GabapentinGabapentin15146
Pravastatin SodiumPravastatin Sodium14643
Montelukast SodiumMontelukast Sodium13943
AlprazolamAlprazolam12533
Metformin Hcl ErMetformin Hcl12034
Escitalopram OxalateEscitalopram Oxalate11431
Trazodone HclTrazodone Hcl10727
Albuterol Sulfate HfaAlbuterol Sulfate10628
Lisinopril-HydrochlorothiazideLisinopril/Hydrochlorothiazide10432
Sertraline HclSertraline Hcl10329
EliquisApixaban9925
ClopidogrelClopidogrel Bisulfate9834
FurosemideFurosemide9633
Tramadol HclTramadol Hcl9520
MeloxicamMeloxicam9330
Duloxetine HclDuloxetine Hcl8920
Zolpidem TartrateZolpidem Tartrate8320
Cyclobenzaprine HclCyclobenzaprine Hcl8120
CarvedilolCarvedilol8024
ClonazepamClonazepam7917
LorazepamLorazepam7215
Metoprolol TartrateMetoprolol Tartrate7222
GlimepirideGlimepiride6921
Fluoxetine HclFluoxetine Hcl6719
Potassium ChloridePotassium Chloride6422
Hydrocodone-AcetaminophenHydrocodone/Acetaminophen6317
TrulicityDulaglutide61suppressed
EzetimibeEzetimibe6016
Losartan-HydrochlorothiazideLosartan/Hydrochlorothiazide6019
Fluticasone PropionateFluticasone Propionate5520
FamotidineFamotidine5418
JardianceEmpagliflozin5413
Bupropion XlBupropion Hcl5318
Alendronate SodiumAlendronate Sodium5116
Hydroxyzine HclHydroxyzine Hcl4911
SpironolactoneSpironolactone4913
FarxigaDapagliflozin Propanediol46suppressed
Warfarin SodiumWarfarin Sodium4612
Diclofenac SodiumDiclofenac Sodium4524
MethylprednisoloneMethylprednisolone4539
OzempicSemaglutide45suppressed
Oxycodone HclOxycodone Hcl42suppressed
MounjaroTirzepatide41suppressed
Dextroamphetamine-AmphetamineDextroamphetamine/Amphetamine40suppressed
AtenololAtenolol3913
SulindacSulindac39suppressed
Oxycodone-AcetaminophenOxycodone Hcl/Acetaminophen38suppressed
SynthroidLevothyroxine Sodium37suppressed
FinasterideFinasteride3611
Glipizide ErGlipizide36suppressed
Ondansetron OdtOndansetron3611
Nitrofurantoin Mono-MacroNitrofurantoin Monohyd/M-Cryst3519
MirtazapineMirtazapine34suppressed
ValsartanValsartan3411
CelecoxibCelecoxib33suppressed
Ropinirole HclRopinirole Hcl33suppressed
Trelegy ElliptaFluticasone/Umeclidin/Vilanter33suppressed
Fluticasone-SalmeterolFluticasone Propion/Salmeterol32suppressed
Hydroxyzine PamoateHydroxyzine Pamoate32suppressed
Pioglitazone HclPioglitazone Hcl32suppressed
PrednisonePrednisone3219
Clonidine HclClonidine Hcl31suppressed
Nifedipine ErNifedipine31suppressed
Venlafaxine Hcl ErVenlafaxine Hcl3111
Amlodipine Besylate-BenazeprilAmlodipine Besylate/Benazepril30suppressed
IrbesartanIrbesartan30suppressed
Liothyronine SodiumLiothyronine Sodium30suppressed
Triamterene-HydrochlorothiazidTriamterene/Hydrochlorothiazid30suppressed
Buspirone HclBuspirone Hcl29suppressed
IbuprofenIbuprofen29suppressed
Oxybutynin Chloride ErOxybutynin Chloride28suppressed
Benazepril HclBenazepril Hcl27suppressed
Citalopram HbrCitalopram Hydrobromide27suppressed
Doxazosin MesylateDoxazosin Mesylate27suppressed
DutasterideDutasteride27suppressed
MethocarbamolMethocarbamol27suppressed
PregabalinPregabalin27suppressed
CephalexinCephalexin2512
CholestyramineCholestyramine (With Sugar)25suppressed
Paroxetine HclParoxetine Hcl25suppressed
ValacyclovirValacyclovir Hcl2514
GlipizideGlipizide24suppressed
OlanzapineOlanzapine24suppressed
Testosterone CypionateTestosterone Cypionate24suppressed
Hydralazine HclHydralazine Hcl23suppressed
Oxybutynin ChlorideOxybutynin Chloride23suppressed
AmoxicillinAmoxicillin22suppressed
Basaglar Kwikpen U-100Insulin Glargine,hum.Rec.Anlog22suppressed
Doxycycline MonohydrateDoxycycline Monohydrate2218
EstradiolEstradiol22suppressed
Olmesartan MedoxomilOlmesartan Medoxomil22suppressed
RamiprilRamipril22suppressed
Triamcinolone AcetonideTriamcinolone Acetonide2214
Donepezil HclDonepezil Hcl21suppressed
Pramipexole DihydrochloridePramipexole Di-Hcl21suppressed
TopiramateTopiramate21suppressed
Valsartan-HydrochlorothiazideValsartan/Hydrochlorothiazide21suppressed
Verapamil ErVerapamil Hcl21suppressed
AzithromycinAzithromycin2019
FenofibrateFenofibrate Nanocrystallized20suppressed
JanuviaSitagliptin Phosphate20suppressed
Klor-Con M20Potassium Chloride20suppressed
LinzessLinaclotide20suppressed
Breo ElliptaFluticasone/Vilanterol19suppressed
Methylphenidate HclMethylphenidate Hcl19suppressed
Nebivolol HclNebivolol Hcl19suppressed
Quetiapine FumarateQuetiapine Fumarate19suppressed
Folic AcidFolic Acid18suppressed
Memantine HclMemantine Hcl18suppressed
Clobetasol PropionateClobetasol Propionate17suppressed
DigoxinDigoxin17suppressed
Ketorolac TromethamineKetorolac Tromethamine17suppressed
Sildenafil CitrateSildenafil Citrate17suppressed
Irbesartan-HydrochlorothiazideIrbesartan/Hydrochlorothiazide16suppressed
NitrofurantoinNitrofurantoin Macrocrystal16suppressed
NystatinNystatin16suppressed
Propranolol HclPropranolol Hcl16suppressed
BaclofenBaclofen15suppressed
Bevespi AerosphereGlycopyrrolate/Formoterol Fum15suppressed
DiazepamDiazepam15suppressed
Diltiazem 24hr Er (Cd)Diltiazem Hcl15suppressed
LamotrigineLamotrigine15suppressed
LovastatinLovastatin15suppressed
PaxlovidNirmatrelvir/Ritonavir1515
RizatriptanRizatriptan Benzoate15suppressed
ChlorthalidoneChlorthalidone14suppressed
EszopicloneEszopiclone14suppressed
LevetiracetamLevetiracetam14suppressed
Nalbuphine HclNalbuphine Hcl14suppressed
TelmisartanTelmisartan14suppressed
Atrovent HfaIpratropium Bromide13suppressed
Cetirizine HclCetirizine Hcl13suppressed
FenofibrateFenofibrate13suppressed
KetoconazoleKetoconazole13suppressed
TestosteroneTestosterone13suppressed
Zolpidem Tartrate ErZolpidem Tartrate13suppressed
Amoxicillin-Clavulanate PotassAmoxicillin/Potassium Clav1211
Betamethasone DipropionateBetamethasone Dipropionate12suppressed
Bupropion Hcl SrBupropion Hcl12suppressed
Clorazepate DipotassiumClorazepate Dipotassium12suppressed
EdluarZolpidem Tartrate12suppressed
JanumetSitagliptin Phos/Metformin Hcl12suppressed
MetronidazoleMetronidazole12suppressed
Sumatriptan SuccinateSumatriptan Succinate12suppressed
Terazosin HclTerazosin Hcl12suppressed
AripiprazoleAripiprazole11suppressed
Bisoprolol-HydrochlorothiazideBisoprolol/Hydrochlorothiazide11suppressed
Ciprofloxacin HclCiprofloxacin Hcl11suppressed
FebuxostatFebuxostat11suppressed
Nano 2nd Gen Pen NeedlePen Needle, Diabetic11suppressed
Omega-3 Acid Ethyl EstersOmega-3 Acid Ethyl Esters11suppressed
RybelsusSemaglutide11suppressed
SilodosinSilodosin11suppressed
TemazepamTemazepam11suppressed
Terbinafine HclTerbinafine Hcl11suppressed

Timeline

Payment and prescribing data by year

Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.

YearGeneral PaymentsMain payerExplicit productsCompany overlapsPart D coverage
2025 $733.47 · 39 records AstraZeneca Pharmaceuticals LP ABRYSVO, AIRSUPRA, Azstarys, BREZTRI, COMIRNATY, Cologuard Collection Kit, EVENITY, FARXIGA, FREESTYLE LIBRE 3, GEMTESA, Heplisav-B, Kerendia, Ozempic, PREVNAR 20, QULIPTA, REXULTI, Rybelsus, TRELEGY ELLIPTA, The Cologuard Plus Collection Kit, UBRELVY, Wegovy, XIFAXAN, ZORYVE 9
2024 Complete

Questions to ask

Questions you could discuss with your doctor

These are general questions generated from reviewed templates. They are not personalized medical advice.

Sources and limitations

How to read this page

Loaded source releases

DatasetYearPublicationSource
CMS Open Payments — General Payments 2025 2026-06-30 Original source
Medicare Part D Prescribers by Provider and Drug 2024 2026-05-06 Original source
NPPES Data Dissemination V2 current / reference data 2026-08-10 Original source

Methodology version: 2.1

Editorial template version: 2.4

Product contract version: 2.0

Schema version: 0.7.0

Page data build: 2026-08-12T23:34:59.370714+00:00

Publication policy: eligible for indexing after public-launch controls are enabled

Full methodology · Questions & answers · Report a possible error