Payment overview · 2025
General Payments
$1,820.37
69 reported records · 23 companies
Healthcare provider profile · identity verified
Ryan Manecke, M.D.
Allopathic & Osteopathic Physicians|Urology · JOLIET, IL · NPI 1942289129
Verified facts
What the public records show
CMS Open Payments records show Ryan Manecke, M.D. received $1,820.37 in general payments during 2025 across 69 reported records.
PROGENICS PHARMACEUTICALS, INC. accounted for 11.6% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 26 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Erleada, Gemtesa, Orgovyx.
Janssen Biotech, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ERLEADA as an associated drug or biological on 32382 records involving 10919 distinct recipient NPIs. Public Medicare Part D data also shows 39 claims for Erleada by this doctor in 2024.
Sumitomo Pharma America, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported GEMTESA as an associated drug or biological on 61692 records involving 22152 distinct recipient NPIs. Public Medicare Part D data also shows 26 claims for Gemtesa by this doctor in 2024.
Sumitomo Pharma America, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ORGOVYX as an associated drug or biological on 17129 records involving 6223 distinct recipient NPIs. Public Medicare Part D data also shows 20 claims for Orgovyx by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| PROGENICS PHARMACEUTICALS, INC. | Unresolved — no canonical attribution shown | $211.74 | 11.6% | 6 | 2025 |
| Janssen Biotech, Inc. | Unresolved — no canonical attribution shown | $206.93 | 11.4% | 9 | 2025 |
| Olympus America Inc. | Unresolved — no canonical attribution shown | $198.38 | 10.9% | 7 | 2025 |
| Procept Biorobotics Corporation | Unresolved — no canonical attribution shown | $166.36 | 9.1% | 2 | 2025 |
| Calyxo, Inc. | Unresolved — no canonical attribution shown | $155.66 | 8.6% | 1 | 2025 |
| COLOPLAST CORP | Unresolved — no canonical attribution shown | $135.97 | 7.5% | 7 | 2025 |
| Sumitomo Pharma America, Inc. | Unresolved — no canonical attribution shown | $135.45 | 7.4% | 8 | 2025 |
| Boston Scientific Corporation | Unresolved — no canonical attribution shown | $86.57 | 4.8% | 2 | 2025 |
| Endo USA, Inc. | Unresolved — no canonical attribution shown | $68.36 | 3.8% | 4 | 2025 |
| Novartis Pharmaceuticals Corporation | Unresolved — no canonical attribution shown | $64.83 | 3.6% | 3 | 2025 |
| Bayer Healthcare Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $58.77 | 3.2% | 3 | 2025 |
| Ferring Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $44.34 | 2.4% | 2 | 2025 |
| Verity Pharmaceuticals Inc. | Unresolved — no canonical attribution shown | $43.55 | 2.4% | 2 | 2025 |
| AstraZeneca Pharmaceuticals LP | Unresolved — no canonical attribution shown | $35.99 | 2.0% | 2 | 2025 |
| Merck Sharp & Dohme LLC | Unresolved — no canonical attribution shown | $33.70 | 1.9% | 2 | 2025 |
| UROGEN PHARMA, INC. | Unresolved — no canonical attribution shown | $33.47 | 1.8% | 2 | 2025 |
| 180 Medical, Inc. | Unresolved — no canonical attribution shown | $26.60 | 1.5% | 1 | 2025 |
| Telix Pharmaceuticals | Unresolved — no canonical attribution shown | $25.76 | 1.4% | 1 | 2025 |
| Laborie Medical Technologies Corp. | Unresolved — no canonical attribution shown | $22.84 | 1.2% | 1 | 2025 |
| ACCORD HEALTHCARE, INC. | Unresolved — no canonical attribution shown | $18.47 | 1.0% | 1 | 2025 |
| TOLMAR, INC. | Unresolved — no canonical attribution shown | $17.52 | 1.0% | 1 | 2025 |
| Antares Pharma, Inc. | Unresolved — no canonical attribution shown | $15.04 | 0.8% | 1 | 2025 |
| Avation Medical, Inc. | Unresolved — no canonical attribution shown | $14.07 | 0.8% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $1,820.37 | 69 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| PYLARIFY Normalized: pylarify |
Drug | PROGENICS PHARMACEUTICALS, INC. | $211.74 | 6 | 2025 |
Source payment records
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| ERLEADA Normalized: erleada |
Drug | Janssen Biotech, Inc. | $206.93 | 9 | 2025 |
Source payment records
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| iTIND System Normalized: itind system |
Device | Olympus America Inc. | $198.38 | 7 | 2025 |
Source payment records
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| AQUABEAM ROBOTIC SYSTEM Normalized: aquabeam robotic system |
Device | Procept Biorobotics Corporation | $166.36 | 2 | 2025 |
Source payment records
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| CVAC ASPIRATION SYSTEM Normalized: cvac aspiration system |
Device | Calyxo, Inc. | $155.66 | 1 | 2025 |
Source payment records
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| Coloplast TFL Drive Normalized: coloplast tfl drive |
Device | COLOPLAST CORP | $129.49 | 6 | 2025 |
Source payment records
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| SpaceOAR VUE System - 10mL Normalized: spaceoar vue system 10ml |
Device | Boston Scientific Corporation | $86.57 | 2 | 2025 |
Source payment records
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| GEMTESA Normalized: gemtesa |
Drug | Sumitomo Pharma America, Inc. | $72.17 | 4 | 2025 |
Source payment records
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| XIAFLEX Normalized: xiaflex |
Biological | Endo USA, Inc. | $68.36 | 4 | 2025 |
Source payment records
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| PLUVICTO Normalized: pluvicto |
Drug | Novartis Pharmaceuticals Corporation | $64.83 | 3 | 2025 |
Source payment records
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| ORGOVYX Normalized: orgovyx |
Drug | Sumitomo Pharma America, Inc. | $63.28 | 4 | 2025 |
Source payment records
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| Nubeqa Normalized: nubeqa |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $58.77 | 3 | 2025 |
Source payment records
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| Xofigo Normalized: xofigo |
Drug | Bayer Healthcare Pharmaceuticals Inc. | $58.77 | 3 | 2025 |
Source payment records
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| ADSTILADRIN Normalized: adstiladrin |
Biological | Ferring Pharmaceuticals Inc. | $44.34 | 2 | 2025 |
Source payment records
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| Trelstar Normalized: trelstar |
Drug | Verity Pharmaceuticals Inc. | $43.55 | 2 | 2025 |
Source payment records
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| LYNPARZA Normalized: lynparza |
Drug | AstraZeneca Pharmaceuticals LP | $35.99 | 2 | 2025 |
Source payment records
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| ILLUCCIX Normalized: illuccix |
Drug | Telix Pharmaceuticals | $25.76 | 1 | 2025 |
Source payment records
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| KEYTRUDA Normalized: keytruda |
Biological | Merck Sharp & Dohme LLC | $19.13 | 1 | 2025 |
Source payment records
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| ZUSDURI Normalized: zusduri |
Drug | UROGEN PHARMA, INC. | $19.01 | 1 | 2025 |
Source payment records
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| Camcevi Normalized: camcevi |
Drug | ACCORD HEALTHCARE, INC. | $18.47 | 1 | 2025 |
Source payment records
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| ELIGARD Normalized: eligard |
Drug | TOLMAR, INC. | $17.52 | 1 | 2025 |
Source payment records
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| XYOSTED Normalized: xyosted |
Drug | Antares Pharma, Inc. | $15.04 | 1 | 2025 |
Source payment records
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| BRIDION Normalized: bridion |
Drug | Merck Sharp & Dohme LLC | $14.57 | 1 | 2025 |
Source payment records
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| JELMYTO Normalized: jelmyto |
Drug | UROGEN PHARMA, INC. | $14.46 | 1 | 2025 |
Source payment records
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| Vivally System Normalized: vivally system |
Device | Avation Medical, Inc. | $14.07 | 1 | 2025 |
Source payment records
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| SpeediCath Normalized: speedicath |
Device | COLOPLAST CORP | $6.48 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| ERLEADA erleada |
2025 | Erleada | 2024 | 39 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| GEMTESA gemtesa |
2025 | Gemtesa | 2024 | 26 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| ORGOVYX orgovyx |
2025 | Orgovyx | 2024 | 20 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Janssen Biotech, Inc. Exact reporting entity; no affiliate inference |
2025 | ERLEADA open payments reported associated product |
CMS Open Payments — General Payments 32382 supporting records · 10919 recipient NPIs · example record 1174257499 |
Erleada · 2024 Exact normalized brand match · 1 Part D row |
39 | suppressed by CMS |
| Sumitomo Pharma America, Inc. Exact reporting entity; no affiliate inference |
2025 | GEMTESA open payments reported associated product |
CMS Open Payments — General Payments 61692 supporting records · 22152 recipient NPIs · example record 1176593503 |
Gemtesa · 2024 Exact normalized brand match · 1 Part D row |
26 | suppressed by CMS |
| Sumitomo Pharma America, Inc. Exact reporting entity; no affiliate inference |
2025 | ORGOVYX open payments reported associated product |
CMS Open Payments — General Payments 17129 supporting records · 6223 recipient NPIs · example record 1176593507 |
Orgovyx · 2024 Exact normalized brand match · 1 Part D row |
20 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Tamsulosin Hcl | Tamsulosin Hcl | 717 | 213 |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 242 | 89 |
| Finasteride | Finasteride | 213 | 65 |
| Myrbetriq | Mirabegron | 140 | 40 |
| Oxybutynin Chloride | Oxybutynin Chloride | 55 | 18 |
| Hydrocodone-Acetaminophen | Hydrocodone/Acetaminophen | 54 | 52 |
| Silodosin | Silodosin | 51 | 20 |
| Testosterone Cypionate | Testosterone Cypionate | 43 | suppressed |
| Ciprofloxacin Hcl | Ciprofloxacin Hcl | 39 | 33 |
| Erleada | Apalutamide | 39 | suppressed |
| Potassium Citrate Er | Potassium Citrate | 39 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 37 | 29 |
| Alfuzosin Hcl Er | Alfuzosin Hcl | 36 | 13 |
| Desmopressin Acetate | Desmopressin Acetate | 35 | suppressed |
| Amoxicillin-Clavulanate Potass | Amoxicillin/Potassium Clav | 27 | 20 |
| Gemtesa | Vibegron | 26 | suppressed |
| Testosterone | Testosterone | 26 | suppressed |
| Nitrofurantoin | Nitrofurantoin Macrocrystal | 22 | 18 |
| Orgovyx | Relugolix | 20 | suppressed |
| Cephalexin | Cephalexin | 16 | 14 |
| Dutasteride | Dutasteride | 15 | suppressed |
| Estradiol | Estradiol | 15 | suppressed |
| Xtandi | Enzalutamide | 15 | suppressed |
| Solifenacin Succinate | Solifenacin Succinate | 14 | suppressed |
| Allopurinol | Allopurinol | 12 | suppressed |
| Chlorthalidone | Chlorthalidone | 12 | suppressed |
| Tadalafil | Tadalafil | 12 | suppressed |
| Tolterodine Tartrate Er | Tolterodine Tartrate | 12 | suppressed |
| Amoxicillin | Amoxicillin | 11 | 11 |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $1,820.37 · 69 records | PROGENICS PHARMACEUTICALS, INC. | ADSTILADRIN, AQUABEAM ROBOTIC SYSTEM, BRIDION, CVAC ASPIRATION SYSTEM, Camcevi, Coloplast TFL Drive, ELIGARD, ERLEADA, GEMTESA, ILLUCCIX, JELMYTO, KEYTRUDA, LYNPARZA, Nubeqa, ORGOVYX, PLUVICTO, PYLARIFY, SpaceOAR VUE System - 10mL, SpeediCath, Trelstar, Vivally System, XIAFLEX, XYOSTED, Xofigo, ZUSDURI, iTIND System | 3 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Erleada play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Janssen Biotech, Inc.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error