Payment overview · 2025
General Payments
$1,055.45
59 reported records · 7 companies
Healthcare provider profile · identity verified
James C Charles, M.D.
Allopathic & Osteopathic Physicians|Internal Medicine · ROCK HILL, SC · NPI 1962405316
Verified facts
What the public records show
CMS Open Payments records show James C Charles, M.D. received $1,055.45 in general payments during 2025 across 59 reported records.
ViiV Healthcare Company accounted for 47.2% of that reported general-payment amount.
The Open Payments records used for this analysis explicitly named 14 associated products.
A separate comparison found the same explicitly named product in public Medicare Part D data: Biktarvy, Dovato, Pifeltro, Rukobia.
Gilead Sciences, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Biktarvy as an associated drug or biological on 8065 records involving 2759 distinct recipient NPIs. Public Medicare Part D data also shows 745 claims for Biktarvy by this doctor in 2024.
Gilead Sciences, Inc. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported Descovy as an associated drug or biological on 2032 records involving 589 distinct recipient NPIs. Public Medicare Part D data also shows 91 claims for Descovy by this doctor in 2024.
Merck Sharp & Dohme LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ISENTRESS as an associated drug or biological on 37 records involving 24 distinct recipient NPIs. Public Medicare Part D data also shows 24 claims for Isentress by this doctor in 2024.
Merck Sharp & Dohme LLC reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported PIFELTRO as an associated drug or biological on 7921 records involving 2912 distinct recipient NPIs. Public Medicare Part D data also shows 17 claims for Pifeltro by this doctor in 2024.
PFIZER INC. reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported ELIQUIS as an associated drug or biological on 87112 records involving 36032 distinct recipient NPIs. Public Medicare Part D data also shows 23 claims for Eliquis by this doctor in 2024.
ViiV Healthcare Company reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported DOVATO as an associated drug or biological on 18732 records involving 3540 distinct recipient NPIs. Public Medicare Part D data also shows 188 claims for Dovato by this doctor in 2024.
ViiV Healthcare Company reported payments to this doctor in 2025. Across the 2025 Open Payments General Payment records loaded for this analysis, that same reporting entity reported RUKOBIA as an associated drug or biological on 3367 records involving 1303 distinct recipient NPIs. Public Medicare Part D data also shows 23 claims for Rukobia by this doctor in 2024.
These records do not establish that a payment influenced prescribing or medical care.
Separate record types
Research & Ownership
Research Payments (direct recipient): not present in the loaded data
Associated Research Funding (for example, named PI): not present in the loaded data
Ownership / Investment: not present in the loaded data
These categories are never added into the General Payments headline. Associated research funding must not be described as money the doctor personally received unless the source record supports that conclusion.
Who paid this doctor?
Companies in 2025 General Payments
| Reported company | Canonical company | Amount | Share | Records | Year |
|---|---|---|---|---|---|
| ViiV Healthcare Company | Unresolved — no canonical attribution shown | $498.06 | 47.2% | 27 | 2025 |
| Gilead Sciences, Inc. | Unresolved — no canonical attribution shown | $290.53 | 27.5% | 17 | 2025 |
| Merck Sharp & Dohme LLC | Unresolved — no canonical attribution shown | $103.98 | 9.8% | 6 | 2025 |
| Novo Nordisk Inc | Unresolved — no canonical attribution shown | $86.23 | 8.2% | 5 | 2025 |
| SHIELD THERAPEUTICS INC | Unresolved — no canonical attribution shown | $43.58 | 4.1% | 2 | 2025 |
| Indivior Inc. | Unresolved — no canonical attribution shown | $18.54 | 1.8% | 1 | 2025 |
| PFIZER INC. | Unresolved — no canonical attribution shown | $14.53 | 1.4% | 1 | 2025 |
What were the payments for?
Payment categories
| Category | Amount | Records |
|---|---|---|
| Food and Beverage | $1,055.45 | 59 |
A meal, consulting fee, royalty, and travel payment describe different kinds of reported relationships and should not be interpreted as equivalent.
Analysis 1 · Payment-linked products
Products named in Open Payments records
| Reported product | Type | Reported company | Related amount* | Records | Year |
|---|---|---|---|---|---|
| DOVATO Normalized: dovato |
Drug | ViiV Healthcare Company | $211.12 | 11 | 2025 |
Source payment records
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| APRETUDE Normalized: apretude |
Drug | ViiV Healthcare Company | $115.90 | 5 | 2025 |
Source payment records
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| RUKOBIA Normalized: rukobia |
Drug | ViiV Healthcare Company | $112.00 | 7 | 2025 |
Source payment records
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| PIFELTRO Normalized: pifeltro |
Drug | Merck Sharp & Dohme LLC | $103.98 | 6 | 2025 |
Source payment records
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| Ozempic Normalized: ozempic |
Drug | Novo Nordisk Inc | $64.51 | 4 | 2025 |
Source payment records
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| Rybelsus Normalized: rybelsus |
Drug | Novo Nordisk Inc | $45.69 | 3 | 2025 |
Source payment records
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| ACCRUFER Normalized: accrufer |
Drug | SHIELD THERAPEUTICS INC | $43.58 | 2 | 2025 |
Source payment records
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| Biktarvy Normalized: biktarvy |
Drug | Gilead Sciences, Inc. | $37.81 | 2 | 2025 |
Source payment records
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| CABENUVA Normalized: cabenuva |
Drug | ViiV Healthcare Company | $30.72 | 3 | 2025 |
Source payment records
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| Wegovy Normalized: wegovy |
Drug | Novo Nordisk Inc | $21.72 | 1 | 2025 |
Source payment records
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| SUBLOCADE Normalized: sublocade |
Drug | Indivior Inc. | $18.54 | 1 | 2025 |
Source payment records
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| ABRYSVO Normalized: abrysvo |
Biological | PFIZER INC. | $14.53 | 1 | 2025 |
Source payment records
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| COMIRNATY Normalized: comirnaty |
Biological | PFIZER INC. | $14.53 | 1 | 2025 |
Source payment records
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| PREVNAR 20 Normalized: prevnar 20 |
Biological | PFIZER INC. | $14.53 | 1 | 2025 |
Source payment records
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* Product-associated amounts are non-additive because one payment record may name more than one product.
These products were named on specific Open Payments records. A named product does not show that the payment influenced treatment or prescribing.
Public prescribing for products named in payments
| Open Payments product | Payment year | Part D brand | Part D year | Claims | Match method | Source |
|---|---|---|---|---|---|---|
| Biktarvy biktarvy |
2025 | Biktarvy | 2024 | 745 | exact normalized | Medicare Part D |
| DOVATO dovato |
2025 | Dovato | 2024 | 188 | exact normalized | Medicare Part D |
| PIFELTRO pifeltro |
2025 | Pifeltro | 2024 | 17 Beneficiary count suppressed |
exact normalized | Medicare Part D |
| RUKOBIA rukobia |
2025 | Rukobia | 2024 | 23 Beneficiary count suppressed |
exact normalized | Medicare Part D |
The presence of the same drug in both datasets does not show that a payment caused or influenced a prescription.
Analysis 2 · Same-company prescribing overlap
Drugs reported in other payments from the same company that also appear in Medicare Part D
This analysis is independent from products named on this doctor’s individual payment records. A row appears only when the exact Open Payments reporting entity paid this doctor, that same reporting entity reported the drug or biological on at least 10 loaded General Payment records involving at least 2 distinct recipient NPIs, and this doctor has the same non-generic brand in public Part D data. This does not mean the company owns or manufactures the drug.
| Paying company | Payment year | Drug reported by same entity | Open Payments evidence | Part D | Claims | Beneficiaries |
|---|---|---|---|---|---|---|
| Gilead Sciences, Inc. Exact reporting entity; no affiliate inference |
2025 | Biktarvy open payments reported associated product |
CMS Open Payments — General Payments 8065 supporting records · 2759 recipient NPIs · example record 1234350766 |
Biktarvy · 2024 Exact normalized brand match · 1 Part D row |
745 | 75 |
| Gilead Sciences, Inc. Exact reporting entity; no affiliate inference |
2025 | Descovy open payments reported associated product |
CMS Open Payments — General Payments 2032 supporting records · 589 recipient NPIs · example record 1234351196 |
Descovy · 2024 Exact normalized brand match · 1 Part D row |
91 | 11 |
| Merck Sharp & Dohme LLC Exact reporting entity; no affiliate inference |
2025 | ISENTRESS open payments reported associated product |
CMS Open Payments — General Payments 37 supporting records · 24 recipient NPIs · example record 1238003286 |
Isentress · 2024 Exact normalized brand match · 1 Part D row |
24 | suppressed by CMS |
| Merck Sharp & Dohme LLC Exact reporting entity; no affiliate inference |
2025 | PIFELTRO open payments reported associated product |
CMS Open Payments — General Payments 7921 supporting records · 2912 recipient NPIs · example record 1237992198 |
Pifeltro · 2024 Exact normalized brand match · 1 Part D row |
17 | suppressed by CMS |
| PFIZER INC. Exact reporting entity; no affiliate inference |
2025 | ELIQUIS open payments reported associated product |
CMS Open Payments — General Payments 87112 supporting records · 36032 recipient NPIs · example record 1228794063 |
Eliquis · 2024 Exact normalized brand match · 1 Part D row |
23 | suppressed by CMS |
| ViiV Healthcare Company Exact reporting entity; no affiliate inference |
2025 | DOVATO open payments reported associated product |
CMS Open Payments — General Payments 18732 supporting records · 3540 recipient NPIs · example record 1189508902 |
Dovato · 2024 Exact normalized brand match · 1 Part D row |
188 | 22 |
| ViiV Healthcare Company Exact reporting entity; no affiliate inference |
2025 | RUKOBIA open payments reported associated product |
CMS Open Payments — General Payments 3367 supporting records · 1303 recipient NPIs · example record 1189508926 |
Rukobia · 2024 Exact normalized brand match · 1 Part D row |
23 | suppressed by CMS |
These facts do not show that a payment was for the drug, that the company owns or manufactures the drug, or that a payment caused or influenced prescribing.
Public Medicare Part D data
Provider-and-drug rows loaded for 2024
| Brand | Generic | Claims | Beneficiaries |
|---|---|---|---|
| Biktarvy | Bictegrav/Emtricit/Tenofov Ala | 745 | 75 |
| Amlodipine Besylate | Amlodipine Besylate | 248 | 36 |
| Pravastatin Sodium | Pravastatin Sodium | 194 | 29 |
| Gabapentin | Gabapentin | 191 | 26 |
| Dovato | Dolutegravir Sodium/Lamivudine | 188 | 22 |
| Triumeq | Abacavir/Dolutegravir/Lamivudi | 174 | 17 |
| Omeprazole | Omeprazole | 171 | 23 |
| Odefsey | Emtricitab/Rilpiviri/Tenof Ala | 165 | 18 |
| Symtuza | Darunavir/Cob/Emtri/Tenof Alaf | 160 | 18 |
| Hydrochlorothiazide | Hydrochlorothiazide | 153 | 23 |
| Juluca | Dolutegravir/Rilpivirine | 141 | 12 |
| Metformin Hcl | Metformin Hcl | 122 | 17 |
| Hydroxyzine Hcl | Hydroxyzine Hcl | 120 | 18 |
| Lisinopril | Lisinopril | 116 | 15 |
| Potassium Chloride | Potassium Chloride | 110 | 16 |
| Albuterol Sulfate Hfa | Albuterol Sulfate | 105 | 26 |
| Tivicay | Dolutegravir Sodium | 103 | 14 |
| Atorvastatin Calcium | Atorvastatin Calcium | 100 | 20 |
| Sertraline Hcl | Sertraline Hcl | 97 | 12 |
| Descovy | Emtricitabine/Tenofov Alafenam | 91 | 11 |
| Metoprolol Tartrate | Metoprolol Tartrate | 90 | 11 |
| Losartan Potassium | Losartan Potassium | 87 | 11 |
| Trazodone Hcl | Trazodone Hcl | 73 | suppressed |
| Furosemide | Furosemide | 71 | 13 |
| Tamsulosin Hcl | Tamsulosin Hcl | 67 | 12 |
| Levetiracetam | Levetiracetam | 65 | suppressed |
| Symbicort | Budesonide/Formoterol Fumarate | 64 | 12 |
| Meloxicam | Meloxicam | 62 | suppressed |
| Valacyclovir | Valacyclovir Hcl | 61 | suppressed |
| Hydralazine Hcl | Hydralazine Hcl | 57 | suppressed |
| Pregabalin | Pregabalin | 57 | suppressed |
| Amitriptyline Hcl | Amitriptyline Hcl | 54 | suppressed |
| Sulfamethoxazole-Trimethoprim | Sulfamethoxazole/Trimethoprim | 53 | suppressed |
| Rosuvastatin Calcium | Rosuvastatin Calcium | 51 | suppressed |
| Allopurinol | Allopurinol | 47 | suppressed |
| Diclofenac Sodium | Diclofenac Sodium | 46 | suppressed |
| Isentress Hd | Raltegravir Potassium | 46 | suppressed |
| Testosterone Cypionate | Testosterone Cypionate | 44 | suppressed |
| Prezcobix | Darunavir/Cobicistat | 43 | suppressed |
| Famotidine | Famotidine | 40 | suppressed |
| Fenofibrate | Fenofibrate | 38 | suppressed |
| Genvoya | Elviteg/Cob/Emtri/Tenof Alafen | 38 | suppressed |
| Pantoprazole Sodium | Pantoprazole Sodium | 37 | suppressed |
| Mirtazapine | Mirtazapine | 36 | suppressed |
| Montelukast Sodium | Montelukast Sodium | 35 | suppressed |
| Duloxetine Hcl | Duloxetine Hcl | 34 | suppressed |
| Ritonavir | Ritonavir | 34 | suppressed |
| Levothyroxine Sodium | Levothyroxine Sodium | 28 | suppressed |
| Oxybutynin Chloride Er | Oxybutynin Chloride | 27 | suppressed |
| Cyclobenzaprine Hcl | Cyclobenzaprine Hcl | 26 | suppressed |
| Fluticasone Propionate | Fluticasone Propionate | 26 | suppressed |
| Fluticasone-Salmeterol | Fluticasone Propion/Salmeterol | 25 | suppressed |
| Methimazole | Methimazole | 25 | suppressed |
| Tizanidine Hcl | Tizanidine Hcl | 25 | suppressed |
| Ezetimibe | Ezetimibe | 24 | suppressed |
| Isentress | Raltegravir Potassium | 24 | suppressed |
| Edurant | Rilpivirine Hcl | 23 | suppressed |
| Eliquis | Apixaban | 23 | suppressed |
| Rukobia | Fostemsavir Tromethamine | 23 | suppressed |
| Solifenacin Succinate | Solifenacin Succinate | 23 | suppressed |
| Acyclovir | Acyclovir | 20 | suppressed |
| Celecoxib | Celecoxib | 20 | suppressed |
| Efavirenz-Emtric-Tenofov Disop | Efavirenz/Emtricit/Tenofovr Df | 20 | suppressed |
| Tramadol Hcl | Tramadol Hcl | 20 | suppressed |
| Ibuprofen | Ibuprofen | 19 | suppressed |
| Prednisone | Prednisone | 19 | 14 |
| Triamcinolone Acetonide | Triamcinolone Acetonide | 19 | suppressed |
| Darunavir | Darunavir | 18 | suppressed |
| Ondansetron Hcl | Ondansetron Hcl | 18 | suppressed |
| Carvedilol | Carvedilol | 17 | suppressed |
| Linzess | Linaclotide | 17 | suppressed |
| Pifeltro | Doravirine | 17 | suppressed |
| Promethazine Hcl | Promethazine Hcl | 17 | suppressed |
| Propranolol Hcl | Propranolol Hcl | 17 | suppressed |
| Dapsone | Dapsone | 16 | suppressed |
| Glipizide | Glipizide | 16 | suppressed |
| Levocetirizine Dihydrochloride | Levocetirizine Dihydrochloride | 16 | suppressed |
| Losartan-Hydrochlorothiazide | Losartan/Hydrochlorothiazide | 16 | suppressed |
| Metoprolol Succinate | Metoprolol Succinate | 16 | suppressed |
| Paroxetine Hcl | Paroxetine Hcl | 16 | suppressed |
| Quetiapine Fumarate | Quetiapine Fumarate | 16 | suppressed |
| Tenofovir Disoproxil Fumarate | Tenofovir Disoproxil Fumarate | 16 | suppressed |
| Triamterene-Hydrochlorothiazid | Triamterene/Hydrochlorothiazid | 16 | suppressed |
| Dicyclomine Hcl | Dicyclomine Hcl | 15 | suppressed |
| Amlodipine Besylate-Benazepril | Amlodipine Besylate/Benazepril | 14 | suppressed |
| Atenolol | Atenolol | 14 | suppressed |
| Lisinopril-Hydrochlorothiazide | Lisinopril/Hydrochlorothiazide | 14 | suppressed |
| Roflumilast | Roflumilast | 14 | suppressed |
| Budesonide-Formoterol Fumarate | Budesonide/Formoterol Fumarate | 13 | suppressed |
| Efavirenz | Efavirenz | 13 | suppressed |
| Nevirapine Er | Nevirapine | 13 | suppressed |
| Novolog | Insulin Aspart | 13 | suppressed |
| Bupropion Xl | Bupropion Hcl | 12 | suppressed |
| Escitalopram Oxalate | Escitalopram Oxalate | 12 | suppressed |
| Etravirine | Etravirine | 12 | suppressed |
| Metoclopramide Hcl | Metoclopramide Hcl | 12 | suppressed |
| Oxybutynin Chloride | Oxybutynin Chloride | 12 | suppressed |
| Verapamil Sr | Verapamil Hcl | 12 | suppressed |
| Xarelto | Rivaroxaban | 12 | suppressed |
| Advair Diskus | Fluticasone Propion/Salmeterol | 11 | suppressed |
| Cyproheptadine Hcl | Cyproheptadine Hcl | 11 | suppressed |
| Fosamprenavir Calcium | Fosamprenavir Calcium | 11 | suppressed |
Timeline
Payment and prescribing data by year
Open Payments and Medicare Part D may refer to different years. They are shown separately rather than aligned as if they describe the same period.
| Year | General Payments | Main payer | Explicit products | Company overlaps | Part D coverage |
|---|---|---|---|---|---|
| 2025 | $1,055.45 · 59 records | ViiV Healthcare Company | ABRYSVO, ACCRUFER, APRETUDE, Biktarvy, CABENUVA, COMIRNATY, DOVATO, Ozempic, PIFELTRO, PREVNAR 20, RUKOBIA, Rybelsus, SUBLOCADE, Wegovy | 7 | — |
| 2024 | — | — | — | — | Complete |
Questions to ask
Questions you could discuss with your doctor
- What role, if any, does Biktarvy play in your treatment recommendations for me?
- How do you evaluate evidence when you have a financial relationship with Gilead Sciences, Inc.?
- Are there reasonable alternatives I should understand when we discuss treatment options?
- How should I interpret the industry-payment records shown here in the context of my care?
These are general questions generated from reviewed templates. They are not personalized medical advice.
Sources and limitations
How to read this page
- Payment and Medicare prescribing data can cover different years; every comparison shows both years explicitly.
- Part D does not represent a doctor’s entire practice; it excludes many patients and is subject to CMS public-release thresholds.
- Company–drug relationships must have an auditable source, a precise relationship type, and a valid evidence period. Unresolved mappings are not published.
- Generic drug claims are not attributed to a specific manufacturer without manufacturer-level evidence.
- When a source extract is incomplete, missing rows are never treated as proof of no payments or no prescriptions.
Loaded source releases
| Dataset | Year | Publication | Source |
|---|---|---|---|
| CMS Open Payments — General Payments | 2025 | 2026-06-30 | Original source |
| Medicare Part D Prescribers by Provider and Drug | 2024 | 2026-05-06 | Original source |
| NPPES Data Dissemination V2 | current / reference data | 2026-08-10 | Original source |
Full methodology · Questions & answers · Report a possible error